Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL181W
Length:
427
Number of sequences:
5887
Description:
YKL181W PRS1 SGDID:S000001664, Chr XI from 107316-108599, Genome Release 64-1-1, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31A2VDS0    369   KPRB_BOVIN Phosphoribosyl pyrophosphate synth...1780.000000000000001     81.3     39     59
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
32Q54QU9    321   PRPSC_DICDI Ribose-phosphate pyrophosphokinas...1130.0000000008     63.5     34     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
33Q97E93    319   KPRS_CLOAB Ribose-phosphate pyrophosphokinase...1141e-18     89.4     41     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
34Q7NM67    332   KPRS_GLOVI Ribose-phosphate pyrophosphokinase...1150.000000000001     72     37     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
35Q9D0M1    356   KPRA_MOUSE Phosphoribosyl pyrophosphate synth...1270.000000000000002     80.5     44     69
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
36Q14558    356   KPRA_HUMAN Phosphoribosyl pyrophosphate synth...1270.000000000000002     80.5     43     70
GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
37Q08DW2    356   KPRA_BOVIN Phosphoribosyl pyrophosphate synth...1270.000000000000003     80.1     43     70
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
38Q8XHJ4    319   KPRS_CLOPE Ribose-phosphate pyrophosphokinase...1150.0000000000008     72.4     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
39Q92N73    310   KPRS_RHIME Ribose-phosphate pyrophosphokinase...1150.00000002     59.3     27     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
40Q63468    356   KPRA_RAT Phosphoribosyl pyrophosphate synthas...1270.000000000000002     80.9     45     69GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0030234; F:enzyme regulator activity; IMP:RGD.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0009165; P:nucleotide biosynthetic process; TAS:RGD.
41P42816    315   KPRS_BACCL Ribose-phosphate pyrophosphokinase...1150.000000000000006     78.6     38     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
42Q8R753    316   KPRS_THETN Ribose-phosphate pyrophosphokinase...1141e-17     86.7     39     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
43B7IFM5    316   KPRS_THEAB Ribose-phosphate pyrophosphokinase...1140.0000003     55.5     30     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
44Q7M8J0    309   KPRS_WOLSU Ribose-phosphate pyrophosphokinase...1143e-18     88.2     40     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
45P14193    317   KPRS_BACSU Ribose-phosphate pyrophosphokinase...1140.000000000000009     78.2     38     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
46Q75JN8    329   PRPSB_DICDI Ribose-phosphate pyrophosphokinas...1540.00001     50.4     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
47Q8UDA9    310   KPRS_AGRT5 Ribose-phosphate pyrophosphokinase...1150.001     43.9     29     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
48P56184    318   KPRS_HELPY Ribose-phosphate pyrophosphokinase...1140.000000000000007     78.6     35     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
49Q7U7L5    331   KPRS_SYNPX Ribose-phosphate pyrophosphokinase...1120.00000000000004     76.6     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
50Q49V09    321   KPRS_STAS1 Ribose-phosphate pyrophosphokinase...1150.00000005     58.2     39     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
51Q9ZLA1    318   KPRS_HELPJ Ribose-phosphate pyrophosphokinase...1140.0000000000001     75.1     34     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
52Q8RHM2    316   KPRS_FUSNN Ribose-phosphate pyrophosphokinase...1150.000000000002     71.2     35     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
53Q899I8    320   KPRS_CLOTE Ribose-phosphate pyrophosphokinase...1150.00000000000002     77.4     37     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
54Q9HVC5    313   KPRS_PSEAE Ribose-phosphate pyrophosphokinase...1200.000000000000002     80.5     37     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
55Q7VBH4    327   KPRS_PROMA Ribose-phosphate pyrophosphokinase...1140.000000000005     70.1     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
56Q6AJL7    313   KPRS_DESPS Ribose-phosphate pyrophosphokinase...1100.000000000000005     79     39     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
57Q888C6    313   KPRS_PSESM Ribose-phosphate pyrophosphokinase...1141e-16     83.6     39     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
58Q88Z84    326   KPRS1_LACPL Ribose-phosphate pyrophosphokinas...1150.0000000002     65.1     33     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
59Q88PX6    313   KPRS_PSEPK Ribose-phosphate pyrophosphokinase...1143e-17     85.5     39     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
60Q8Y2E1    316   KPRS_RALSO Ribose-phosphate pyrophosphokinase...1140.00000000001     68.6     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
61Q7UPM4    316   KPRS_RHOBA Ribose-phosphate pyrophosphokinase...1361e-18     89.7     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
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