Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL213C
Length:
715
Number of sequences:
5887
Description:
YKL213C DOA1 SGDID:S000001696, Chr XI from 34107-31960, Genome Release 64-1-1, reverse complement, Verified ORF, "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36037    715   DOA1_YEAST Protein DOA1 OS=Saccharomyces cere...7150     1465     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
2O94289    713   LUB1_SCHPO Ubiquitin homeostasis protein lub1...7063e-117     375     37     54GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0043130; F:ubiquitin binding; ISS:PomBase.
GO:0006281; P:DNA repair; ISS:PomBase.::GO:0016574; P:histone ubiquitination; NAS:PomBase.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:PomBase.
3P54319    795   PLAP_RAT Phospholipase A-2-activating protein...7948e-104     342     33     50
4P27612    794   PLAP_MOUSE Phospholipase A-2-activating prote...7909e-103     339     32     50
GO:0016005; F:phospholipase A2 activator activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006954; P:inflammatory response; IDA:MGI.
5Q9Y263    795   PLAP_HUMAN Phospholipase A-2-activating prote...7884e-101     334     32     49
GO:0016005; F:phospholipase A2 activator activity; TAS:ProtInc.
GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
6Q6GM65    799   PLAP_XENLA Phospholipase A-2-activating prote...7982e-94     316     31     48
GO:0005488; F:binding; IEA:InterPro.
7Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...1220.0002     48.1     26     49GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
8Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...2931e-17     91.3     29     48
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
9Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...880.082     40     28     51
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
10Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1360.034     41.2     24     46
11Q8N136    415   WDR69_HUMAN Outer row dynein assembly protein...1220.0004     47.4     26     48GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
12P38129    798   TAF5_YEAST Transcription initiation factor TF...2620.00000000002     71.2     28     42GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD.
13Q5FWQ6    415   WDR69_XENLA Outer row dynein assembly protein...610.002     45.1     41     59GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
14Q6P2Y2    415   WDR69_XENTR Outer row dynein assembly protein...610.001     45.4     41     59GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
15Q17963    376   TG125_CAEEL WD repeat-containing protein tag-...3055e-19     93.2     27     45GO:0005634; C:nucleus; IDA:WormBase.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051568; P:histone H3-K4 methylation; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
16Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...1730.0003     47.8     27     43
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
17Q09990    665   LIN23_CAEEL F-box/WD repeat-containing protei...1730.0002     48.5     26     46GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
18Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...1730.0003     47.8     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
19Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...1730.0003     47.8     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
20Q4R8E7    415   WDR69_MACFA Outer row dynein assembly protein...1220.0004     47.4     26     48GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
21Q5BK30    415   WDR69_RAT Outer row dynein assembly protein 1...610.004     43.9     41     57GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
22Q8VBV4    629   FBXW7_MOUSE F-box/WD repeat-containing protei...852     35.4     26     53GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
23Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...851.5     35.8     26     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
24Q05946    817   UTP13_YEAST U3 small nucleolar RNA-associated...2131     36.6     23     39GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; IPI:SGD.
GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
25Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...2010.00000000008     69.3     31     51
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
26A8X8C6    368   TG125_CAEBR WD repeat-containing protein tag-...3037e-18     89.4     25     47
27Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...1730.0002     48.1     27     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
28Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...1730.0002     48.1     27     43GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
29Q3Y8L7    446   WDR69_CHLRE Outer row dynein assembly protein...1890.00000001     61.6     25     41GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
30Q8HXX0    410   LIS1_MACFA Platelet-activating factor acetylh...1860.027     41.2     26     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
31Q1LV15    415   WDR69_DANRE Outer row dynein assembly protein...1260.0003     47.4     27     48GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
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