Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL165C
Length:
919
Number of sequences:
5887
Description:
YKL165C MCD4 SGDID:S000001648, Chr XI from 140691-137932, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O13663    918   GPI13_SCHPO GPI ethanolamine phosphate transf...2570.00006     50.8     24     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0051377; F:mannose-ethanolamine phosphotransferase activity; ISS:PomBase.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0006506; P:GPI anchor biosynthetic process; ISS:PomBase.
32Q74ZS2    1013   GPI13_ASHGO GPI ethanolamine phosphate transf...970.0004     48.1     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW.
33Q5EZ72    439   ENPP7_RAT Ectonucleotide pyrophosphatase/phos...780.002     45.4     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:EC.
34Q5RAC0    452   ENPP4_PONAB Ectonucleotide pyrophosphatase/ph...2720.005     43.9     24     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
35Q9Y6X5    453   ENPP4_HUMAN Ectonucleotide pyrophosphatase/ph...2690.046     40.8     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
36Q6UWV6    458   ENPP7_HUMAN Ectonucleotide pyrophosphatase/ph...770.071     40.4     25     52GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005902; C:microvillus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0004767; F:sphingomyelin phosphodiesterase activity; IDA:UniProtKB.
GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0008156; P:negative regulation of DNA replication; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006684; P:sphingomyelin metabolic process; IDA:UniProtKB.
37Q8BTJ4    456   ENPP4_MOUSE Ectonucleotide pyrophosphatase/ph...2510.088     40     24     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
38Q72XY4    509   GPMI_BACC1 2,3-bisphosphoglycerate-independen...1450.13     39.7     30     37GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
39Q6HBF2    509   GPMI_BACHK 2,3-bisphosphoglycerate-independen...1470.16     39.3     29     36GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
40Q631M1    509   GPMI_BACCZ 2,3-bisphosphoglycerate-independen...1470.16     39.3     29     36GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
41Q815K7    509   GPMI_BACCR 2,3-bisphosphoglycerate-independen...1470.16     39.3     29     36GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
42Q81X77    509   GPMI_BACAN 2,3-bisphosphoglycerate-independen...1470.16     39.3     29     36GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
43P06802    906   ENPP1_MOUSE Ectonucleotide pyrophosphatase/ph...2550.35     38.5     23     41GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.
GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0046849; P:bone remodeling; IMP:MGI.::GO:0006955; P:immune response; IEA:InterPro.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0030279; P:negative regulation of ossification; IMP:MGI.
44A0RKS4    509   GPMI_BACAH 2,3-bisphosphoglycerate-independen...1470.38     38.1     29     36GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
45O94323    485   YGK5_SCHPO Uncharacterized pyrophosphatase/ph...2530.38     38.1     21     35GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047429; F:nucleoside-triphosphate diphosphatase activity; ISS:PomBase.::GO:0004551; F:nucleotide diphosphatase activity; ISS:PomBase.
GO:0009141; P:nucleoside triphosphate metabolic process; ISS:PomBase.
46Q924C3    906   ENPP1_RAT Ectonucleotide pyrophosphatase/phos...590.96     37     31     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.
GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0006955; P:immune response; IEA:InterPro.
47A8MFH2    390   DEOB_ALKOO Phosphopentomutase OS=(strain OhIL...941.6     35.8     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008973; F:phosphopentomutase activity; IEA:EC.
GO:0043094; P:cellular metabolic compound salvage; IEA:InterPro.::GO:0009117; P:nucleotide metabolic process; IEA:InterPro.
48A7GUR8    509   GPMI_BACCN 2,3-bisphosphoglycerate-independen...1471.9     35.8     29     35GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004619; F:phosphoglycerate mutase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
49O69787    512   BETC_RHIME Choline-sulfatase OS=meliloti). GN...983.3     35     27     44
GO:0047753; F:choline-sulfatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
50Q6PGB8    1046   SMCA1_MOUSE Probable global transcription act...963.8     35     31     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0031491; F:nucleosome binding; IEA:InterPro.
GO:0043044; P:ATP-dependent chromatin remodeling; IEA:InterPro.::GO:0007420; P:brain development; ISS:HGNC.::GO:0030182; P:neuron differentiation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:HGNC.::GO:0006351; P:transcription, DNA-dependent; ISS:HGNC.
51Q6DDP3    441   ENPP6_XENLA Ectonucleotide pyrophosphatase/ph...2425.1     34.3     19     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
52O75473    907   LGR5_HUMAN Leucine-rich repeat-containing G-p...1045.3     34.7     30     45GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
53P0C6U6    4060   R1A_CVHNL Replicase polyprotein 1a OS=Human c...666.3     34.3     29     47GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
54Q6RSS2    2210   L_PIRVV RNA-directed RNA polymerase L OS=Piri...467.7     34.3     39     72GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
GO:0032774; P:RNA biosynthetic process; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.
55A2VDP5    453   ENPP4_BOVIN Ectonucleotide pyrophosphatase/ph...2648.1     33.9     22     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
56P0C6X5    6729   R1AB_CVHNL Replicase polyprotein 1ab OS=Human...668.2     34.3     29     47GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
57P22413    925   ENPP1_HUMAN Ectonucleotide pyrophosphatase/ph...1888.3     33.9     20     42GO:0016323; C:basolateral plasma membrane; NAS:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; TAS:ProtInc.
GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; IC:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:BHF-UCL.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.
GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; IDA:BHF-UCL.::GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0030643; P:cellular phosphate ion homeostasis; IDA:BHF-UCL.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0006091; P:generation of precursor metabolites and energy; IDA:BHF-UCL.::GO:0006955; P:immune response; IEA:InterPro.::GO:0030505; P:inorganic diphosphate transport; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0045599; P:negative regulation of fat cell differentiation; IDA:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IDA:BHF-UCL.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0031953; P:negative regulation of protein autophosphorylation; IDA:BHF-UCL.::GO:0009143; P:nucleoside triphosphate catabolic process; IDA:BHF-UCL.::GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IC:BHF-UCL.::GO:0006771; P:riboflavin metabolic process; TAS:Reactome.::GO:0030730; P:sequestering of triglyceride; IDA:BHF-UCL.
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