rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q5R895 | 1025 | DPYD_PONAB Dihydropyrimidine dehydrogenase [N... | 237 | 0.00000000003 | 67.8 | 24 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 182 | Q0A8M5 | 340 | PYRD_ALHEH Dihydroorotate dehydrogenase (quin... | 313 | 0.00000000003 | 67 | 24 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 183 | Q02127 | 395 | PYRD_HUMAN Dihydroorotate dehydrogenase (quin... | 324 | 0.00000000003 | 67.4 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; NAS:UniProtKB. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; NAS:UniProtKB.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 184 | Q7U3U2 | 396 | PYRD_SYNPX Dihydroorotate dehydrogenase (quin... | 272 | 0.00000000004 | 67 | 26 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 185 | Q8YPC6 | 376 | PYRD_NOSS1 Dihydroorotate dehydrogenase (quin... | 274 | 0.00000000005 | 66.2 | 26 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 186 | B1J5B5 | 341 | PYRD_PSEPW Dihydroorotate dehydrogenase (quin... | 287 | 0.00000000005 | 66.2 | 26 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 187 | Q5E9W3 | 395 | PYRD_BOVIN Dihydroorotate dehydrogenase (quin... | 323 | 0.00000000006 | 66.2 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 188 | P32748 | 405 | PYRD_DROME Dihydroorotate dehydrogenase (quin... | 332 | 0.00000000006 | 66.2 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IDA:FlyBase. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 189 | B1WUM4 | 379 | PYRD_CYAA5 Dihydroorotate dehydrogenase (quin... | 287 | 0.00000000007 | 66.2 | 24 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 190 | Q3MDU0 | 376 | PYRD_ANAVT Dihydroorotate dehydrogenase (quin... | 274 | 0.00000000008 | 65.9 | 26 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 191 | A1TPZ2 | 359 | PYRD_ACIAC Dihydroorotate dehydrogenase (quin... | 291 | 0.00000000009 | 65.5 | 25 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 192 | B0KG90 | 341 | PYRD_PSEPG Dihydroorotate dehydrogenase (quin... | 287 | 0.0000000001 | 65.5 | 25 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 193 | A8XKG6 | 1053 | DPYD_CAEBR Probable dihydropyrimidine dehydro... | 316 | 0.0000000001 | 66.2 | 23 | 44 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 194 | Q6SZS5 | 439 | PYRD_CANGA Dihydroorotate dehydrogenase (quin... | 341 | 0.0000000001 | 65.5 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 195 | C1ASU1 | 356 | PYRD_RHOOB Dihydroorotate dehydrogenase (quin... | 274 | 0.0000000001 | 65.1 | 26 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 196 | A0QZY9 | 354 | PYRD_MYCS2 Dihydroorotate dehydrogenase (quin... | 271 | 0.0000000001 | 65.1 | 25 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 197 | Q4QKB5 | 339 | PYRD_HAEI8 Dihydroorotate dehydrogenase (quin... | 268 | 0.0000000001 | 65.1 | 25 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 198 | A4XWQ0 | 340 | PYRD_PSEMY Dihydroorotate dehydrogenase (quin... | 317 | 0.0000000001 | 65.1 | 25 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 199 | B1XV77 | 344 | PYRD_POLNS Dihydroorotate dehydrogenase (quin... | 302 | 0.0000000002 | 64.7 | 25 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 200 | Q1ICL4 | 340 | PYRD_PSEE4 Dihydroorotate dehydrogenase (quin... | 288 | 0.0000000002 | 64.7 | 26 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 201 | Q480K7 | 336 | PYRD_COLP3 Dihydroorotate dehydrogenase (quin... | 274 | 0.0000000002 | 64.3 | 26 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 202 | Q7NX17 | 344 | PYRD_CHRVO Dihydroorotate dehydrogenase (quin... | 308 | 0.0000000002 | 64.3 | 24 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 203 | A6T106 | 345 | PYRD_JANMA Dihydroorotate dehydrogenase (quin... | 301 | 0.0000000003 | 64.3 | 25 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 204 | Q2Y5H8 | 348 | PYRD_NITMU Dihydroorotate dehydrogenase (quin... | 302 | 0.0000000003 | 64.3 | 25 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 205 | P45477 | 339 | PYRD_HAEIN Dihydroorotate dehydrogenase (quin... | 268 | 0.0000000003 | 64.3 | 24 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 206 | Q65TR8 | 340 | PYRD_MANSM Dihydroorotate dehydrogenase (quin... | 281 | 0.0000000003 | 64.3 | 25 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 207 | Q2KW44 | 349 | PYRD_BORA1 Dihydroorotate dehydrogenase (quin... | 311 | 0.0000000003 | 64.3 | 24 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 208 | Q28943 | 1025 | DPYD_PIG Dihydropyrimidine dehydrogenase [NAD... | 236 | 0.0000000003 | 64.7 | 25 | 44 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB. | 209 | C1DDY1 | 347 | PYRD_AZOVD Dihydroorotate dehydrogenase (quin... | 318 | 0.0000000003 | 63.9 | 25 | 41 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 210 | A5UEP8 | 339 | PYRD_HAEIG Dihydroorotate dehydrogenase (quin... | 268 | 0.0000000003 | 63.9 | 24 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 211 | Q7W4W6 | 349 | PYRD_BORPA Dihydroorotate dehydrogenase (quin... | 290 | 0.0000000003 | 63.9 | 24 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. |