Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL171W
Length:
928
Number of sequences:
5887
Description:
YKL171W NNK1 SGDID:S000001654, Chr XI from 127475-130261, Genome Release 64-1-1, Verified ORF, "Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301P51817    358   PRKX_HUMAN cAMP-dependent protein kinase cata...1310.000006     53.1     30     51GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.::GO:0043542; P:endothelial cell migration; IMP:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; IDA:UniProtKB.::GO:0060993; P:kidney morphogenesis; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; IDA:UniProtKB.
302A1CAF0    380   MPKC_ASPCL Mitogen-activated protein kinase m...1540.000006     53.1     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
303Q03002    865   FRK1_YEAST Fatty acyl-CoA synthetase and RNA ...1750.000006     53.9     29     42GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
304Q8VDF3    370   DAPK2_MOUSE Death-associated protein kinase 2...1730.000006     53.1     24     49GO:0034423; C:autophagic vacuole lumen; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
305P48730    415   KC1D_HUMAN Casein kinase I isoform delta OS=H...1780.000006     53.5     26     50GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0051225; P:spindle assembly; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
306P35508    415   KC1D_BOVIN Casein kinase I isoform delta OS=B...1780.000006     53.5     26     50GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
307Q06486    415   KC1D_RAT Casein kinase I isoform delta OS=Rat...1780.000006     53.5     26     50GO:0005813; C:centrosome; TAS:RGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0005819; C:spindle; TAS:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0051219; F:phosphoprotein binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0000278; P:mitotic cell cycle; TAS:RGD.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
308Q9DC28    415   KC1D_MOUSE Casein kinase I isoform delta OS=M...1780.000006     53.5     26     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
309Q23915    1094   KINX_DICDI Probable serine/threonine-protein ...1770.000006     53.9     31     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
310O08605    427   MKNK1_MOUSE MAP kinase-interacting serine/thr...1570.000006     53.5     26     48
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; NAS:UniProtKB.
311Q5B4Z3    1346   SEPH_EMENI Cytokinesis protein sepH OS=194 / ...1670.000006     53.9     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
312Q9HG11    415   MPKC_EMENI Mitogen-activated protein kinase m...1550.000006     53.5     28     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
313Q54XQ2    1125   RCKA_DICDI RGS domain-containing serine/threo...1150.000006     53.9     32     53GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007189; P:activation of adenylate cyclase activity by G-protein signaling pathway; IGI:dictyBase.::GO:0007275; P:multicellular organismal development; IMP:dictyBase.::GO:0050921; P:positive regulation of chemotaxis; IMP:dictyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
314Q92519    343   TRIB2_HUMAN Tribbles homolog 2 OS=Homo sapien...420.000006     53.1     60     79GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL.
GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.::GO:0045081; P:negative regulation of interleukin-10 biosynthetic process; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; NAS:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
315Q91820    407   AURAA_XENLA Aurora kinase A-A OS=Xenopus laev...1810.000006     53.1     27     45GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
316Q5RC72    415   KC1D_PONAB Casein kinase I isoform delta OS=P...1800.000006     53.1     27     49GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
317Q8K4K3    343   TRIB2_MOUSE Tribbles homolog 2 OS=Mus musculu...420.000007     52.8     60     79GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IDA:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; IDA:BHF-UCL.
GO:0045599; P:negative regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IC:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
318Q0KL02    3102   TRIO_MOUSE Triple functional domain protein O...1530.000007     53.9     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
319Q5R669    343   TRIB2_PONAB Tribbles homolog 2 OS=Pongo abeli...420.000007     52.8     60     79GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
320Q28283    343   TRIB2_CANFA Tribbles homolog 2 OS=Canis famil...420.000007     52.8     60     79GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
321Q5GLH2    343   TRIB2_BOVIN Tribbles homolog 2 OS=Bos taurus ...420.000007     52.8     60     79GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
322Q96VK3    544   BUR1_EMENI Serine/threonine-protein kinase bu...1380.000007     53.5     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
323O14427    971   CLA4_CANAX Serine/threonine-protein kinase CL...1290.000007     53.9     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
324Q6GPL3    368   AUKBB_XENLA Aurora kinase B-B OS=Xenopus laev...1620.000007     52.8     27     46GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
325Q00534    326   CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo ...1630.000007     52.8     27     48GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0001726; C:ruffle; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.
GO:0014002; P:astrocyte development; ISS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0021542; P:dentate gyrus development; ISS:UniProtKB.::GO:0000080; P:G1 phase of mitotic cell cycle; IEP:BHF-UCL.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0021670; P:lateral ventricle development; ISS:UniProtKB.::GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.::GO:0009615; P:response to virus; IEP:UniProtKB.::GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB.
326Q3ULB5    682   PAK6_MOUSE Serine/threonine-protein kinase PA...1600.000007     53.5     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
327Q9QY01    1037   ULK2_MOUSE Serine/threonine-protein kinase UL...1790.000007     53.9     25     48GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0048675; P:axon extension; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010506; P:regulation of autophagy; IMP:UniProtKB.::GO:0042594; P:response to starvation; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
328Q39021    370   MPK1_ARATH Mitogen-activated protein kinase 1...1630.000007     52.8     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; TAS:TAIR.
329Q6TGC6    507   CBK1_PNECA Serine/threonine-protein kinase CB...1830.000007     53.1     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
330Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...1600.000008     53.5     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
331D4AE59    438   STK11_RAT Serine/threonine-protein kinase STK...1750.000008     53.1     30     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IMP:RGD.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:RGD.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0033993; P:response to lipid; IDA:RGD.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0001944; P:vasculature development; ISS:UniProtKB.
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