Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKR008W
Length:
625
Number of sequences:
5887
Description:
YKR008W RSC4 SGDID:S000001716, Chr XI from 452201-454078, Genome Release 64-1-1, Verified ORF, "Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q02206    625   RSC4_YEAST Chromatin structure-remodeling com...6250     1278     100     100GO:0016586; C:RSC complex; IDA:UniProtKB.
GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0006337; P:nucleosome disassembly; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:SGD.
2Q8BSQ9    1634   PB1_MOUSE Protein polybromo-1 OS=Mus musculus...544.2     34.3     30     52GO:0000776; C:kinetochore; IDA:MGI.::GO:0005634; C:nucleus; IC:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001974; P:blood vessel remodeling; TAS:DFLAT.::GO:0060948; P:cardiac vascular smooth muscle cell development; TAS:DFLAT.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0003349; P:epicardium-derived cardiac endothelial cell differentiation; TAS:DFLAT.::GO:0003007; P:heart morphogenesis; TAS:DFLAT.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001890; P:placenta development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:DFLAT.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.
3Q86U86    1689   PB1_HUMAN Protein polybromo-1 OS=Homo sapiens...870.004     44.3     30     49GO:0000228; C:nuclear chromosome; NAS:UniProtKB.
GO:0003682; F:chromatin binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006338; P:chromatin remodeling; TAS:UniProtKB.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q90941    1633   PB1_CHICK Protein polybromo-1 OS=Gallus gallu...870.003     44.3     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q09948    542   RSC4_SCHPO Chromatin structure-remodeling com...800.000004     53.5     31     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0016586; C:RSC complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6O74964    803   RSC1_SCHPO Chromatin structure-remodeling com...820.13     39.3     27     55GO:0000790; C:nuclear chromatin; ISS:PomBase.::GO:0016586; C:RSC complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7P25439    1638   BRM_DROME ATP-dependent helicase brm OS=Droso...680.021     42     41     57GO:0035060; C:brahma complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:FlyBase.::GO:0007409; P:axonogenesis; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0035172; P:hemocyte proliferation; TAS:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IGI:FlyBase.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IGI:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q8WZM0    464   GCN5_YARLI Histone acetyltransferase GCN5 OS=...737.6     33.1     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q03330    439   GCN5_YEAST Histone acetyltransferase GCN5 OS=...750.0000000004     65.9     41     63GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:SGD.::GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0003713; F:transcription coactivator activity; TAS:SGD.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q756G9    452   GCN5_ASHGO Histone acetyltransferase GCN5 OS=...573     34.7     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q9W0T1    2669   NU301_DROME Nucleosome-remodeling factor subu...880.000000002     65.1     39     58GO:0016589; C:NURF complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0030097; P:hemopoiesis; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0042766; P:nucleosome mobilization; IDA:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:FlyBase.::GO:0035073; P:pupariation; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IDA:FlyBase.
12A7Z019    1606   SMCA4_BOVIN Transcription activator BRG1 OS=B...970.0006     46.6     36     56GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13B2RWS6    2415   EP300_MOUSE Histone acetyltransferase p300 OS...1030.000000002     65.1     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0051216; P:cartilage development; NAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043627; P:response to estrogen stimulus; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14P51532    1647   SMCA4_HUMAN Transcription activator BRG1 OS=H...970.0006     47     36     56GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008094; F:DNA-dependent ATPase activity; IGI:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0070577; F:histone acetyl-lysine binding; IDA:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0030957; F:Tat protein binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IMP:BHF-UCL.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IMP:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; TAS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0003407; P:neural retina development; IEP:BHF-UCL.::GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.::GO:0043923; P:positive regulation by host of viral transcription; IMP:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q8K1P7    1613   SMCA4_RAT Transcription activator BRG1 OS=Rat...960.0005     47     36     56GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0016514; C:SWI/SNF complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:RGD.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006337; P:nucleosome disassembly; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q3TKT4    1613   SMCA4_MOUSE Transcription activator BRG1 OS=M...960.0005     47     36     56GO:0000792; C:heterochromatin; IDA:MGI.::GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0005719; C:nuclear euchromatin; IDA:MGI.::GO:0005726; C:perichromatin fibrils; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0016514; C:SWI/SNF complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0001832; P:blastocyst growth; IMP:MGI.::GO:0001835; P:blastocyst hatching; IMP:MGI.::GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0006338; P:chromatin remodeling; IMP:MGI.::GO:0060318; P:definitive erythrocyte differentiation; IMP:MGI.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:MGI.::GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.::GO:0048562; P:embryonic organ morphogenesis; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007403; P:glial cell fate determination; IMP:MGI.::GO:0060347; P:heart trabecula formation; IGI:MGI.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0043966; P:histone H3 acetylation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0006346; P:methylation-dependent chromatin silencing; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006334; P:nucleosome assembly; TAS:MGI.::GO:0043388; P:positive regulation of DNA binding; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0019827; P:stem cell maintenance; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001570; P:vasculogenesis; IMP:MGI.
