Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL166C
Length:
398
Number of sequences:
5887
Description:
YKL166C TPK3 SGDID:S000001649, Chr XI from 135705-134509, Genome Release 64-1-1, reverse complement, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q6CFS5    588   CBK1_YARLI Serine/threonine-protein kinase CB...3627e-53     190     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
302Q6NW76    320   AURKB_DANRE Aurora kinase B OS=Danio rerio (Z...2898e-53     184     37     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
303Q93VD3    482   CIPKN_ARATH CBL-interacting serine/threonine-...2529e-53     188     36     59GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0010107; P:potassium ion import; IMP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR.
304P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...2629e-53     186     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
305Q10LQ2    451   CIPKA_ORYSJ CBL-interacting protein kinase 10...2869e-53     187     33     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
306Q86UX6    486   ST32C_HUMAN Serine/threonine-protein kinase 3...3101e-52     188     33     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
307Q9UQB9    309   AURKC_HUMAN Aurora kinase C OS=Homo sapiens (...2633e-52     182     36     57GO:0032133; C:chromosome passenger complex; TAS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:ProtInc.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; TAS:UniProtKB.
308Q6ZLP5    450   CIPKN_ORYSJ CBL-interacting protein kinase 23...2723e-52     186     33     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
309O14965    403   AURKA_HUMAN Aurora kinase A OS=Homo sapiens (...2623e-52     185     37     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB.
310Q8QZV4    488   ST32C_MOUSE Serine/threonine-protein kinase 3...2843e-52     187     34     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
311A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...2625e-52     184     37     56GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
312Q9Y2H9    1570   MAST1_HUMAN Microtubule-associated serine/thr...3105e-52     193     34     56GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
313Q9W1B0    1637   GEK_DROME Serine/threonine-protein kinase Gen...3551e-51     192     35     52GO:0030424; C:axon; IDA:FlyBase.::GO:0030426; C:growth cone; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0008154; P:actin polymerization or depolymerization; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0008039; P:synaptic target recognition; IMP:FlyBase.
314Q9SEZ7    469   CIPKG_ARATH CBL-interacting serine/threonine-...2711e-51     185     33     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
315O55099    343   AURKB_RAT Aurora kinase B OS=Rattus norvegicu...2722e-51     181     38     57GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:RGD.::GO:0005819; C:spindle; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007568; P:aging; IEP:RGD.::GO:0008283; P:cell proliferation; IEP:RGD.::GO:0000910; P:cytokinesis; IDA:RGD.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
316Q9NY57    414   ST32B_HUMAN Serine/threonine-protein kinase 3...2953e-51     182     33     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
317Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...2625e-51     182     37     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
318Q9JJX8    414   ST32B_MOUSE Serine/threonine-protein kinase 3...2955e-51     182     34     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
319O70126    345   AURKB_MOUSE Aurora kinase B OS=Mus musculus (...2638e-51     179     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
320Q9LWM4    461   CIPK5_ORYSJ CBL-interacting protein kinase 5 ...2668e-51     182     32     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
321Q9VA38    1105   WARTS_DROME Serine/threonine-protein kinase W...3481e-50     188     34     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IGI:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; TAS:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.
322Q2QY53    438   CIPKW_ORYSJ CBL-interacting protein kinase 32...2461e-50     181     35     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
323P54265    631   DMPK_MOUSE Myotonin-protein kinase OS=Mus mus...3051e-50     185     36     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017020; F:myosin phosphatase regulator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.::GO:0010657; P:muscle cell apoptotic process; ISS:UniProtKB.::GO:0006998; P:nuclear envelope organization; IMP:UniProtKB.::GO:0014853; P:regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction; IMP:MGI.::GO:0008016; P:regulation of heart contraction; IDA:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; IMP:UniProtKB.::GO:0014722; P:regulation of skeletal muscle contraction by calcium ion signaling; IMP:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; IMP:MGI.::GO:0051823; P:regulation of synapse structural plasticity; IMP:UniProtKB.
324Q12701    592   KSG1_SCHPO Serine/threonine-protein kinase ks...2852e-50     184     36     55GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
325P43250    576   GRK6_HUMAN G protein-coupled receptor kinase ...2852e-50     184     38     56GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
326O70293    576   GRK6_MOUSE G protein-coupled receptor kinase ...2852e-50     183     38     57GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
327Q5JLQ9    476   CIPKU_ORYSJ CBL-interacting protein kinase 30...2672e-50     181     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
328P38991    367   IPL1_YEAST Spindle assembly checkpoint kinase...3222e-50     179     35     56GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD.
329Q2RAX3    454   CIPKX_ORYSJ CBL-interacting protein kinase 33...2463e-50     181     35     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
330O14578    2027   CTRO_HUMAN Citron Rho-interacting kinase OS=H...3063e-50     188     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0033205; P:cell cycle cytokinesis; IMP:UniProtKB.::GO:0048699; P:generation of neurons; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; ISS:UniProtKB.
331Q9FJ54    439   CIPKK_ARATH CBL-interacting serine/threonine-...2944e-50     180     32     55GO:0005829; C:cytosol; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:TAIR.
GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
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