Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL166C
Length:
398
Number of sequences:
5887
Description:
YKL166C TPK3 SGDID:S000001649, Chr XI from 135705-134509, Genome Release 64-1-1, reverse complement, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P54644    444   KRAC_DICDI RAC family serine/threonine-protei...2994e-85     272     45     63GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase.
32Q6GPN6    434   SGK1A_XENLA Serine/threonine-protein kinase S...2933e-84     270     45     67GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
33Q6U1I9    432   SGK1_CHICK Serine/threonine-protein kinase Sg...2933e-83     267     45     66GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
34P23443    525   KS6B1_HUMAN Ribosomal protein S6 kinase beta-...2945e-83     269     44     64GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0031929; P:TOR signaling cascade; IDA:UniProtKB.
35P67999    525   KS6B1_RAT Ribosomal protein S6 kinase beta-1 ...2945e-83     269     44     64GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004711; F:ribosomal protein S6 kinase activity; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0007616; P:long-term memory; IEP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048633; P:positive regulation of skeletal muscle tissue growth; IMP:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0046324; P:regulation of glucose import; IMP:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:UniProtKB.::GO:0043201; P:response to leucine; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0034612; P:response to tumor necrosis factor; IMP:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD.::GO:0014732; P:skeletal muscle atrophy; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD.
36P67998    525   KS6B1_RABIT Ribosomal protein S6 kinase beta-...2945e-83     269     44     64GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
37Q6TJY3    527   KS6B1_BOVIN Ribosomal protein S6 kinase beta-...2948e-83     269     44     64GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
38Q8BSK8    525   KS6B1_MOUSE Ribosomal protein S6 kinase beta-...2948e-83     269     44     64GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
39Q9P7J8    569   GAD8_SCHPO Serine/threonine-protein kinase ga...3051e-82     270     44     65
GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0031142; P:induction of conjugation upon nitrogen starvation; IGI:PomBase.::GO:2000750; P:negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; TAS:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
40Q6GLY8    434   SGK1B_XENLA Serine/threonine-protein kinase S...2931e-82     265     45     66GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
41Q7ZTW4    433   SGK1_DANRE Serine/threonine-protein kinase Sg...2932e-82     265     46     66GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
42A7MB74    431   SGK1_BOVIN Serine/threonine-protein kinase Sg...2934e-82     264     45     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
43Q5Q0U5    431   SGK1_FUNHE Serine/threonine-protein kinase Sg...2935e-82     264     45     66GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
44Q9UBS0    482   KS6B2_HUMAN Ribosomal protein S6 kinase beta-...2947e-82     265     44     63GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0006412; P:translation; TAS:ProtInc.
45Q9XT18    431   SGK1_RABIT Serine/threonine-protein kinase Sg...2931e-81     263     45     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
46P23298    683   KPCL_MOUSE Protein kinase C eta type OS=Mus m...3022e-81     269     44     64GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
47O43930    277   PRKY_HUMAN Serine/threonine-protein kinase PR...2213e-81     257     51     74
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
48Q9WVC6    431   SGK1_MOUSE Serine/threonine-protein kinase Sg...2933e-81     262     45     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.
49O00141    431   SGK1_HUMAN Serine/threonine-protein kinase Sg...2934e-81     262     45     65GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.::GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.::GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; TAS:UniProtKB.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0008217; P:regulation of blood pressure; TAS:UniProtKB.::GO:0050790; P:regulation of catalytic activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0060453; P:regulation of gastric acid secretion; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0070294; P:renal sodium ion absorption; TAS:UniProtKB.::GO:0006950; P:response to stress; TAS:ProtInc.
50Q7ZX15    486   AKT2A_XENLA RAC-beta serine/threonine-protein...3054e-81     263     42     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
51P12688    680   YPK1_YEAST Serine/threonine-protein kinase YP...3015e-81     268     45     64GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0061093; P:negative regulation of phospholipid translocation; IMP:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
52Q64617    683   KPCL_RAT Protein kinase C eta type OS=Rattus ...3025e-81     268     44     64GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070528; P:protein kinase C signaling cascade; IMP:RGD.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
53Q9QZS5    367   SGK2_MOUSE Serine/threonine-protein kinase Sg...2936e-81     259     43     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
54Q8R4U9    367   SGK2_RAT Serine/threonine-protein kinase Sgk2...2936e-81     259     43     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
55P18961    677   YPK2_YEAST Serine/threonine-protein kinase YP...3547e-81     268     40     60GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
56Q4R633    431   SGK1_MACFA Serine/threonine-protein kinase Sg...2939e-81     261     45     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
57Q9Z1M4    485   KS6B2_MOUSE Ribosomal protein S6 kinase beta-...2941e-80     262     43     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
58P24723    683   KPCL_HUMAN Protein kinase C eta type OS=Homo ...3022e-80     266     44     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
59Q8R4V0    496   SGK3_RAT Serine/threonine-protein kinase Sgk3...3054e-80     261     42     63GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007154; P:cell communication; IEA:InterPro.
60Q9HBY8    427   SGK2_HUMAN Serine/threonine-protein kinase Sg...2935e-80     258     44     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; NAS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006979; P:response to oxidative stress; TAS:ProtInc.
61P31751    481   AKT2_HUMAN RAC-beta serine/threonine-protein ...3066e-80     260     42     63GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0045444; P:fat cell differentiation; TAS:UniProtKB.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
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