rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | C8ZAU6 | 338 | SDHL_YEAS8 L-serine dehydratase OS=(Baker's y... | 284 | 3e-16 | 81.3 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 62 | B3LU13 | 338 | SDHL_YEAS1 L-serine dehydratase OS=Saccharomy... | 284 | 3e-16 | 81.3 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 63 | B5VKE8 | 338 | SDHL_YEAS6 L-serine dehydratase OS=Saccharomy... | 284 | 4e-16 | 80.9 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 64 | Q8VBT2 | 327 | SDHL_MOUSE L-serine dehydratase/L-threonine d... | 263 | 0.000000000000001 | 79.7 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 65 | Q8R238 | 329 | SDSL_MOUSE Serine dehydratase-like OS=Mus mus... | 147 | 0.000000000000002 | 79.3 | 31 | 51 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 66 | P0CF23 | 338 | SDH1_YEASX L-serine dehydratase OS=Saccharomy... | 284 | 0.000000000000002 | 79 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 67 | P74193 | 382 | THRC_SYNY3 Threonine synthase OS=Synechocysti... | 329 | 0.0000000000002 | 74.3 | 26 | 47 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 68 | Q86B06 | 350 | SDHL_DICDI L-serine dehydratase OS=Dictyostel... | 312 | 0.0000000000003 | 73.2 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; ISS:dictyBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006563; P:L-serine metabolic process; ISS:dictyBase. | 69 | Q96GA7 | 329 | SDSL_HUMAN Serine dehydratase-like OS=Homo sa... | 142 | 0.000000000001 | 71.2 | 32 | 52 | | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 70 | P20132 | 328 | SDHL_HUMAN L-serine dehydratase/L-threonine d... | 308 | 0.000000000003 | 70.1 | 26 | 46 | GO:0005739; C:mitochondrion; IDA:HPA. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; IDA:UniProtKB.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.::GO:0042866; P:pyruvate biosynthetic process; IDA:UniProtKB. | 71 | P35520 | 551 | CBS_HUMAN Cystathionine beta-synthase OS=Homo... | 293 | 0.00000000001 | 68.6 | 26 | 42 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0004122; F:cystathionine beta-synthase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0043418; P:homocysteine catabolic process; IDA:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0019448; P:L-cysteine catabolic process; IDA:UniProtKB.::GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; TAS:Reactome. | 72 | Q58H57 | 551 | CBS_MACFA Cystathionine beta-synthase OS=Maca... | 295 | 0.00000000002 | 68.2 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB. | 73 | Q0VCW4 | 327 | SDHL_BOVIN L-serine dehydratase/L-threonine d... | 266 | 0.00000000005 | 66.6 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; ISS:UniProtKB.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006565; P:L-serine catabolic process; ISS:UniProtKB.::GO:0042866; P:pyruvate biosynthetic process; ISS:UniProtKB. | 74 | Q91WT9 | 561 | CBS_MOUSE Cystathionine beta-synthase OS=Mus ... | 311 | 0.0000000002 | 65.5 | 26 | 41 | | | | | | | | | | | GO:0004122; F:cystathionine beta-synthase activity; IMP:MGI. | | | | | | | | | | GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IMP:MGI.::GO:0021587; P:cerebellum morphogenesis; IMP:MGI.::GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0001958; P:endochondral ossification; IMP:MGI.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.::GO:0050880; P:regulation of blood vessel size; IMP:MGI.::GO:0030823; P:regulation of cGMP metabolic process; IMP:MGI.::GO:0043506; P:regulation of JUN kinase activity; IMP:MGI.::GO:0051593; P:response to folic acid; IMP:MGI.::GO:0006801; P:superoxide metabolic process; IMP:MGI. | 75 | P66902 | 360 | THRC_MYCTU Threonine synthase OS=Mycobacteriu... | 274 | 0.0000000002 | 65.1 | 25 | 49 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IDA:MTBBASE.::GO:0004795; F:threonine synthase activity; IDA:MTBBASE. | | | | | | | | | | GO:0040007; P:growth; IMP:MTBBASE.::GO:0009088; P:threonine biosynthetic process; IMP:MTBBASE. | 76 | P66903 | 360 | THRC_MYCBO Threonine synthase OS=Mycobacteriu... | 274 | 0.0000000002 | 65.1 | 25 | 49 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 77 | A0R220 | 360 | THRC_MYCS2 Threonine synthase OS=Mycobacteriu... | 281 | 0.0000000002 | 64.7 | 25 | 47 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 78 | P09367 | 363 | SDHL_RAT L-serine dehydratase/L-threonine dea... | 298 | 0.0000000003 | 63.9 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003941; F:L-serine ammonia-lyase activity; TAS:RGD.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0046983; F:protein dimerization activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; TAS:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0033590; P:response to cobalamin; IEP:RGD. | 79 | P45837 | 360 | THRC_MYCLE Threonine synthase OS=Mycobacteriu... | 273 | 0.000000002 | 61.6 | 23 | 47 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 80 | Q58860 | 405 | THRC_METJA Threonine synthase OS=JCM 10045 / ... | 307 | 0.000000002 | 61.6 | 26 | 44 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 81 | Q9N0V7 | 551 | CBS_RABIT Cystathionine beta-synthase OS=Oryc... | 209 | 0.000000004 | 61.2 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB. | 82 | P32232 | 561 | CBS_RAT Cystathionine beta-synthase OS=Rattus... | 277 | 0.00000002 | 59.3 | 26 | 41 | GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004122; F:cystathionine beta-synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; TAS:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:RGD.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; IDA:RGD. | 83 | Q8TQD4 | 405 | THRC_METAC Threonine synthase OS=C2A). GN=thr... | 280 | 0.00000004 | 58.2 | 25 | 45 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC. | | | | | | | | | | GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW. | 84 | Q8CMT6 | 310 | CYSK_STAES Cysteine synthase OS=Staphylococcu... | 202 | 0.00000006 | 57 | 27 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 85 | Q5HRP1 | 310 | CYSK_STAEQ Cysteine synthase OS=Staphylococcu... | 202 | 0.00000006 | 57 | 27 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 86 | P16703 | 303 | CYSM_ECOLI Cysteine synthase B OS=Escherichia... | 281 | 0.00000006 | 57 | 23 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IDA:EcoCyc.::GO:0080146; F:L-cysteine desulfhydrase activity; IMP:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IDA:EcoCyc. | 87 | P63872 | 310 | CYSK_STAAW Cysteine synthase OS=Staphylococcu... | 202 | 0.0000003 | 55.1 | 26 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 88 | Q6GBX5 | 310 | CYSK_STAAS Cysteine synthase OS=Staphylococcu... | 202 | 0.0000003 | 55.1 | 26 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 89 | Q6GJF8 | 310 | CYSK_STAAR Cysteine synthase OS=Staphylococcu... | 202 | 0.0000003 | 55.1 | 26 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 90 | P63871 | 310 | CYSK_STAAN Cysteine synthase OS=Staphylococcu... | 202 | 0.0000003 | 55.1 | 26 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. | 91 | P63870 | 310 | CYSK_STAAM Cysteine synthase OS=Staphylococcu... | 202 | 0.0000003 | 55.1 | 26 | 43 | | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro. |