Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL173W
Length:
1008
Number of sequences:
5887
Description:
YKL173W SNU114 SGDID:S000001656, Chr XI from 122517-125543, Genome Release 64-1-1, Verified ORF, "GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36048    1008   SN114_YEAST Pre-mRNA-splicing factor SNU114 O...10080     2065     100     100GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
GO:0005525; F:GTP binding; ISS:SGD.::GO:0003924; F:GTPase activity; IMP:SGD.::GO:0030623; F:U5 snRNA binding; IDA:SGD.
GO:0000244; P:assembly of spliceosomal tri-snRNP; IMP:SGD.::GO:0000388; P:spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); IMP:SGD.
2O94316    983   SN114_SCHPO Pre-mRNA-splicing factor cwf10 OS...10561e-173     540     35     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0005525; F:GTP binding; ISS:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IC:PomBase.
3Q15029    972   U5S1_HUMAN 116 kDa U5 small nuclear ribonucle...10127e-167     522     34     52GO:0015030; C:Cajal body; IDA:BHF-UCL.::GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
4Q5F3X4    972   U5S1_CHICK 116 kDa U5 small nuclear ribonucle...10121e-166     521     34     52GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5O08810    971   U5S1_MOUSE 116 kDa U5 small nuclear ribonucle...9412e-166     521     35     53GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
6A4FUD3    972   U5S1_BOVIN 116 kDa U5 small nuclear ribonucle...10125e-166     520     34     52GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
7Q5R6E0    972   U5S1_PONAB 116 kDa U5 small nuclear ribonucle...10129e-166     519     34     52GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
8Q90705    858   EF2_CHICK Elongation factor 2 OS=Gallus gallu...9207e-96     329     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
9Q96X45    844   EF2_NEUCR Elongation factor 2 OS=1257 / FGSC ...9098e-92     317     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
10Q5R8Z3    858   EF2_PONAB Elongation factor 2 OS=Pongo abelii...9201e-91     317     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
11P13639    858   EF2_HUMAN Elongation factor 2 OS=Homo sapiens...9201e-91     317     27     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
12Q3SYU2    858   EF2_BOVIN Elongation factor 2 OS=Bos taurus (...9181e-91     317     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
13P05197    858   EF2_RAT Elongation factor 2 OS=Rattus norvegi...9182e-91     316     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; TAS:RGD.
14P58252    858   EF2_MOUSE Elongation factor 2 OS=Mus musculus...9182e-91     316     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
15A0SXL6    858   EF2_CALJA Elongation factor 2 OS=Callithrix j...9182e-91     316     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
16P09445    858   EF2_CRIGR Elongation factor 2 OS=Cricetulus g...9183e-91     316     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
17Q874B9    842   EF2_PICPA Elongation factor 2 OS=Pichia pasto...9149e-90     311     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
18P15112    839   EF2_DICDI Elongation factor 2 OS=Dictyosteliu...9002e-89     310     28     47GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
GO:0009617; P:response to bacterium; IEP:dictyBase.
19Q875Z2    842   EF2_NAUCC Elongation factor 2 OS=Y-12630) (Ye...9057e-89     309     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
20Q6CPQ9    842   EF2_KLULA Elongation factor 2 OS=1267 / NRRL ...9071e-88     308     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
21Q754C8    842   EF2_ASHGO Elongation factor 2 OS=Y-1056) (Yea...9072e-88     308     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
22P13060    844   EF2_DROME Elongation factor 2 OS=Drosophila m...9036e-88     306     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.
23A5DI11    842   EF2_PICGU Elongation factor 2 OS=1539 / NBRC ...8958e-88     306     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
24Q6BJ25    842   EF2_DEBHA Elongation factor 2 OS=0083 / IGC 2...9158e-88     306     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
25Q6FYA7    842   EF2_CANGA Elongation factor 2 OS=NRRL Y-65) (...9029e-88     306     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
26P32324    842   EF2_YEAST Elongation factor 2 OS=Saccharomyce...9071e-87     305     27     47GO:0005840; C:ribosome; TAS:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003746; F:translation elongation factor activity; TAS:SGD.
GO:0045901; P:positive regulation of translational elongation; IMP:SGD.
27Q23716    832   EF2_CRYPV Elongation factor 2 OS=Cryptosporid...8993e-87     304     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
28Q875S0    842   EF2_LACKL Elongation factor 2 OS=Lachancea kl...9075e-87     304     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
29P29691    852   EF2_CAEEL Elongation factor 2 OS=Caenorhabdit...9271e-86     303     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.
30Q1HPK6    844   EF2_BOMMO Translation elongation factor 2 OS=...9036e-86     301     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
31Q5A0M4    842   EF2_CANAL Elongation factor 2 OS=Candida albi...8944e-84     295     27     47GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0005625; C:soluble fraction; IDA:CGD.::GO:0030445; C:yeast-form cell wall; IDA:CGD.
GO:0008144; F:drug binding; IDA:CGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:CGD.::GO:0003746; F:translation elongation factor activity; IMP:CGD.
GO:0035690; P:cellular response to drug; IDA:CGD.
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