UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL213C

Length:

715

Number of sequences:

5887

Description:

YKL213C DOA1 SGDID:S000001696, Chr XI from 34107-31960, Genome Release 64-1-1, reverse complement, Verified ORF, "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
601	O43660	514	PLRG1_HUMAN Pleiotropic regulator 1 OS=Homo s...	177	0.002	45.1	29	45	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
602	O45040	340	GBB1_HOMAM Guanine nucleotide-binding protein...	124	3.3	34.3	30	45
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
603	Q562E7	890	WDR81_HUMAN WD repeat-containing protein 81 O...	208	0.0006	47	23	40
									GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
604	O14727	1248	APAF_HUMAN Apoptotic protease-activating fact...	100	0.47	37.7	29	50	GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
605	P26308	340	GBB1_DROME Guanine nucleotide-binding protein...	124	5	33.9	29	43	GO:0005875; C:microtubule associated complex; IDA:FlyBase.
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
									GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0045176; P:apical protein localization; TAS:FlyBase.::GO:0055059; P:asymmetric neuroblast division; IMP:FlyBase.
606	Q9VTV1	350	THOC6_DROME THO complex subunit 6 OS=Drosophi...	55	0.0007	46.2	42	55	GO:0000347; C:THO complex; IDA:UniProtKB.
									GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0009408; P:response to heat; IMP:UniProtKB.
607	P79959	340	GBB1_XENLA Guanine nucleotide-binding protein...	123	8.6	33.1	28	42
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
608	Q0DYP5	435	C3H17_ORYSJ Zinc finger CCCH domain-containin...	274	0.013	42.4	24	40
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
609	P16371	730	GROU_DROME Protein groucho OS=Drosophila mela...	177	0.0007	46.6	25	42	GO:0005634; C:nucleus; TAS:FlyBase.::GO:0043234; C:protein complex; IPI:FlyBase.
									GO:0071906; F:CRD domain binding; IPI:UniProtKB.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IGI:FlyBase.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IGI:FlyBase.
									GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0007541; P:sex determination, primary response to X:A ratio; TAS:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
610	B3NQR5	335	CIAO1_DROER Probable cytosolic iron-sulfur pr...	35	0.33	37.7	40	66
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
611	Q756D0	445	YTM1_ASHGO Ribosome biogenesis protein YTM1 O...	288	1.8	35.4	22	37	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
612	Q6CBI8	332	CIAO1_YARLI Probable cytosolic iron-sulfur pr...	270	0.084	39.3	24	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
613	Q54N86	1178	FBXAL_DICDI F-box/WD repeat-containing protei...	106	0.52	37.4	25	45
									GO:0005488; F:binding; IEA:InterPro.
614	P0CS44	757	MDV1_CRYNJ Mitochondrial division protein 1 O...	124	1.2	36.2	29	46	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
615	P0CS45	757	MDV1_CRYNB Mitochondrial division protein 1 O...	124	1.2	36.2	29	46	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
616	Q8IZU2	1322	WDR17_HUMAN WD repeat-containing protein 17 O...	236	0.0008	46.6	23	39
617	Q75C99	423	HAT2_ASHGO Histone acetyltransferase type B s...	122	3.6	34.3	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
618	Q54PP7	1154	LVSF_DICDI BEACH domain-containing protein lv...	109	0.46	37.7	30	46
619	P31146	461	COR1A_HUMAN Coronin-1A OS=Homo sapiens (Human...	222	0.001	45.8	25	42	GO:0005884; C:actin filament; IDA:UniProtKB.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001891; C:phagocytic cup; IDA:UniProtKB.::GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
									GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0045087; P:innate immune response; NAS:UniProtKB.::GO:0030595; P:leukocyte chemotaxis; IBA:RefGenome.::GO:0051126; P:negative regulation of actin nucleation; IDA:UniProtKB.::GO:0001845; P:phagolysosome assembly; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; IBA:RefGenome.::GO:0032796; P:uropod organization; IBA:RefGenome.
620	C5DY07	444	LIS1_ZYGRC Nuclear distribution protein PAC1 ...	190	3.1	34.7	24	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
621	Q9NSI6	2320	BRWD1_HUMAN Bromodomain and WD repeat-contain...	78	3.1	35	27	51	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
622	O43815	780	STRN_HUMAN Striatin OS=Homo sapiens (Human). ...	267	0.001	46.2	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; ISS:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB.
									GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
									GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0070830; P:tight junction assembly; NAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB.
623	O22785	525	PR19B_ARATH Pre-mRNA-processing factor 19 hom...	228	0.001	45.8	24	43	GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0042742; P:defense response to bacterium; IGI:TAIR.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
624	Q6KAU8	623	A16L2_MOUSE Autophagy-related protein 16-2 OS...	212	0.001	45.8	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
625	P57775	412	FBXW4_HUMAN F-box/WD repeat-containing protei...	183	0.025	41.2	24	45	GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB.
									GO:0030326; P:embryonic limb morphogenesis; NAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
626	Q94BM7	794	SPA4_ARATH Protein SPA1-RELATED 4 OS=Arabidop...	158	2.5	35	23	41	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.
									GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
627	A3LNI7	524	LIS1_PICST Nuclear distribution protein PAC1 ...	47	1.5	35.8	40	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
628	Q8N1V2	620	WDR16_HUMAN WD repeat-containing protein 16 O...	139	0.001	45.8	24	45	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
									GO:0005515; F:protein binding; IPI:UniProtKB.
629	Q95JL5	571	WDR16_MACFA WD repeat-containing protein 16 O...	139	0.001	45.8	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
630	O55106	780	STRN_MOUSE Striatin OS=Mus musculus (Mouse). ...	268	0.001	45.8	24	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
631	Q5ZJH5	305	WDR61_CHICK WD repeat-containing protein 61 O...	193	0.028	40.8	25	45	GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
									GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.

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