Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL139W
Length:
528
Number of sequences:
5887
Description:
YKL139W CTK1 SGDID:S000001622, Chr XI from 182958-184544, Genome Release 64-1-1, Verified ORF, "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q9TW45    1192   PAR1_CAEEL Serine/threonine-protein kinase pa...2211e-25     115     30     52GO:0005938; C:cell cortex; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.
GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0009949; P:polarity specification of anterior/posterior axis; TAS:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
542P19139    391   CSK21_RAT Casein kinase II subunit alpha OS=R...2951e-25     112     28     50GO:0005956; C:protein kinase CK2 complex; TAS:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:RGD.::GO:0042127; P:regulation of cell proliferation; NAS:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
543Q5UNT1    545   YL673_MIMIV Putative serine/threonine-protein...2241e-25     114     37     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
544A8WYE4    1088   PAR1_CAEBR Serine/threonine-protein kinase pa...2211e-25     115     30     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
545P33674    391   CSK21_RABIT Casein kinase II subunit alpha OS...2951e-25     112     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
546P40231    332   CSK2A_SCHPO Casein kinase II subunit alpha OS...2962e-25     110     28     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005956; C:protein kinase CK2 complex; TAS:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
547P28020    392   CSK21_XENLA Casein kinase II subunit alpha OS...2952e-25     111     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
548Q00372    612   SNF1_CANGA Carbon catabolite-derepressing pro...2332e-25     113     31     51GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
549O64817    333   CSK23_ARATH Probable casein kinase II subunit...3122e-25     110     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
550P32581    645   IME2_YEAST Meiosis induction protein kinase I...2223e-25     113     32     56GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0040020; P:regulation of meiosis; IMP:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
551Q5UNT4    539   YL670_MIMIV Putative serine/threonine-protein...2163e-25     113     35     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
552Q6ERS4    456   CIPKG_ORYSJ CBL-interacting protein kinase 16...2923e-25     112     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
553P27448    753   MARK3_HUMAN MAP/microtubule affinity-regulati...2174e-25     113     29     52GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
554Q8W1D5    488   CIPKP_ARATH CBL-interacting serine/threonine-...2896e-25     111     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
555Q08467    409   CSK21_ARATH Casein kinase II subunit alpha-1 ...3078e-25     110     27     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
556Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2028e-25     113     33     56GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
557Q7RAH3    535   CDPK1_PLAYO Calcium-dependent protein kinase ...3038e-25     111     29     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
558Q9SLI2    612   NEK1_ARATH Serine/threonine-protein kinase Ne...2391e-24     111     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
559Q6YY75    534   NEK6_ORYSJ Serine/threonine-protein kinase Ne...2301e-24     111     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
560Q8CIP4    752   MARK4_MOUSE MAP/microtubule affinity-regulati...2251e-24     112     28     49GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0043005; C:neuron projection; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007399; P:nervous system development; ISS:UniProtKB.
561Q7KZI7    788   MARK2_HUMAN Serine/threonine-protein kinase M...2171e-24     112     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; IDA:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
562Q05512    776   MARK2_MOUSE Serine/threonine-protein kinase M...2171e-24     111     29     51GO:0045180; C:basal cortex; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
563Q96L34    752   MARK4_HUMAN MAP/microtubule affinity-regulati...2251e-24     111     28     49GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; NAS:UniProtKB.
GO:0001578; P:microtubule bundle formation; IEP:UniProtKB.::GO:0007399; P:nervous system development; IDA:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; NAS:UniProtKB.
564O08679    722   MARK2_RAT Serine/threonine-protein kinase MAR...2172e-24     111     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
565Q38997    535   KIN10_ARATH SNF1-related protein kinase catal...2112e-24     110     33     55GO:0000152; C:nuclear ubiquitin ligase complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0009594; P:detection of nutrient; IDA:TAIR.::GO:0003006; P:developmental process involved in reproduction; IMP:TAIR.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0010260; P:organ senescence; IMP:TAIR.::GO:0080022; P:primary root development; IMP:TAIR.::GO:0006950; P:response to stress; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR.::GO:0010050; P:vegetative phase change; IMP:TAIR.
566P50527    658   STE20_SCHPO Serine/threonine-protein kinase s...2362e-24     111     31     54GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.
567Q5RAJ5    1315   STK36_PONAB Serine/threonine-protein kinase 3...2142e-24     111     31     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.
568P28523    332   CSK2A_MAIZE Casein kinase II subunit alpha OS...2962e-24     107     28     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
569P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...3063e-24     109     28     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
570P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...3063e-24     109     28     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
571P92958    512   KIN11_ARATH SNF1-related protein kinase catal...2873e-24     109     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
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