Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL213C
Length:
715
Number of sequences:
5887
Description:
YKL213C DOA1 SGDID:S000001696, Chr XI from 34107-31960, Genome Release 64-1-1, reverse complement, Verified ORF, "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...3200.000003     53.9     25     40GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
302Q20636    356   GBB2_CAEEL Guanine nucleotide-binding protein...1091     36.2     26     41GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007212; P:dopamine receptor signaling pathway; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IMP:WormBase.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IGI:WormBase.::GO:0040012; P:regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0032094; P:response to food; IMP:WormBase.
303Q9AUR8    1218   COPA1_ORYSJ Coatomer subunit alpha-1 OS=Oryza...3580.0000001     58.9     23     42GO:0030126; C:COPI vesicle coat; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
304Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...2770.00003     50.1     21     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
305P16649    713   TUP1_YEAST General transcriptional corepresso...2570.56     37.4     26     40GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
306Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...3200.000004     53.9     25     40GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
307Q7ZUV2    694   KTNB1_DANRE Katanin p80 WD40-containing subun...2520.0000002     58.5     25     47GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
308Q10282    305   GBB_SCHPO Guanine nucleotide-binding protein ...2080.0000002     57.4     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005834; C:heterotrimeric G-protein complex; TAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0010619; P:activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway; TAS:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
309D1ZEM6    486   LIS12_SORMK Nuclear distribution protein PAC1...1053.3     34.7     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
310Q8VEJ4    485   NLE1_MOUSE Notchless protein homolog 1 OS=Mus...1810.016     42     24     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0001826; P:inner cell mass cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.
311Q5SUS0    1030   FBW10_MOUSE F-box/WD repeat-containing protei...2450.0000002     58.5     23     42
312A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...3110.0002     48.9     23     39
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
313Q7S7L4    486   LIS12_NEUCR Nuclear distribution protein pac1...1053.4     34.7     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
314Q6BU94    417   PRP46_DEBHA Pre-mRNA-splicing factor PRP46 OS...2690.000002     54.7     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
315P53622    1201   COPA_YEAST Coatomer subunit alpha OS=Saccharo...3130.000004     53.9     22     42GO:0030126; C:COPI vesicle coat; IMP:SGD.
GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
316O62621    914   COPB2_DROME Coatomer subunit beta' OS=Drosoph...1320.013     42.7     27     47GO:0030126; C:COPI vesicle coat; NAS:UniProtKB.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0010883; P:regulation of lipid storage; IDA:FlyBase.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.
317Q9AUR7    1218   COPA2_ORYSJ Coatomer subunit alpha-2 OS=Oryza...3580.0000002     58.2     23     42GO:0030126; C:COPI vesicle coat; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
318B6HP56    458   LIS11_PENCW Nuclear distribution protein nudF...725.3     33.9     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
319Q58D20    485   NLE1_BOVIN Notchless protein homolog 1 OS=Bos...1810.005     43.9     25     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
320Q6PFM9    677   WDR48_DANRE WD repeat-containing protein 48 O...1540.007     43.5     24     46GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
321B7FNU7    439   LIS1_PHATC Lissencephaly-1 homolog OS=Phaeoda...1840.00007     49.7     26     44GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
322Q5ZMA2    505   PRP19_CHICK Pre-mRNA-processing factor 19 OS=...1050.0005     47     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
323B0X2V9    670   WDR48_CULQU WD repeat-containing protein 48 h...395.7     33.9     46     67
324Q6Q0C0    670   TRAF7_HUMAN E3 ubiquitin-protein ligase TRAF7...2740.0000003     57.8     26     44GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IDA:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
325Q8H0T9    837   KTNB1_ARATH Katanin p80 WD40 repeat-containin...1280.089     40     27     41GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.
326B7PY76    425   WDR12_IXOSC Ribosome biogenesis protein WDR12...1670.046     40.4     24     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
327Q9SJT9    1218   COPA2_ARATH Coatomer subunit alpha-2 OS=Arabi...3030.0000003     57.8     22     43GO:0030126; C:COPI vesicle coat; IEA:InterPro.::GO:0005829; C:cytosol; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
328Q2UGU1    455   LIS1_ASPOR Nuclear distribution protein nudF ...1990.00001     52     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
329B8N9H4    455   LIS1_ASPFN Nuclear distribution protein nudF ...1990.00001     52     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
330Q9UTC7    462   YIDC_SCHPO Uncharacterized WD repeat-containi...1880.056     40.4     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
331Q9AV81    527   PUB72_ORYSJ U-box domain-containing protein 7...2480.0000004     57     26     44GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
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