Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL216W
Length:
314
Number of sequences:
5887
Description:
YKL216W URA1 SGDID:S000001699, Chr XI from 25215-26159, Genome Release 64-1-1, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151A5IK84    270   PYRDB_THEP1 Dihydroorotate dehydrogenase B (N...2660.00000000000009     73.2     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
152Q9WYG8    270   PYRDB_THEMA Dihydroorotate dehydrogenase B (N...2660.00000000000009     73.2     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
153B7KIU7    377   PYRD_CYAP7 Dihydroorotate dehydrogenase (quin...2880.0000000000003     73.2     24     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
154A9I8M0    349   PYRD_BORPD Dihydroorotate dehydrogenase (quin...3000.0000000000003     72.8     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
155Q9UX04    290   PYRDB_SULSO Dihydroorotate dehydrogenase B (N...2950.0000000000003     72     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
156A8HZX8    356   PYRD_AZOC5 Dihydroorotate dehydrogenase (quin...3240.0000000000004     72.8     23     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
157O35435    395   PYRD_MOUSE Dihydroorotate dehydrogenase (quin...3230.0000000000005     72.4     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
158B1MPD4    353   PYRD_MYCA9 Dihydroorotate dehydrogenase (quin...2710.0000000000006     72     26     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
159P32747    443   PYRD_SCHPO Dihydroorotate dehydrogenase (quin...3040.0000000000006     72.4     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IDA:PomBase.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:PomBase.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
160Q2GBY1    349   PYRD_NOVAD Dihydroorotate dehydrogenase (quin...3210.000000000001     71.2     24     40GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
161A1W7S6    351   PYRD_ACISJ Dihydroorotate dehydrogenase (quin...2870.000000000001     71.2     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
162B0CA74    374   PYRD_ACAM1 Dihydroorotate dehydrogenase (quin...2830.000000000001     71.2     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
163Q75CE1    444   PYRD_ASHGO Dihydroorotate dehydrogenase (quin...3460.000000000002     71.2     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
164A1TZG0    340   PYRD_MARAV Dihydroorotate dehydrogenase (quin...3050.000000000002     70.5     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
165Q5YVM8    369   PYRD_NOCFA Dihydroorotate dehydrogenase (quin...2770.000000000002     70.5     27     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
166P57858    339   PYRD_PASMU Dihydroorotate dehydrogenase (quin...2980.000000000002     70.1     25     45GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
167A6VW35    346   PYRD_MARMS Dihydroorotate dehydrogenase (quin...2700.000000000003     70.1     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
168Q15UB7    335   PYRD_PSEA6 Dihydroorotate dehydrogenase (quin...3080.000000000005     69.3     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
169Q88L40    340   PYRD_PSEPK Dihydroorotate dehydrogenase (quin...2870.000000000006     68.9     26     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
170B9MIU2    351   PYRD_ACIET Dihydroorotate dehydrogenase (quin...2890.000000000009     68.6     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
171Q1B765    356   PYRD_MYCSS Dihydroorotate dehydrogenase (quin...2720.00000000001     68.6     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
172A1UHW0    356   PYRD_MYCSK Dihydroorotate dehydrogenase (quin...2720.00000000001     68.6     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
173A3Q1C6    356   PYRD_MYCSJ Dihydroorotate dehydrogenase (quin...2720.00000000001     68.6     27     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
174Q28007    1025   DPYD_BOVIN Dihydropyrimidine dehydrogenase [N...2370.00000000001     68.9     25     43GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
175Q5R6X6    395   PYRD_PONAB Dihydroorotate dehydrogenase (quin...3230.00000000001     68.2     23     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
176Q55FT1    1009   DPYD_DICDI Dihydropyrimidine dehydrogenase [N...2370.00000000002     68.6     25     44GO:0005829; C:cytosol; ISS:dictyBase.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
177Q12882    1025   DPYD_HUMAN Dihydropyrimidine dehydrogenase [N...2370.00000000002     68.6     24     44GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050661; F:NADP binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0006145; P:purine base catabolic process; IMP:UniProtKB.::GO:0006214; P:thymidine catabolic process; IDA:UniProtKB.::GO:0006210; P:thymine catabolic process; IDA:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; IDA:UniProtKB.
178P74782    381   PYRD_SYNY3 Dihydroorotate dehydrogenase (quin...2870.00000000002     67.8     24     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
179A4G7T7    347   PYRD_HERAR Dihydroorotate dehydrogenase (quin...3020.00000000002     67.4     25     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
180Q2JJF3    381   PYRD_SYNJB Dihydroorotate dehydrogenase (quin...2700.00000000003     67.4     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
181Q5R895    1025   DPYD_PONAB Dihydropyrimidine dehydrogenase [N...2370.00000000003     67.8     24     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO:0006214; P:thymidine catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.::GO:0006212; P:uracil catabolic process; ISS:UniProtKB.
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