Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL139W
Length:
528
Number of sequences:
5887
Description:
YKL139W CTK1 SGDID:S000001622, Chr XI from 182958-184544, Genome Release 64-1-1, Verified ORF, "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P23573    314   CDC2C_DROME Cell division control protein 2 c...2902e-66     223     41     61GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:FlyBase.::GO:0007259; P:JAK-STAT cascade; IPI:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
62Q9ZVM9    572   Y1461_ARATH Probable serine/threonine-protein...3533e-66     230     38     56GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
63P48963    298   CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesoc...3013e-66     223     39     58GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
64Q6BV06    608   BUR1_DEBHA Serine/threonine-protein kinase BU...3954e-66     231     37     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
65P43063    317   CDK1_CANAL Cyclin-dependent kinase 1 OS=Candi...2945e-66     223     41     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:CGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:CGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IGI:CGD.
66Q5E9Y0    298   CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos t...3015e-66     222     39     58GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:AgBase.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:AgBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:AgBase.::GO:0006813; P:potassium ion transport; ISS:AgBase.
67Q63699    298   CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus ...3015e-66     222     39     58GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IDA:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
68P24941    298   CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo ...3017e-66     221     39     58GO:0015030; C:Cajal body; IDA:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071732; P:cellular response to nitric oxide; TAS:UniProtKB.::GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.::GO:0016572; P:histone phosphorylation; IDA:GOC.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.::GO:0006275; P:regulation of DNA replication; TAS:ProtInc.::GO:0060968; P:regulation of gene silencing; IDA:UniProtKB.::GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
69P23111    294   CDC2_MAIZE Cell division control protein 2 ho...2948e-66     221     39     61
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007067; P:mitosis; IEA:UniProtKB-KW.
70Q6C842    706   BUR1_YARLI Serine/threonine-protein kinase BU...3411e-65     231     38     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
71Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...3071e-65     223     39     61GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
72P29618    294   CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Or...2894e-65     219     38     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
73Q00536    496   CDK16_HUMAN Cyclin-dependent kinase 16 OS=Hom...2907e-65     224     41     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
74Q09437    719   YP62_CAEEL Putative serine/threonine-protein ...3018e-65     229     42     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.
75Q00646    323   CDK1_EMENI Cyclin-dependent kinase 1 OS=194 /...3119e-65     219     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
76P52389    294   CDC2_VIGUN Cell division control protein 2 ho...2943e-64     217     39     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
77P00546    298   CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch...2963e-64     217     41     58GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD.
78O60145    398   PPK23_SCHPO Serine/threonine-protein kinase p...2983e-64     220     39     59GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
79P51958    302   CDK1_CARAU Cyclin-dependent kinase 1 OS=Caras...2924e-64     217     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
80Q04735    496   CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus...2904e-64     223     41     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
81Q07785    288   CDC2H_PLAFK Cell division control protein 2 h...2974e-64     216     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
82P61075    288   CDC2H_PLAF7 Cell division control protein 2 h...2974e-64     216     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
83A8XA58    326   CDK1_CAEBR Cyclin-dependent kinase 1 OS=Caeno...2924e-64     218     37     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051446; P:positive regulation of meiotic cell cycle; ISS:UniProtKB.
84Q80YP0    303   CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus m...2905e-64     217     40     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
85P24100    294   CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Ar...2955e-64     216     39     60GO:0010005; C:cortical microtubule, transverse to long axis; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009574; C:preprophase band; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000910; P:cytokinesis; IMP:TAIR.::GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0008284; P:positive regulation of cell proliferation; IMP:TAIR.::GO:0040020; P:regulation of meiosis; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
86Q00537    523   CDK17_HUMAN Cyclin-dependent kinase 17 OS=Hom...3406e-64     223     36     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
87P23293    657   BUR1_YEAST Serine/threonine-protein kinase BU...3308e-64     225     37     53GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IDA:SGD.
88Q4Z6R1    288   CDC2H_PLABA Cell division control protein 2 h...2971e-63     215     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
89Q9DGA2    303   CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzi...2981e-63     216     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
90O35832    451   CKD18_RAT Cyclin-dependent kinase 18 OS=Rattu...2972e-63     219     39     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
91B0VXE8    423   CDK14_CALJA Cyclin-dependent kinase 14 OS=Cal...2942e-63     218     40     59GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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