Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL216W
Length:
314
Number of sequences:
5887
Description:
YKL216W URA1 SGDID:S000001699, Chr XI from 25215-26159, Genome Release 64-1-1, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q5R895    1025   DPYD_PONAB Dihydropyrimidine dehydrogenase [N...2370.00000000003     67.8     24     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
182Q0A8M5    340   PYRD_ALHEH Dihydroorotate dehydrogenase (quin...3130.00000000003     67     24     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
183Q02127    395   PYRD_HUMAN Dihydroorotate dehydrogenase (quin...3240.00000000003     67.4     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; NAS:UniProtKB.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; NAS:UniProtKB.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
184Q7U3U2    396   PYRD_SYNPX Dihydroorotate dehydrogenase (quin...2720.00000000004     67     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
185Q8YPC6    376   PYRD_NOSS1 Dihydroorotate dehydrogenase (quin...2740.00000000005     66.2     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
186B1J5B5    341   PYRD_PSEPW Dihydroorotate dehydrogenase (quin...2870.00000000005     66.2     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
187Q5E9W3    395   PYRD_BOVIN Dihydroorotate dehydrogenase (quin...3230.00000000006     66.2     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
188P32748    405   PYRD_DROME Dihydroorotate dehydrogenase (quin...3320.00000000006     66.2     26     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IDA:FlyBase.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
189B1WUM4    379   PYRD_CYAA5 Dihydroorotate dehydrogenase (quin...2870.00000000007     66.2     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
190Q3MDU0    376   PYRD_ANAVT Dihydroorotate dehydrogenase (quin...2740.00000000008     65.9     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
191A1TPZ2    359   PYRD_ACIAC Dihydroorotate dehydrogenase (quin...2910.00000000009     65.5     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
192B0KG90    341   PYRD_PSEPG Dihydroorotate dehydrogenase (quin...2870.0000000001     65.5     25     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
193A8XKG6    1053   DPYD_CAEBR Probable dihydropyrimidine dehydro...3160.0000000001     66.2     23     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
194Q6SZS5    439   PYRD_CANGA Dihydroorotate dehydrogenase (quin...3410.0000000001     65.5     23     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
195C1ASU1    356   PYRD_RHOOB Dihydroorotate dehydrogenase (quin...2740.0000000001     65.1     26     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
196A0QZY9    354   PYRD_MYCS2 Dihydroorotate dehydrogenase (quin...2710.0000000001     65.1     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
197Q4QKB5    339   PYRD_HAEI8 Dihydroorotate dehydrogenase (quin...2680.0000000001     65.1     25     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
198A4XWQ0    340   PYRD_PSEMY Dihydroorotate dehydrogenase (quin...3170.0000000001     65.1     25     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
199B1XV77    344   PYRD_POLNS Dihydroorotate dehydrogenase (quin...3020.0000000002     64.7     25     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
200Q1ICL4    340   PYRD_PSEE4 Dihydroorotate dehydrogenase (quin...2880.0000000002     64.7     26     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
201Q480K7    336   PYRD_COLP3 Dihydroorotate dehydrogenase (quin...2740.0000000002     64.3     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
202Q7NX17    344   PYRD_CHRVO Dihydroorotate dehydrogenase (quin...3080.0000000002     64.3     24     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
203A6T106    345   PYRD_JANMA Dihydroorotate dehydrogenase (quin...3010.0000000003     64.3     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
204Q2Y5H8    348   PYRD_NITMU Dihydroorotate dehydrogenase (quin...3020.0000000003     64.3     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
205P45477    339   PYRD_HAEIN Dihydroorotate dehydrogenase (quin...2680.0000000003     64.3     24     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
206Q65TR8    340   PYRD_MANSM Dihydroorotate dehydrogenase (quin...2810.0000000003     64.3     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
207Q2KW44    349   PYRD_BORA1 Dihydroorotate dehydrogenase (quin...3110.0000000003     64.3     24     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
208Q28943    1025   DPYD_PIG Dihydropyrimidine dehydrogenase [NAD...2360.0000000003     64.7     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
209C1DDY1    347   PYRD_AZOVD Dihydroorotate dehydrogenase (quin...3180.0000000003     63.9     25     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
210A5UEP8    339   PYRD_HAEIG Dihydroorotate dehydrogenase (quin...2680.0000000003     63.9     24     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
211Q7W4W6    349   PYRD_BORPA Dihydroorotate dehydrogenase (quin...2900.0000000003     63.9     24     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
records
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