Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL218C
Length:
326
Number of sequences:
5887
Description:
YKL218C SRY1 SGDID:S000001701, Chr XI from 18339-17359, Genome Release 64-1-1, reverse complement, Verified ORF, "3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61C8ZAU6    338   SDHL_YEAS8 L-serine dehydratase OS=(Baker's y...2843e-16     81.3     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
62B3LU13    338   SDHL_YEAS1 L-serine dehydratase OS=Saccharomy...2843e-16     81.3     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
63B5VKE8    338   SDHL_YEAS6 L-serine dehydratase OS=Saccharomy...2844e-16     80.9     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
64Q8VBT2    327   SDHL_MOUSE L-serine dehydratase/L-threonine d...2630.000000000000001     79.7     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
65Q8R238    329   SDSL_MOUSE Serine dehydratase-like OS=Mus mus...1470.000000000000002     79.3     31     51GO:0005739; C:mitochondrion; IDA:MGI.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
66P0CF23    338   SDH1_YEASX L-serine dehydratase OS=Saccharomy...2840.000000000000002     79     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
67P74193    382   THRC_SYNY3 Threonine synthase OS=Synechocysti...3290.0000000000002     74.3     26     47
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
68Q86B06    350   SDHL_DICDI L-serine dehydratase OS=Dictyostel...3120.0000000000003     73.2     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; ISS:dictyBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006563; P:L-serine metabolic process; ISS:dictyBase.
69Q96GA7    329   SDSL_HUMAN Serine dehydratase-like OS=Homo sa...1420.000000000001     71.2     32     52
GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
70P20132    328   SDHL_HUMAN L-serine dehydratase/L-threonine d...3080.000000000003     70.1     26     46GO:0005739; C:mitochondrion; IDA:HPA.
GO:0003941; F:L-serine ammonia-lyase activity; IDA:UniProtKB.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.::GO:0042866; P:pyruvate biosynthetic process; IDA:UniProtKB.
71P35520    551   CBS_HUMAN Cystathionine beta-synthase OS=Homo...2930.00000000001     68.6     26     42GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0004122; F:cystathionine beta-synthase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0043418; P:homocysteine catabolic process; IDA:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0019448; P:L-cysteine catabolic process; IDA:UniProtKB.::GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; TAS:Reactome.
72Q58H57    551   CBS_MACFA Cystathionine beta-synthase OS=Maca...2950.00000000002     68.2     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.
73Q0VCW4    327   SDHL_BOVIN L-serine dehydratase/L-threonine d...2660.00000000005     66.6     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; ISS:UniProtKB.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006565; P:L-serine catabolic process; ISS:UniProtKB.::GO:0042866; P:pyruvate biosynthetic process; ISS:UniProtKB.
74Q91WT9    561   CBS_MOUSE Cystathionine beta-synthase OS=Mus ...3110.0000000002     65.5     26     41
GO:0004122; F:cystathionine beta-synthase activity; IMP:MGI.
GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IMP:MGI.::GO:0021587; P:cerebellum morphogenesis; IMP:MGI.::GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0001958; P:endochondral ossification; IMP:MGI.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.::GO:0050880; P:regulation of blood vessel size; IMP:MGI.::GO:0030823; P:regulation of cGMP metabolic process; IMP:MGI.::GO:0043506; P:regulation of JUN kinase activity; IMP:MGI.::GO:0051593; P:response to folic acid; IMP:MGI.::GO:0006801; P:superoxide metabolic process; IMP:MGI.
75P66902    360   THRC_MYCTU Threonine synthase OS=Mycobacteriu...2740.0000000002     65.1     25     49GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IDA:MTBBASE.::GO:0004795; F:threonine synthase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0009088; P:threonine biosynthetic process; IMP:MTBBASE.
76P66903    360   THRC_MYCBO Threonine synthase OS=Mycobacteriu...2740.0000000002     65.1     25     49
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
77A0R220    360   THRC_MYCS2 Threonine synthase OS=Mycobacteriu...2810.0000000002     64.7     25     47
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
78P09367    363   SDHL_RAT L-serine dehydratase/L-threonine dea...2980.0000000003     63.9     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003941; F:L-serine ammonia-lyase activity; TAS:RGD.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0046983; F:protein dimerization activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; TAS:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0033590; P:response to cobalamin; IEP:RGD.
79P45837    360   THRC_MYCLE Threonine synthase OS=Mycobacteriu...2730.000000002     61.6     23     47
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
80Q58860    405   THRC_METJA Threonine synthase OS=JCM 10045 / ...3070.000000002     61.6     26     44
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
81Q9N0V7    551   CBS_RABIT Cystathionine beta-synthase OS=Oryc...2090.000000004     61.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.
82P32232    561   CBS_RAT Cystathionine beta-synthase OS=Rattus...2770.00000002     59.3     26     41GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004122; F:cystathionine beta-synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; TAS:RGD.
GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:RGD.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; IDA:RGD.
83Q8TQD4    405   THRC_METAC Threonine synthase OS=C2A). GN=thr...2800.00000004     58.2     25     45
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
84Q8CMT6    310   CYSK_STAES Cysteine synthase OS=Staphylococcu...2020.00000006     57     27     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
85Q5HRP1    310   CYSK_STAEQ Cysteine synthase OS=Staphylococcu...2020.00000006     57     27     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
86P16703    303   CYSM_ECOLI Cysteine synthase B OS=Escherichia...2810.00000006     57     23     43
GO:0004124; F:cysteine synthase activity; IDA:EcoCyc.::GO:0080146; F:L-cysteine desulfhydrase activity; IMP:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IDA:EcoCyc.
87P63872    310   CYSK_STAAW Cysteine synthase OS=Staphylococcu...2020.0000003     55.1     26     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
88Q6GBX5    310   CYSK_STAAS Cysteine synthase OS=Staphylococcu...2020.0000003     55.1     26     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
89Q6GJF8    310   CYSK_STAAR Cysteine synthase OS=Staphylococcu...2020.0000003     55.1     26     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
90P63871    310   CYSK_STAAN Cysteine synthase OS=Staphylococcu...2020.0000003     55.1     26     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
91P63870    310   CYSK_STAAM Cysteine synthase OS=Staphylococcu...2020.0000003     55.1     26     43
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
records
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