Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL212W
Length:
623
Number of sequences:
5887
Description:
YKL212W SAC1 SGDID:S000001695, Chr XI from 34543-36414, Genome Release 64-1-1, Verified ORF, "Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32368    623   SAC1_YEAST Phosphoinositide phosphatase SAC1 ...6230     1297     100     100GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0030173; C:integral to Golgi membrane; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.
2O60162    598   YG23_SCHPO Uncharacterized protein C19F5.03 O...5691e-151     457     43     60GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.::GO:0030173; C:integral to Golgi membrane; ISS:PomBase.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase.
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0016192; P:vesicle-mediated transport; ISS:PomBase.
3A1L244    586   SAC1A_DANRE Phosphatidylinositide phosphatase...5556e-122     380     38     56GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
4A4VCH0    586   SAC1B_DANRE Phosphatidylinositide phosphatase...5835e-120     375     36     55GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
5Q9ES21    587   SAC1_RAT Phosphatidylinositide phosphatase SA...5842e-115     363     36     54GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:RGD.
GO:0034593; F:phosphatidylinositol bisphosphate phosphatase activity; IDA:RGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:RGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:RGD.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.
6A6QL88    587   SAC1_BOVIN Phosphatidylinositide phosphatase ...5842e-115     363     36     55GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
7Q6GM29    586   SAC1_XENLA Phosphatidylinositide phosphatase ...5845e-115     362     36     55GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
8Q9W0I6    592   SAC1_DROME Phosphatidylinositide phosphatase ...5802e-114     361     38     55GO:0030424; C:axon; IDA:FlyBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:FlyBase.::GO:0071683; C:sensory dendrite; IDA:FlyBase.
GO:0052866; F:phosphatidylinositol phosphate phosphatase activity; IDA:FlyBase.
GO:0016199; P:axon midline choice point recognition; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0046329; P:negative regulation of JNK cascade; IMP:FlyBase.
9Q5R921    587   SAC1_PONAB Phosphatidylinositide phosphatase ...5843e-114     360     36     54GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
10Q9NTJ5    587   SAC1_HUMAN Phosphatidylinositide phosphatase ...5843e-114     360     36     54GO:0005794; C:Golgi apparatus; IDA:LIFEdb.
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
11Q9EP69    587   SAC1_MOUSE Phosphatidylinositide phosphatase ...5844e-114     360     36     54
GO:0016791; F:phosphatase activity; ISS:UniProtKB.
12O14127    611   YF51_SCHPO Uncharacterized protein C3C7.01c O...5782e-94     309     35     51GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0000139; C:Golgi membrane; ISS:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.
13Q55AW9    581   SAC1_DICDI Phosphatidylinositide phosphatase ...5535e-80     270     35     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; ISS:dictyBase.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:dictyBase.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; ISS:dictyBase.
GO:0048017; P:inositol lipid-mediated signaling; ISS:dictyBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:dictyBase.
14Q8CDA1    1132   SAC2_MOUSE Phosphatidylinositide phosphatase ...4202e-78     274     37     56
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
15A8E7C5    1120   SAC2_DANRE Phosphatidylinositide phosphatase ...4354e-78     273     36     55
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
16Q9Y2H2    1132   SAC2_HUMAN Phosphatidylinositide phosphatase ...4206e-77     270     37     55
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
17Q12271    1107   INP53_YEAST Polyphosphatidylinositol phosphat...5647e-57     212     29     50GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD.
GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
18P50942    1183   INP52_YEAST Polyphosphatidylinositol phosphat...4082e-54     205     33     52GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD.
GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
19O43001    1076   SYJ1_SCHPO Inositol-1,4,5-trisphosphate 5-pho...4112e-47     183     34     50GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.
GO:0006897; P:endocytosis; NAS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
20Q8CHC4    1574   SYNJ1_MOUSE Synaptojanin-1 OS=Mus musculus (M...4913e-42     168     29     47GO:0030118; C:clathrin coat; TAS:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI.::GO:0016191; P:synaptic vesicle uncoating; IMP:MGI.
21Q91WF7    907   FIG4_MOUSE Polyphosphoinositide phosphatase O...5724e-42     167     26     44GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0048666; P:neuron development; IMP:MGI.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:MGI.::GO:0043473; P:pigmentation; IMP:MGI.::GO:0007033; P:vacuole organization; IMP:MGI.
22O43426    1573   SYNJ1_HUMAN Synaptojanin-1 OS=Homo sapiens (H...4915e-42     167     29     47
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
23Q62910    1574   SYNJ1_RAT Synaptojanin-1 OS=Rattus norvegicus...4915e-42     167     29     47GO:0019717; C:synaptosome; IDA:RGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IDA:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0014015; P:positive regulation of gliogenesis; IMP:RGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0032526; P:response to retinoic acid; IMP:RGD.
24P42837    879   FIG4_YEAST Polyphosphoinositide phosphatase O...4871e-40     162     29     45GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0070772; C:PAS complex; IDA:SGD.
GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.
25Q92562    907   FIG4_HUMAN Polyphosphoinositide phosphatase O...5183e-40     161     26     45GO:0010008; C:endosome membrane; IDA:UniProtKB.
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008219; P:cell death; IEA:UniProtKB-KW.
26O18964    1324   SYNJ1_BOVIN Synaptojanin-1 OS=Bos taurus (Bov...4871e-39     160     29     47GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
27O15056    1496   SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens (H...5283e-39     159     28     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
28Q9D2G5    1434   SYNJ2_MOUSE Synaptojanin-2 OS=Mus musculus (M...5182e-37     153     28     46
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
29O55207    1496   SYNJ2_RAT Synaptojanin-2 OS=Rattus norvegicus...5161e-36     150     28     45GO:0043679; C:axon terminus; IDA:RGD.::GO:0005881; C:cytoplasmic microtubule; IDA:RGD.::GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0032587; C:ruffle membrane; IDA:RGD.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0052744; F:phosphatidylinositol monophosphate phosphatase activity; IDA:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:RGD.::GO:0048312; P:intracellular distribution of mitochondria; IDA:RGD.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
30Q7Z9H9    832   FIG4_SCHPO Polyphosphoinositide phosphatase O...4872e-36     149     27     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0019898; C:extrinsic to membrane; ISS:PomBase.::GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.
GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; ISS:PomBase.::GO:0046488; P:phosphatidylinositol metabolic process; NAS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.
31Q9USQ6    889   SYJ2_SCHPO Inositol-1,4,5-trisphosphate 5-pho...4426e-28     123     24     47GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; ISS:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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