Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL216W
Length:
314
Number of sequences:
5887
Description:
YKL216W URA1 SGDID:S000001699, Chr XI from 25215-26159, Genome Release 64-1-1, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q7W4W6    349   PYRD_BORPA Dihydroorotate dehydrogenase (quin...2900.0000000003     63.9     24     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
212Q8CHR6    1025   DPYD_MOUSE Dihydropyrimidine dehydrogenase [N...3160.0000000003     64.7     25     42GO:0005829; C:cytosol; IDA:MGI.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
213O89000    1025   DPYD_RAT Dihydropyrimidine dehydrogenase [NAD...3170.0000000003     64.7     25     42GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0002058; F:uracil binding; IDA:RGD.
GO:0007623; P:circadian rhythm; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IDA:RGD.::GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
214Q113R9    378   PYRD_TRIEI Dihydroorotate dehydrogenase (quin...2950.0000000003     63.9     23     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
215A5UC11    339   PYRD_HAEIE Dihydroorotate dehydrogenase (quin...2680.0000000004     63.5     24     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
216Q9FB59    359   PYRD_CORST Dihydroorotate dehydrogenase (quin...2750.0000000004     63.5     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
217Q18164    1059   DPYD_CAEEL Dihydropyrimidine dehydrogenase [N...3160.0000000004     64.3     22     45GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
218Q31RJ7    378   PYRD_SYNE7 Dihydroorotate dehydrogenase (quin...2770.0000000005     63.5     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
219Q7WGE4    349   PYRD_BORBR Dihydroorotate dehydrogenase (quin...2900.0000000005     63.5     24     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
220A0PQW5    360   PYRD_MYCUA Dihydroorotate dehydrogenase (quin...2890.0000000005     63.5     24     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
221C5BKZ2    339   PYRD_TERTT Dihydroorotate dehydrogenase (quin...2540.0000000005     63.5     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
222Q5N2Q8    378   PYRD_SYNP6 Dihydroorotate dehydrogenase (quin...2770.0000000005     63.5     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
223A6V325    342   PYRD_PSEA7 Dihydroorotate dehydrogenase (quin...2890.0000000005     63.2     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
224Q7VTR9    349   PYRD_BORPE Dihydroorotate dehydrogenase (quin...2900.0000000005     63.2     24     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
225Q8FTC6    377   PYRD_COREF Dihydroorotate dehydrogenase (quin...2830.0000000007     63.2     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
226Q8K9I5    336   PYRD_BUCAP Dihydroorotate dehydrogenase (quin...2850.0000000007     62.8     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
227B8HW33    375   PYRD_CYAP4 Dihydroorotate dehydrogenase (quin...3240.0000000007     63.2     21     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
228Q3KFC7    339   PYRD_PSEPF Dihydroorotate dehydrogenase (quin...2910.000000001     62.4     25     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
229Q87A77    351   PYRD_XYLFT Dihydroorotate dehydrogenase (quin...3190.000000001     62.4     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
230B2I9T5    351   PYRD_XYLF2 Dihydroorotate dehydrogenase (quin...3190.000000001     62.4     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
231Q21JW9    339   PYRD_SACD2 Dihydroorotate dehydrogenase (quin...2560.000000001     62.4     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
232B0U5I1    351   PYRD_XYLFM Dihydroorotate dehydrogenase (quin...3190.000000001     62.4     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
233Q1J132    361   PYRD_DEIGD Dihydroorotate dehydrogenase (quin...3320.000000001     62.4     23     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
234A4SME2    336   PYRD_AERS4 Dihydroorotate dehydrogenase (quin...2990.000000001     62     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
235A9BWU2    348   PYRD_DELAS Dihydroorotate dehydrogenase (quin...2650.000000001     62.4     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
236Q129L9    350   PYRD_POLSJ Dihydroorotate dehydrogenase (quin...2890.000000001     62.4     25     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
237A7IBC2    357   PYRD_XANP2 Dihydroorotate dehydrogenase (quin...3220.000000001     62     24     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
238A9AJX4    345   PYRD_BURM1 Dihydroorotate dehydrogenase (quin...3030.000000002     62     25     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
239Q2SVL9    345   PYRD_BURTA Dihydroorotate dehydrogenase (quin...3030.000000002     62     25     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
240B2HFZ1    360   PYRD_MYCMM Dihydroorotate dehydrogenase (quin...2890.000000002     62     24     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
241B3PIL8    342   PYRD_CELJU Dihydroorotate dehydrogenase (quin...2560.000000002     61.6     27     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
records
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