Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL171W
Length:
928
Number of sequences:
5887
Description:
YKL171W NNK1 SGDID:S000001654, Chr XI from 127475-130261, Genome Release 64-1-1, Verified ORF, "Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q84SN3    433   CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Or...1590.00007     50.1     27     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
542O22932    435   CIPKB_ARATH CBL-interacting serine/threonine-...1710.00007     50.1     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009268; P:response to pH; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
543Q9VKN7    329   AURKB_DROME Aurora kinase B OS=Drosophila mel...1270.00007     49.7     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0000776; C:kinetochore; TAS:FlyBase.::GO:0030496; C:midbody; IDA:FlyBase.::GO:0051233; C:spindle midzone; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0016572; P:histone phosphorylation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007076; P:mitotic chromosome condensation; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
544Q9V3D5    722   DYRK2_DROME Dual specificity tyrosine-phospho...1670.00007     50.4     25     48GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0042048; P:olfactory behavior; IMP:FlyBase.
545Q3TZA2    342   CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS...1560.00007     49.7     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
546Q91727    319   CDK4_XENLA Cyclin-dependent kinase 4 OS=Xenop...1620.00007     49.7     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
547Q14012    370   KCC1A_HUMAN Calcium/calmodulin-dependent prot...1610.00007     49.7     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.::GO:0043393; P:regulation of protein binding; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
548Q875L0    358   HOG1_CRYPA Mitogen-activated protein kinase H...1550.00008     49.7     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
549Q54WW7    695   Y0010_DICDI Probable serine/threonine-protein...1730.00008     50.1     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
550Q5Z859    369   MPK4_ORYSJ Mitogen-activated protein kinase 4...1660.00008     49.7     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
551P53778    367   MK12_HUMAN Mitogen-activated protein kinase 1...1620.00008     49.7     26     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0045445; P:myoblast differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
552Q6PHR2    472   ULK3_HUMAN Serine/threonine-protein kinase UL...1980.00008     50.1     27     46GO:0000407; C:pre-autophagosomal structure; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; TAS:UniProtKB.::GO:0090398; P:cellular senescence; TAS:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
553Q54PK9    908   PDPKB_DICDI 3-phosphoinositide-dependent prot...1550.00008     50.4     30     46
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
554P08458    490   SPS1_YEAST Sporulation-specific protein 1 OS=...1670.00008     50.1     28     46GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005628; C:prospore membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
555P51954    1203   NEK1_MOUSE Serine/threonine-protein kinase Ne...1590.00008     50.4     29     48GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
556Q08732    759   HRK1_YEAST Serine/threonine-protein kinase HR...1650.00008     50.1     25     45GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD.
GO:0006873; P:cellular ion homeostasis; IMP:SGD.
557Q8VCR8    613   MYLK2_MOUSE Myosin light chain kinase 2, skel...1570.00008     50.1     22     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0055007; P:cardiac muscle cell differentiation; IEP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0014816; P:satellite cell differentiation; IMP:UniProtKB.::GO:0035914; P:skeletal muscle cell differentiation; IEP:UniProtKB.
558Q9HCP0    422   KC1G1_HUMAN Casein kinase I isoform gamma-1 O...530.00008     49.7     34     72GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
559Q16659    721   MK06_HUMAN Mitogen-activated protein kinase 6...1780.00008     50.1     27     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
560O44514    474   PMK3_CAEEL Mitogen-activated protein kinase p...1690.00008     49.7     25     49GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IGI:WormBase.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.
561P23437    297   CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenop...1570.00009     49.3     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
562Q9BXA6    273   TSSK6_HUMAN Testis-specific serine/threonine-...1670.00009     48.9     26     49
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035092; P:sperm chromatin condensation; ISS:UniProtKB.
563Q5R7U1    721   MK06_PONAB Mitogen-activated protein kinase 6...1780.00009     50.1     27     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
564Q61532    720   MK06_MOUSE Mitogen-activated protein kinase 6...1780.00009     50.1     27     43GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
565Q7KRY6    599   NHK1_DROME Nucleosomal histone kinase 1 OS=Dr...550.00009     50.1     42     62GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035184; F:histone threonine kinase activity; IDA:FlyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007143; P:female meiosis; IMP:UniProtKB.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB.
566Q75GK4    447   CIPK7_ORYSJ CBL-interacting protein kinase 7 ...1690.00009     49.7     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
567P49187    464   MK10_RAT Mitogen-activated protein kinase 10 ...1630.00009     49.7     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.
568Q5ZIU3    526   DYRK2_CHICK Dual specificity tyrosine-phospho...1680.0001     49.7     28     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030145; F:manganese ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.
569P27704    720   MK06_RAT Mitogen-activated protein kinase 6 O...1780.0001     50.1     27     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
570P0C431    357   HOG1_GIBZE Mitogen-activated protein kinase H...1550.0001     49.3     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
571Q6CFS5    588   CBK1_YARLI Serine/threonine-protein kinase CB...1650.0001     49.7     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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