Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL171W
Length:
928
Number of sequences:
5887
Description:
YKL171W NNK1 SGDID:S000001654, Chr XI from 127475-130261, Genome Release 64-1-1, Verified ORF, "Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...1640.00000008     58.9     33     49GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
122P27636    974   CDC15_YEAST Cell division control protein 15 ...1910.00000008     60.1     26     47GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000910; P:cytokinesis; IMP:SGD.::GO:0007138; P:meiotic anaphase II; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.
123Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...1800.00000008     59.7     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
124Q9U9Y8    634   NLK_CAEEL Serine/threonine kinase NLK OS=Caen...1690.00000008     59.7     28     48GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001714; P:endodermal cell fate specification; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042694; P:muscle cell fate specification; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:WormBase.
125Q7Z8E9    914   STE20_MAGO7 Serine/threonine-protein kinase M...1590.00000009     60.1     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
126Q86YV6    388   MYLK4_HUMAN Myosin light chain kinase family ...1550.00000009     58.9     25     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
127Q4P5N0    746   STE20_USTMA Serine/threonine-protein kinase S...1660.00000009     59.7     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
128O55098    966   STK10_MOUSE Serine/threonine-protein kinase 1...1780.0000001     59.7     27     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
129P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...1700.0000001     59.3     28     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
130P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...1700.0000001     59.3     28     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
131Q922R0    355   PRKX_MOUSE cAMP-dependent protein kinase cata...1290.0000001     58.5     30     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.
GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; ISS:UniProtKB.::GO:0043542; P:endothelial cell migration; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; ISS:UniProtKB.
132Q54VI1    712   FHKE_DICDI Probable serine/threonine-protein ...1610.0000001     59.7     26     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
133Q2QMI0    454   CIPK4_ORYSJ CBL-interacting protein kinase 4 ...1660.0000001     58.9     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
134O45818    1070   DKF2_CAEEL Serine/threonine-protein kinase dk...1680.0000001     59.7     28     50GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0045089; P:positive regulation of innate immune response; IMP:WormBase.
135Q9QUK0    568   CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS...1570.0000001     59.3     26     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
136Q84UI5    398   MPK1_ORYSJ Mitogen-activated protein kinase 1...1610.0000001     58.9     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
137Q42438    533   CDPK8_ARATH Calcium-dependent protein kinase ...2030.0000001     58.9     29     47GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
138P53670    638   LIMK2_RAT LIM domain kinase 2 OS=Rattus norve...1560.0000001     58.9     29     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007286; P:spermatid development; TAS:RGD.
139Q15139    912   KPCD1_HUMAN Serine/threonine-protein kinase D...1670.0000001     59.3     29     52GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IMP:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0045806; P:negative regulation of endocytosis; TAS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:BHF-UCL.::GO:2001044; P:regulation of integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
140Q8GVC7    399   PKZ1_PHYIN Serine/threonine-protein kinase PK...1400.0000002     58.5     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
141Q99759    626   M3K3_HUMAN Mitogen-activated protein kinase k...1630.0000002     58.9     29     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.
142D0N4E2    399   PKZ1_PHYIT Serine/threonine-protein kinase PK...1400.0000002     58.2     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
143B7ZR30    950   STK10_XENLA Serine/threonine-protein kinase 1...1810.0000002     58.9     28     49GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
144Q9C9U4    576   MPK15_ARATH Mitogen-activated protein kinase ...1670.0000002     58.5     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
145Q01919    800   KIN4_YEAST Serine/threonine-protein kinase KI...1700.0000002     58.9     29     44GO:0005938; C:cell cortex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:SGD.
GO:0031578; P:mitotic cell cycle spindle orientation checkpoint; IMP:SGD.
146Q61083    619   M3K2_MOUSE Mitogen-activated protein kinase k...1630.0000002     58.5     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
147O22971    502   CIPKD_ARATH CBL-interacting serine/threonine-...1610.0000002     58.5     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
148Q9WTQ1    918   KPCD1_RAT Serine/threonine-protein kinase D1 ...1670.0000002     58.5     29     52GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.
149Q32MK0    819   MYLK3_HUMAN Putative myosin light chain kinas...1690.0000002     58.5     24     47GO:0005829; C:cytosol; ISS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; ISS:BHF-UCL.
GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.::GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.::GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.::GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; ISS:BHF-UCL.::GO:0048769; P:sarcomerogenesis; ISS:BHF-UCL.
150Q5XIT0    507   CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R...1570.0000002     58.2     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
151O42781    351   MAPK2_PNECA Mitogen-activated protein kinase ...1590.0000002     57.8     28     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0000751; P:cell cycle arrest in response to pheromone; NAS:UniProtKB.
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