Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL193C
Length:
338
Number of sequences:
5887
Description:
YKL193C SDS22 SGDID:S000001676, Chr XI from 79882-78866, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P24014    1504   SLIT_DROME Protein slit OS=Drosophila melanog...1220.34     36.6     28     48GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0005578; C:proteinaceous extracellular matrix; TAS:FlyBase.::GO:0071666; C:Slit-Robo signaling complex; IDA:FlyBase.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008201; F:heparin binding; IDA:FlyBase.::GO:0048495; F:Roundabout binding; IPI:FlyBase.
GO:0016199; P:axon midline choice point recognition; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0007502; P:digestive tract mesoderm development; IMP:FlyBase.::GO:0035050; P:embryonic heart tube development; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:UniProtKB.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0050929; P:induction of negative chemotaxis; IMP:UniProtKB.::GO:0008078; P:mesodermal cell migration; IMP:FlyBase.::GO:0001764; P:neuron migration; IMP:FlyBase.::GO:0003151; P:outflow tract morphogenesis; IMP:FlyBase.::GO:0022409; P:positive regulation of cell-cell adhesion; IMP:FlyBase.::GO:2000274; P:regulation of epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0035385; P:Roundabout signaling pathway; IGI:FlyBase.::GO:0007432; P:salivary gland boundary specification; IMP:FlyBase.
182Q9D5E4    523   LRC48_MOUSE Leucine-rich repeat-containing pr...1310.001     43.9     34     52
183Q8INT5    1483   DAAF1_DROME Dynein assembly factor 1, axonema...1000.0008     45.1     36     57GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:FlyBase.
184Q8CBC6    707   LRRN3_MOUSE Leucine-rich repeat neuronal prot...2510.001     44.3     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
185O75094    1523   SLIT3_HUMAN Slit homolog 3 protein OS=Homo sa...1241.4     34.7     29     47GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005739; C:mitochondrion; NAS:UniProtKB.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0048495; F:Roundabout binding; IPI:UniProtKB.
GO:0061364; P:apoptotic process involved in luteolysis; IEP:UniProtKB.::GO:0048846; P:axon extension involved in axon guidance; IDA:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.::GO:0050919; P:negative chemotaxis; IDA:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IMP:BHF-UCL.::GO:0051414; P:response to cortisol stimulus; IEP:UniProtKB.::GO:0035385; P:Roundabout signaling pathway; IMP:BHF-UCL.
186Q8BXA0    719   LRFN5_MOUSE Leucine-rich repeat and fibronect...1690.000001     53.5     34     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
187D4A1J9    719   LRFN5_RAT Leucine-rich repeat and fibronectin...1690.000001     53.5     34     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
188Q3V1M1    2594   IGS10_MOUSE Immunoglobulin superfamily member...1540.00001     50.8     29     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro.
GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro.
189F1MCA7    1536   LRRC7_BOVIN Leucine-rich repeat-containing pr...2040.5     36.2     27     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
190Q96NI6    719   LRFN5_HUMAN Leucine-rich repeat and fibronect...1690.000002     53.5     34     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
191Q3ZC49    334   LRC39_BOVIN Leucine-rich repeat-containing pr...2212.6     33.5     25     39
192Q9TSP2    826   TLR4_PAPAN Toll-like receptor 4 OS=Papio anub...2222.9     33.5     24     41GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB.
GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB.
193Q5XI54    523   LRC48_RAT Leucine-rich repeat-containing prot...820.006     42     40     57
194Q9CZ62    856   CEP97_MOUSE Centrosomal protein of 97 kDa OS=...1820.002     43.5     23     49
195P19879    299   MIME_BOVIN Mimecan OS=Bos taurus (Bovine). GN...1790.000002     52.4     30     46GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
196O70210    358   CHAD_RAT Chondroadherin OS=Rattus norvegicus ...2600.000002     52.8     27     46GO:0005578; C:proteinaceous extracellular matrix; TAS:RGD.
GO:0001502; P:cartilage condensation; IEP:RGD.
197Q3UVD5    967   LGR6_MOUSE Leucine-rich repeat-containing G-p...2450.0007     45.1     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
198Q29KL8    1582   DAAF1_DROPS Dynein assembly factor 1, axonema...590.1     38.5     41     61GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
199Q5R1V9    359   PGS2_PANTR Decorin OS=Pan troglodytes (Chimpa...1790.007     41.6     31     50GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
200P07585    359   PGS2_HUMAN Decorin OS=Homo sapiens (Human). G...1790.007     41.6     31     50GO:0005615; C:extracellular space; IDA:BHF-UCL.
GO:0009887; P:organ morphogenesis; TAS:ProtInc.
201Q80TM9    1593   NISCH_MOUSE Nischarin OS=Mus musculus (Mouse)...1500.00009     48.1     28     48GO:0005829; C:cytosol; IDA:MGI.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005178; F:integrin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.
202P35858    605   ALS_HUMAN Insulin-like growth factor-binding ...2590.0002     46.2     25     44GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005520; F:insulin-like growth factor binding; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
203B3DH20    440   TILB_DANRE Protein TILB homolog OS=Danio reri...1412.7     33.5     30     46GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
204Q9BXN1    380   ASPN_HUMAN Asporin OS=Homo sapiens (Human). G...2370.071     38.5     24     46GO:0005578; C:proteinaceous extracellular matrix; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.
GO:0030282; P:bone mineralization; IDA:UniProtKB.::GO:0070171; P:negative regulation of tooth mineralization; ISS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
205Q9TTE2    360   PGS2_SHEEP Decorin OS=Ovis aries (Sheep). GN=...1770.021     40     31     51GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
206P21793    360   PGS2_BOVIN Decorin OS=Bos taurus (Bovine). GN...1770.02     40     31     51GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
207O00206    839   TLR4_HUMAN Toll-like receptor 4 OS=Homo sapie...1830.000002     52.8     33     50GO:0009897; C:external side of plasma membrane; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0046696; C:lipopolysaccharide receptor complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.::GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.::GO:0016046; P:detection of fungus; NAS:UniProtKB.::GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0060729; P:intestinal epithelial structure maintenance; ISS:BHF-UCL.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.::GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.::GO:0032707; P:negative regulation of interleukin-23 production; ISS:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.::GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:BHF-UCL.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.::GO:0032732; P:positive regulation of interleukin-1 production; ISS:BHF-UCL.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0042088; P:T-helper 1 type immune response; NAS:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
208B4GT53    1501   DAAF1_DROPE Dynein assembly factor 1, axonema...590.11     38.1     41     61GO:0035085; C:cilium axoneme; ISS:UniProtKB.
GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
209Q3ZBN5    370   ASPN_BOVIN Asporin OS=Bos taurus (Bovine). GN...2370.002     43.1     24     46GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
210Q9TTN0    839   TLR4_PANPA Toll-like receptor 4 OS=Pan panisc...1830.000003     52.8     33     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0046696; C:lipopolysaccharide receptor complex; ISS:UniProtKB.
GO:0001875; F:lipopolysaccharide receptor activity; ISS:UniProtKB.::GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO:0032497; P:detection of lipopolysaccharide; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0042116; P:macrophage activation; ISS:UniProtKB.
211Q24K06    278   LRC10_BOVIN Leucine-rich repeat-containing pr...1910.000003     51.6     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
records
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