UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL181W

Length:

427

Number of sequences:

5887

Description:

YKL181W PRS1 SGDID:S000001664, Chr XI from 107316-108599, Genome Release 64-1-1, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P32895	427	KPR1_YEAST Ribose-phosphate pyrophosphokinase...	427	0	879	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
2	P41831	409	KPR1_SCHPO Ribose-phosphate pyrophosphokinase...	421	3e-142	419	50	69	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
									GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
3	P60892	318	PRPS1_RAT Ribose-phosphate pyrophosphokinase ...	112	3e-18	88.6	43	63	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
4	Q5RFJ7	318	PRPS1_PONAB Ribose-phosphate pyrophosphokinas...	112	3e-18	88.6	43	63
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
5	Q9D7G0	318	PRPS1_MOUSE Ribose-phosphate pyrophosphokinas...	112	3e-18	88.6	43	63
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
6	P60891	318	PRPS1_HUMAN Ribose-phosphate pyrophosphokinas...	112	3e-18	88.6	43	63	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; IDA:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; TAS:Reactome.::GO:0046101; P:hypoxanthine biosynthetic process; IMP:UniProtKB.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IMP:UniProtKB.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; NAS:UniProtKB.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0034418; P:urate biosynthetic process; IMP:UniProtKB.
7	Q2HJ58	318	PRPS1_BOVIN Ribose-phosphate pyrophosphokinas...	112	3e-18	88.6	43	63
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
8	Q4R4U3	318	PRPS1_MACFA Ribose-phosphate pyrophosphokinas...	112	3e-18	88.2	43	63
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
9	Q5XGI0	318	PRPS2_XENTR Ribose-phosphate pyrophosphokinas...	112	2e-19	91.7	45	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
10	P21108	318	PRPS3_HUMAN Ribose-phosphate pyrophosphokinas...	112	2e-17	85.9	44	62
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; NAS:UniProtKB.
11	Q5R8F8	318	PRPS2_PONAB Ribose-phosphate pyrophosphokinas...	112	3e-19	91.3	45	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
12	Q4R4R7	318	PRPS2_MACFA Ribose-phosphate pyrophosphokinas...	112	3e-19	91.3	45	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
13	P11908	318	PRPS2_HUMAN Ribose-phosphate pyrophosphokinas...	112	3e-19	91.3	45	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
14	Q7ZXC9	318	PRPS2_XENLA Ribose-phosphate pyrophosphokinas...	112	6e-20	93.2	46	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
15	Q9CS42	318	PRPS2_MOUSE Ribose-phosphate pyrophosphokinas...	112	2e-19	91.7	46	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
16	P09330	318	PRPS2_RAT Ribose-phosphate pyrophosphokinase ...	112	3e-19	91.3	45	64	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
17	O94413	321	KPR2_SCHPO Ribose-phosphate pyrophosphokinase...	112	6e-21	96.3	48	69	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
18	P38063	326	KPR4_YEAST Ribose-phosphate pyrophosphokinase...	112	2e-17	86.3	43	63	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
19	P38620	318	KPR2_YEAST Ribose-phosphate pyrophosphokinase...	110	0.000000000000001	80.5	43	62	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
20	Q5ZI49	325	PRPS2_CHICK Ribose-phosphate pyrophosphokinas...	112	8e-20	93.2	46	64
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
21	P46585	321	KPR1_CANAX Ribose-phosphate pyrophosphokinase...	112	0.000000000000007	78.6	42	60
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
22	P38689	320	KPR3_YEAST Ribose-phosphate pyrophosphokinase...	112	3e-18	88.2	46	61	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
23	P87171	341	KPR5_SCHPO Ribose-phosphate pyrophosphokinase...	113	1e-19	92.8	45	65	GO:0005737; C:cytoplasm; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; ISS:PomBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
24	Q54PA9	317	PRPSA_DICDI Ribose-phosphate pyrophosphokinas...	112	1e-20	95.1	44	68	GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
25	Q28DH0	358	KPRB_XENTR Phosphoribosyl pyrophosphate synth...	127	0.000000000000005	79.3	44	69
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
26	O60256	369	KPRB_HUMAN Phosphoribosyl pyrophosphate synth...	178	4e-17	85.9	40	60
									GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
27	Q5ZL26	369	KPRB_CHICK Phosphoribosyl pyrophosphate synth...	178	2e-16	83.6	40	58
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
28	O08618	369	KPRB_RAT Phosphoribosyl pyrophosphate synthas...	178	1e-16	84.7	40	60	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
29	Q5RBA8	369	KPRB_PONAB Phosphoribosyl pyrophosphate synth...	178	8e-17	85.1	40	60
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
30	Q8R574	369	KPRB_MOUSE Phosphoribosyl pyrophosphate synth...	178	1e-16	84.7	40	60
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
31	A2VDS0	369	KPRB_BOVIN Phosphoribosyl pyrophosphate synth...	178	0.000000000000001	81.3	39	59
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
									GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.

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