Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL140W
Length:
548
Number of sequences:
5887
Description:
YKL140W TGL1 SGDID:S000001623, Chr XI from 180779-182425, Genome Release 64-1-1, Verified ORF, "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P34163    548   TGL1_YEAST Sterol esterase TGL1 OS=Saccharomy...5480     1131     100     100GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.
GO:0004771; F:sterol esterase activity; IDA:SGD.
GO:0044255; P:cellular lipid metabolic process; IMP:SGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
2O74430    467   TGCE1_SCHPO Probable lipase C1672.09 OS=Schiz...3643e-113     351     50     63GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016298; F:lipase activity; ISS:PomBase.::GO:0004771; F:sterol esterase activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
3P78898    443   TGCE2_SCHPO Probable lipase C16A3.12c OS=Schi...4157e-110     342     43     63GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016298; F:lipase activity; ISS:PomBase.::GO:0004771; F:sterol esterase activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
4O60095    460   TGCE3_SCHPO Probable lipase C14C8.15 OS=Schiz...4164e-88     286     38     56GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016298; F:lipase activity; ISS:PomBase.::GO:0004771; F:sterol esterase activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
5P80035    398   LIPG_CANFA Gastric triacylglycerol lipase OS=...3667e-50     182     33     52GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
6Q4R4S5    399   LICH_MACFA Lysosomal acid lipase/cholesteryl ...3794e-49     180     34     51GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004771; F:sterol esterase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
7Q9Z0M5    397   LICH_MOUSE Lysosomal acid lipase/cholesteryl ...3492e-48     178     35     52GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004771; F:sterol esterase activity; IEA:EC.
GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0001816; P:cytokine production; IMP:MGI.::GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0030324; P:lung development; IMP:MGI.::GO:0048771; P:tissue remodeling; IMP:MGI.
8P38571    399   LICH_HUMAN Lysosomal acid lipase/cholesteryl ...3792e-48     177     33     51GO:0005764; C:lysosome; TAS:ProtInc.
GO:0016298; F:lipase activity; IDA:UniProtKB.::GO:0004771; F:sterol esterase activity; IDA:UniProtKB.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
9Q8BM14    398   LIPK_MOUSE Lipase member K OS=Mus musculus (M...3783e-47     175     32     51GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
10Q64194    397   LICH_RAT Lysosomal acid lipase/cholesteryl es...3727e-46     171     33     51GO:0005764; C:lysosome; IDA:RGD.
GO:0016298; F:lipase activity; IDA:RGD.::GO:0004771; F:sterol esterase activity; IDA:RGD.
GO:0006631; P:fatty acid metabolic process; IDA:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IDA:RGD.
11P04634    395   LIPG_RAT Gastric triacylglycerol lipase OS=Ra...3803e-45     169     34     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0016615; F:malate dehydrogenase activity; IDA:MGI.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC.
GO:0007586; P:digestion; TAS:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IDA:MGI.
12P07098    398   LIPG_HUMAN Gastric triacylglycerol lipase OS=...3644e-45     169     32     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; NAS:UniProtKB.::GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; TAS:UniProtKB.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006641; P:triglyceride metabolic process; NAS:UniProtKB.
13Q29458    397   LIPG_BOVIN Gastric triacylglycerol lipase OS=...3801e-43     164     33     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
14Q5VXJ0    399   LIPK_HUMAN Lipase member K OS=Homo sapiens (H...3736e-43     162     31     51GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
15Q9CPP7    395   LIPG_MOUSE Gastric triacylglycerol lipase OS=...3644e-42     160     30     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
16Q8K2A6    422   LIPM_MOUSE Lipase member M OS=Mus musculus (M...3582e-40     155     33     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
17Q5W064    366   LIPJ_HUMAN Lipase member J OS=Homo sapiens (H...3683e-40     154     30     50
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
18Q5VYY2    423   LIPM_HUMAN Lipase member M OS=Homo sapiens (H...3695e-40     154     31     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
19O46108    394   LIP3_DROME Lipase 3 OS=Drosophila melanogaste...3702e-37     147     31     46
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
20Q3U4B4    400   LIPN_MOUSE Lipase member N OS=Mus musculus (M...3626e-33     133     30     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
21Q5VXI9    398   LIPN_HUMAN Lipase member N OS=Homo sapiens (H...3623e-32     131     30     51GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
22O46107    439   LIP1_DROME Lipase 1 OS=Drosophila melanogaste...3743e-30     126     29     44GO:0005576; C:extracellular region; NAS:UniProtKB.
GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0007586; P:digestion; IEP:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
23Q71DJ5    393   LIP1_ARATH Triacylglycerol lipase 1 OS=Arabid...3812e-29     123     26     45GO:0005615; C:extracellular space; TAS:TAIR.
GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IDA:TAIR.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
24Q67ZU1    418   LIP2_ARATH Triacylglycerol lipase 2 OS=Arabid...3791e-26     115     26     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0050253; F:retinyl-palmitate esterase activity; IEA:EC.::GO:0004806; F:triglyceride lipase activity; IEA:EC.
GO:0002213; P:defense response to insect; IMP:TAIR.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
25Q07950    538   YEH2_YEAST Sterol esterase 2 OS=Saccharomyces...3939e-19     93.2     25     44GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0004771; F:sterol esterase activity; IDA:SGD.
GO:0000032; P:cell wall mannoprotein biosynthetic process; IMP:SGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
26Q07804    573   YEH1_YEAST Sterol esterase 1 OS=Saccharomyces...3570.00000000000001     80.1     25     43GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.
GO:0004771; F:sterol esterase activity; IDA:SGD.
GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0016125; P:sterol metabolic process; IMP:SGD.
records
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