17Q9UUK2    454   GCN5_SCHPO Histone acetyltransferase gcn5 OS=...671.7     35.4     30     58GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IGI:PomBase.::GO:0044154; P:histone H3-K14 acetylation; TAS:PomBase.::GO:0043971; P:histone H3-K18 acetylation; TAS:PomBase.::GO:0043972; P:histone H3-K23 acetylation; TAS:PomBase.::GO:0043970; P:histone H3-K9 acetylation; TAS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q09472    2414   EP300_HUMAN Histone acetyltransferase p300 OS...1030.000000002     64.3     36     58GO:0005813; C:centrosome; IDA:HPA.
GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043923; P:positive regulation by host of viral transcription; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q6FTW5    546   GCN5_CANGA Histone acetyltransferase GCN5 OS=...750.000000005     62.8     40     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q92793    2442   CBP_HUMAN CREB-binding protein OS=Homo sapien...930.00000001     62     35     60GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016604; C:nuclear body; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0043426; F:MRF binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; TAS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; TAS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.::GO:0042592; P:homeostatic process; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0008589; P:regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0001666; P:response to hypoxia; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
21O15164    1050   TIF1A_HUMAN Transcription intermediary factor...610.015     42.4     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0034056; F:estrogen response element binding; IDA:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
22Q6JHU9    2442   CBP_RAT CREB-binding protein OS=Rattus norveg...930.00000002     61.6     35     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:RGD.
GO:0033613; F:activating transcription factor binding; IPI:RGD.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0043426; F:MRF binding; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:RGD.::GO:0046332; F:SMAD binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IDA:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0033261; P:regulation of S phase; IMP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P45481    2441   CBP_MOUSE CREB-binding protein OS=Mus musculu...930.00000002     61.6     35     60GO:0000940; C:condensed chromosome outer kinetochore; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0043426; F:MRF binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030718; P:germ-line stem cell maintenance; IMP:MGI.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q9AR19    568   GCN5_ARATH Histone acetyltransferase GCN5 OS=...800.00000002     60.8     35     56GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.::GO:0010484; F:H3 histone acetyltransferase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009908; P:flower development; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0009416; P:response to light stimulus; IMP:TAIR.::GO:0010015; P:root morphogenesis; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q6CXW4    516   GCN5_KLULA Histone acetyltransferase GCN5 OS=...475.9     33.5     40     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q12830    3046   BPTF_HUMAN Nucleosome-remodeling factor subun...780.00000006     60.1     31     60GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0016589; C:NURF complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007420; P:brain development; IMP:HGNC.::GO:0006338; P:chromatin remodeling; IDA:HGNC.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:HGNC.::GO:0006351; P:transcription, DNA-dependent; IMP:HGNC.
27P51531    1590   SMCA2_HUMAN Probable global transcription act...680.037     40.8     38     59GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; TAS:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
28Q54BA2    806   Y3800_DICDI Ankyrin repeat, bromo and BTB dom...830.0000001     58.5     37     58
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004672; F:protein kinase activity; ISS:dictyBase.
29Q338B9    511   GCN5_ORYSJ Histone acetyltransferase GCN5 OS=...760.0000002     57.8     36     59
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q64127    1051   TIF1A_MOUSE Transcription intermediary factor...710.026     41.6     35     54GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005719; C:nuclear euchromatin; IDA:MGI.::GO:0005726; C:perichromatin fibrils; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0034056; F:estrogen response element binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:MGI.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0055074; P:calcium ion homeostasis; IMP:MGI.::GO:0071391; P:cellular response to estrogen stimulus; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0070562; P:regulation of vitamin D receptor signaling pathway; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q6DIC0    1577   SMCA2_MOUSE Probable global transcription act...970.002     45.4     34     57GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0016514; C:SWI/SNF complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; TAS:MGI.
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