UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL182W

Length:

2051

Number of sequences:

5887

Description:

YKL182W FAS1 SGDID:S000001665, Chr XI from 100671-106826, Genome Release 64-1-1, Verified ORF, "Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P07149	2051	FAS1_YEAST Fatty acid synthase subunit beta O...	2051	0	4237	100	100	GO:0005835; C:fatty acid synthase complex; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IDA:SGD.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IDA:SGD.::GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IDA:SGD.::GO:0004321; F:fatty-acyl-CoA synthase activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016409; F:palmitoyltransferase activity; IDA:SGD.]::GO:0005515; F:protein binding; IPI:IntAct.]
									GO:0006633; P:fatty acid biosynthetic process; IMP:SGD.]
2	P34731	2037	FAS1_CANAX Fatty acid synthase subunit beta O...	2060	0	2625	62	77	GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0004321; F:fatty-acyl-CoA synthase activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
3	P34229	2086	FAS1_YARLI Fatty acid synthase subunit beta O...	2075	0	2460	58	74	GO:0005835; C:fatty acid synthase complex; NAS:UniProtKB.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0004321; F:fatty-acyl-CoA synthase activity; NAS:UniProtKB.::GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]
									GO:0006633; P:fatty acid biosynthetic process; NAS:UniProtKB.]
4	Q9UUG0	2073	FAS1_SCHPO Fatty acid synthase subunit beta O...	2099	0	1966	48	66	GO:0005835; C:fatty acid synthase complex; IDA:PomBase.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; ISS:PomBase.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; ISS:PomBase.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; ISS:PomBase.::GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:PomBase.::GO:0004321; F:fatty-acyl-CoA synthase activity; TAS:PomBase.::GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]
									GO:0006633; P:fatty acid biosynthetic process; ISS:PomBase.]
5	Q92215	2080	TOXC_COCCA Putative fatty acid synthase subun...	2078	0	1813	45	63	GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
6	Q00706	1914	STCK_EMENI Putative sterigmatocystin biosynth...	1984	0	1123	35	53	GO:0005835; C:fatty acid synthase complex; IEA:InterPro.
									GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
7	P71019	317	FABD_BACSU Malonyl CoA-acyl carrier protein t...	241	0.091	40.8	24	40
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
8	Q6GHK5	308	FABD_STAAR Malonyl CoA-acyl carrier protein t...	182	0.0000003	58.2	29	39
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
9	Q93QD4	308	FABD_STAAU Malonyl CoA-acyl carrier protein t...	182	0.0000008	57	29	39
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
10	Q5HGK3	308	FABD_STAAC Malonyl CoA-acyl carrier protein t...	182	0.0000008	57	29	39
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
11	Q54KU3	2380	PKS25_DICDI Probable polyketide synthase 25 O...	200	0.000001	57.8	26	44
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
12	Q54KU5	2471	PKS24_DICDI Probable polyketide synthase 24 O...	182	0.000001	57.8	25	43
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
13	Q6G9Y3	308	FABD_STAAS Malonyl CoA-acyl carrier protein t...	182	0.000004	54.7	28	38
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
14	Q7A124	308	FABD_STAAW Malonyl CoA-acyl carrier protein t...	182	0.000004	54.7	28	38
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
15	Q7A5Z3	308	FABD_STAAN Malonyl CoA-acyl carrier protein t...	182	0.000004	54.7	28	38
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
16	Q99UN8	308	FABD_STAAM Malonyl CoA-acyl carrier protein t...	182	0.000004	54.7	28	38
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
17	P51660	735	DHB4_MOUSE Peroxisomal multifunctional enzyme...	133	0.000006	55.1	32	47	GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IDA:MGI.
									GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0032934; F:sterol binding; IEA:InterPro.
									GO:0006635; P:fatty acid beta-oxidation; IMP:MGI.::GO:0060009; P:Sertoli cell development; IMP:MGI.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:MGI.
18	P51659	736	DHB4_HUMAN Peroxisomal multifunctional enzyme...	133	0.000006	55.1	30	48	GO:0005782; C:peroxisomal matrix; TAS:Reactome.
									GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.
									GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
19	P97852	735	DHB4_RAT Peroxisomal multifunctional enzyme t...	133	0.00004	52.8	30	47	GO:0005777; C:peroxisome; IDA:HGNC.
									GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; TAS:RGD.
									GO:0008203; P:cholesterol metabolic process; NAS:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.]
20	Q54IX3	2531	PKS26_DICDI Probable polyketide synthase 26 O...	177	0.00004	52.8	23	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
21	Q869W9	2603	PKS16_DICDI Probable polyketide synthase 16 O...	179	0.00005	52.4	24	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
22	Q55DM7	3010	PKS2_DICDI Probable polyketide synthase 2 OS=...	241	0.0001	51.2	24	40
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
23	O34825	288	PKSC_BACSU Polyketide biosynthesis malonyl Co...	218	0.0002	48.9	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.]
24	B0G101	2514	PKS8_DICDI Probable polyketide synthase 8/35 ...	259	0.0005	49.3	24	39
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
25	Q558W4	3174	PKS15_DICDI Probable polyketide synthase 15 O...	208	0.0005	49.3	23	38
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
26	P0AAI9	309	FABD_ECOLI Malonyl CoA-acyl carrier protein t...	94	0.062	41.6	31	51
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
27	P0AAJ0	309	FABD_ECOL6 Malonyl CoA-acyl carrier protein t...	94	0.062	41.6	31	51
									GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
28	B0G0Z9	2924	PKS6_DICDI Probable polyketide synthase 6 OS=...	259	0.001	48.1	23	38	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
29	Q86AE3	2931	PKS9_DICDI Probable polyketide synthase 9/36 ...	259	0.001	47.8	23	38	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
30	P96285	1616	PKS1_MYCTU Putative inactive phenolphthiocero...	127	0.001	47.8	32	50	GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0071770; P:DIM/DIP cell wall layer assembly; IMP:MTBBASE.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IMP:MTBBASE.
31	Q559A9	2551	PKS13_DICDI Probable polyketide synthase 13 O...	57	0.001	47.8	39	56
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.

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