Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL171W
Length:
928
Number of sequences:
5887
Description:
YKL171W NNK1 SGDID:S000001654, Chr XI from 127475-130261, Genome Release 64-1-1, Verified ORF, "Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q5Z9J0    580   MPK12_ORYSJ Mitogen-activated protein kinase ...1670.0000000008     66.2     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006952; P:defense response; IEA:UniProtKB-KW.
32Q86AD7    392   MYLKB_DICDI Probable myosin light chain kinas...1650.0000000008     65.5     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
33Q5QNM6    511   CIPKD_ORYSJ Putative CBL-interacting protein ...1850.000000001     65.5     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
34O70405    1051   ULK1_MOUSE Serine/threonine-protein kinase UL...1810.000000001     65.9     28     47GO:0030659; C:cytoplasmic vesicle membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.::GO:0048675; P:axon extension; IMP:MGI.::GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0021933; P:radial glia guided migration of cerebellar granule cell; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0051386; P:regulation of nerve growth factor receptor signaling pathway; IMP:MGI.
35Q03497    939   STE20_YEAST Serine/threonine-protein kinase S...1640.000000001     65.9     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD.
GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
36Q01389    1478   BCK1_YEAST Serine/threonine-protein kinase BC...1780.000000002     65.9     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.::GO:0007584; P:response to nutrient; IMP:SGD.
37Q8W4J2    567   MPK16_ARATH Mitogen-activated protein kinase ...1670.000000002     65.1     29     48GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
38Q2ULU3    848   STE20_ASPOR Serine/threonine-protein kinase s...1640.000000002     65.5     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
39P38692    1080   KIC1_YEAST Serine/threonine-protein kinase KI...1660.000000002     65.5     26     48GO:0005933; C:cellular bud; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:0000902; P:cell morphogenesis; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.
40Q4R8T9    590   CDKL3_MACFA Cyclin-dependent kinase-like 3 OS...1570.000000002     65.1     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
41Q75DK7    971   STE20_ASHGO Serine/threonine-protein kinase S...1670.000000002     65.5     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
42Q54QI2    941   Y9877_DICDI Serine/threonine-protein kinase D...1630.000000002     65.5     29     50GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
43Q9SJG9    606   MPK20_ARATH Mitogen-activated protein kinase ...1680.000000002     65.1     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
44Q6C3J2    371   IPL1_YARLI Spindle assembly checkpoint kinase...1610.000000002     63.9     31     46GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
45P27638    372   SPK1_SCHPO Mitogen-activated protein kinase s...1990.000000002     63.9     28     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IGI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
46Q6CWQ4    361   IPL1_KLULA Spindle assembly checkpoint kinase...1680.000000003     63.9     33     48GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
47Q6L5D4    700   MPK9_ORYSJ Mitogen-activated protein kinase 9...1720.000000003     64.7     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
48Q9GN62    617   PAR4_CAEEL Serine/threonine-protein kinase pa...1710.000000003     64.3     29     53GO:0005938; C:cell cortex; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:WormBase.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IGI:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.
49Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...1570.000000004     63.9     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
50Q39023    370   MPK3_ARATH Mitogen-activated protein kinase 3...1580.000000004     63.2     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0000169; P:activation of MAPK activity involved in osmosensory signaling pathway; IDA:TAIR.::GO:0010120; P:camalexin biosynthetic process; IMP:TAIR.::GO:0048481; P:ovule development; IGI:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:0080136; P:priming of cellular response to stress; IMP:TAIR.::GO:2000038; P:regulation of stomatal complex development; IGI:TAIR.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR.::GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006970; P:response to osmotic stress; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0010224; P:response to UV-B; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
51P40417    426   ERKA_DROME Mitogen-activated protein kinase E...2200.000000005     63.2     28     43GO:0030054; C:cell junction; IDA:FlyBase.::GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:FlyBase.::GO:0019901; F:protein kinase binding; IPI:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase.
GO:0034334; P:adherens junction maintenance; IMP:FlyBase.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0006916; P:anti-apoptosis; NAS:FlyBase.::GO:0048149; P:behavioral response to ethanol; IMP:FlyBase.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0007369; P:gastrulation; NAS:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0046534; P:positive regulation of photoreceptor cell differentiation; IMP:FlyBase.::GO:0045467; P:R7 cell development; TAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase.::GO:0050804; P:regulation of synaptic transmission; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.
52Q9SEZ7    469   CIPKG_ARATH CBL-interacting serine/threonine-...1630.000000005     63.5     30     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
53Q8BLF2    595   CDKL3_MOUSE Cyclin-dependent kinase-like 3 OS...1570.000000005     63.5     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
54Q9BZL6    878   KPCD2_HUMAN Serine/threonine-protein kinase D...1670.000000005     63.9     29     54GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008219; P:cell death; IMP:BHF-UCL.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0061154; P:endothelial tube morphogenesis; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; ISS:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0050852; P:T cell receptor signaling pathway; IDA:BHF-UCL.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
55O80902    431   CIPKM_ARATH CBL-interacting serine/threonine-...1780.000000006     62.8     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
56Q0E459    506   MPK13_ORYSJ Mitogen-activated protein kinase ...1670.000000006     63.2     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
57A2X0M1    506   MPK13_ORYSI Mitogen-activated protein kinase ...1670.000000006     63.2     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
58Q7SY52    974   STK10_DANRE Serine/threonine-protein kinase 1...1780.000000006     63.5     29     50GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
59Q9JM01    593   CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R...1570.000000006     63.2     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
60Q54TH6    597   Y9863_DICDI Probable serine/threonine-protein...1660.000000007     63.2     28     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
61Q8BZ03    875   KPCD2_MOUSE Serine/threonine-protein kinase D...1670.000000007     63.5     29     54GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000573; P:positive regulation of DNA biosynthetic process; IDA:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050862; P:positive regulation of T cell receptor signaling pathway; IMP:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.
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