Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL216W
Length:
314
Number of sequences:
5887
Description:
YKL216W URA1 SGDID:S000001699, Chr XI from 25215-26159, Genome Release 64-1-1, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121B9IVW1    309   PYRDB_BACCQ Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
122B7HLL8    309   PYRDB_BACC7 Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
123C1EPP8    309   PYRDB_BACC3 Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
124Q732I5    309   PYRDB_BACC1 Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
125B7JJX1    309   PYRDB_BACC0 Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
126Q81WF4    309   PYRDB_BACAN Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
127C3L742    309   PYRDB_BACAC Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
128C3P654    309   PYRDB_BACAA Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
129Q38X22    307   PYRDB_LACSS Dihydroorotate dehydrogenase B (N...2812e-19     89.7     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
130A0RHQ6    309   PYRDB_BACAH Dihydroorotate dehydrogenase B (N...3052e-19     89.7     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
131A9VTC4    309   PYRDB_BACWK Dihydroorotate dehydrogenase B (N...3053e-19     89.4     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
132Q6A912    307   PYRDB_PROAC Dihydroorotate dehydrogenase B (N...3031e-18     87.8     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
133Q74CB9    305   PYRDB_GEOSL Dihydroorotate dehydrogenase B (N...3223e-18     86.7     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
134O08358    291   PYRDB_SULAC Dihydroorotate dehydrogenase B (N...3001e-17     84.3     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
135Q9YFI6    306   PYRDA_AERPE Putative dihydroorotate dehydroge...3083e-17     84     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0052888; F:dihydroorotate oxidase (fumarate) activity; IEA:EC.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
136Q7NC99    353   PYRD_GLOVI Dihydroorotate dehydrogenase (quin...3213e-16     81.6     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
137Q8ZNL7    411   PREA_SALTY NAD-dependent dihydropyrimidine de...2400.000000000000001     80.5     28     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004159; F:dihydrouracil dehydrogenase (NAD+) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003954; F:NADH dehydrogenase activity; ISS:UniProtKB.
GO:0006208; P:pyrimidine base catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
138A4SWU5    344   PYRD_POLSQ Dihydroorotate dehydrogenase (quin...3050.000000000000002     79.3     26     46GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
139Q63707    395   PYRD_RAT Dihydroorotate dehydrogenase (quinon...3230.000000000000002     79.7     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
GO:0004158; F:dihydroorotate oxidase activity; IDA:RGD.::GO:0008144; F:drug binding; IPI:RGD.::GO:0010181; F:FMN binding; IDA:RGD.::GO:0048039; F:ubiquinone binding; IDA:RGD.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0007595; P:lactation; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0090140; P:regulation of mitochondrial fission; IMP:RGD.::GO:0031000; P:response to caffeine; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
140Q9F1U7    350   PYRD_FLALU Dihydroorotate dehydrogenase (quin...3160.000000000000004     78.2     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
141A7HQ77    348   PYRD_PARL1 Dihydroorotate dehydrogenase (quin...3170.000000000000005     77.8     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
142Q8X643    413   PREA_ECO57 NAD-dependent dihydropyrimidine de...2410.000000000000007     78.2     28     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004159; F:dihydrouracil dehydrogenase (NAD+) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003954; F:NADH dehydrogenase activity; ISS:UniProtKB.
GO:0006208; P:pyrimidine base catabolic process; ISS:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
143P25889    411   PREA_ECOLI NAD-dependent dihydropyrimidine de...2410.000000000000009     77.8     28     49GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004159; F:dihydrouracil dehydrogenase (NAD+) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003954; F:NADH dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:EcoCyc.
GO:0006928; P:cellular component movement; IMP:EcoCyc.::GO:0006208; P:pyrimidine base catabolic process; IDA:UniProtKB.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
144Q9HMK2    349   PYRD_HALSA Dihydroorotate dehydrogenase (quin...3330.000000000000009     77     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
145B0R808    349   PYRD_HALS3 Dihydroorotate dehydrogenase (quin...3330.000000000000009     77     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
146Q2N6N6    343   PYRD_ERYLH Dihydroorotate dehydrogenase (quin...3250.00000000000004     75.5     25     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
147Q30R79    352   PYRD_SULDN Dihydroorotate dehydrogenase (quin...2660.00000000000004     75.5     27     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
148B2IU79    376   PYRD_NOSP7 Dihydroorotate dehydrogenase (quin...2720.00000000000005     75.5     25     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
149A7NLW9    367   PYRD_ROSCS Dihydroorotate dehydrogenase (quin...2720.00000000000005     75.5     24     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
150C0ZZY4    356   PYRD_RHOE4 Dihydroorotate dehydrogenase (quin...2720.00000000000006     74.7     26     43GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
151A5IK84    270   PYRDB_THEP1 Dihydroorotate dehydrogenase B (N...2660.00000000000009     73.2     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.::GO:0004589; F:orotate reductase (NADH) activity; IEA:EC.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
records
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