UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL139W

Length:

528

Number of sequences:

5887

Description:

YKL139W CTK1 SGDID:S000001622, Chr XI from 182958-184544, Genome Release 64-1-1, Verified ORF, "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q27032	298	CDC2H_THEPA Cell division control protein 2 h...	308	6e-73	240	40	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
32	Q96WV9	591	CDK9_SCHPO Probable cyclin-dependent kinase 9...	346	5e-72	246	38	56	GO:0070693; C:P-TEFb-cap methyltransferase complex; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
									GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; IMP:PomBase.::GO:0006360; P:transcription from RNA polymerase I promoter; IGI:PomBase.
33	Q26671	298	CDC2H_THEAN Cell division control protein 2 h...	296	7e-72	237	40	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
34	Q6ZAG3	324	CDKC3_ORYSJ Cyclin-dependent kinase C-3 OS=Or...	307	3e-70	234	40	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
35	P24788	784	CD11B_MOUSE Cyclin-dependent kinase 11B OS=Mu...	301	4e-70	245	42	62	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
									GO:0006915; P:apoptotic process; IMP:MGI.::GO:0001824; P:blastocyst development; IMP:MGI.::GO:0007088; P:regulation of mitosis; IMP:MGI.
36	P21127	795	CD11B_HUMAN Cyclin-dependent kinase 11B OS=Ho...	300	4e-70	245	41	62	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
37	Q9TVL3	478	CDK9_CAEEL Probable cyclin-dependent kinase 9...	346	7e-70	238	37	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38	P34112	296	CDK1_DICDI Cyclin-dependent kinase 1 OS=Dicty...	298	1e-69	231	42	61	GO:0005622; C:intracellular; IDA:dictyBase.
									GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
39	P46892	436	CD11B_RAT Cyclin-dependent kinase 11B OS=Ratt...	311	2e-69	235	40	60	GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
40	Q7ZX42	376	CDK9B_XENLA Cyclin-dependent kinase 9-B OS=Xe...	317	2e-69	233	40	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41	P34117	292	CDK5_DICDI Cyclin-dependent kinase 5 homolog ...	292	2e-69	231	41	61	GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0072686; C:mitotic spindle; IDA:dictyBase.::GO:0005654; C:nucleoplasm; IDA:dictyBase.::GO:0005625; C:soluble fraction; IDA:dictyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
									GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0031157; P:regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
42	Q9UQ88	783	CD11A_HUMAN Cyclin-dependent kinase 11A OS=Ho...	300	6e-69	241	42	62	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
									GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
43	Q15131	360	CDK10_HUMAN Cyclin-dependent kinase 10 OS=Hom...	306	2e-68	230	41	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
44	Q2TBL8	361	CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos...	306	2e-68	230	41	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
45	Q41639	294	CDC2_VIGAC Cell division control protein 2 ho...	294	2e-68	228	40	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
46	P29619	292	CDKA2_ORYSJ Cyclin-dependent kinase A-2 OS=Or...	293	3e-68	228	40	61
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
47	Q871M9	545	BUR1_NEUCR Serine/threonine-protein kinase bu...	364	6e-68	234	36	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
48	P23437	297	CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenop...	299	6e-68	227	38	60
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
49	Q3UMM4	360	CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus...	309	9e-68	228	41	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
50	Q4KM47	358	CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu...	309	1e-67	228	41	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
51	Q4I5U9	473	BUR1_GIBZE Serine/threonine-protein kinase BU...	368	3e-67	230	37	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
52	Q4WTN5	580	BUR1_ASPFU Serine/threonine-protein kinase bu...	338	4e-67	233	40	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
53	Q9VPC0	952	KP58_DROME Serine/threonine-protein kinase PI...	306	5e-67	238	41	61	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
									GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
54	P24923	291	CDC21_MEDSA Cell division control protein 2 h...	291	5e-67	224	40	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
55	P43450	298	CDK2_CARAU Cyclin-dependent kinase 2 OS=Caras...	301	5e-67	224	39	58
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
56	O55076	298	CDK2_CRIGR Cyclin-dependent kinase 2 OS=Crice...	301	6e-67	224	39	58	GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
57	Q38772	294	CDC2A_ANTMA Cell division control protein 2 h...	294	8e-67	224	40	61
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
58	Q00526	305	CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo ...	300	9e-67	224	39	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0045023; P:G0 to G1 transition; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
59	P93101	294	CDC2_CHERU Cell division control protein 2 ho...	292	1e-66	224	39	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
60	Q05006	294	CDC22_MEDSA Cell division control protein 2 h...	292	2e-66	223	39	61
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
61	P23573	314	CDC2C_DROME Cell division control protein 2 c...	290	2e-66	223	41	61	GO:0005875; C:microtubule associated complex; IDA:FlyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:FlyBase.::GO:0007259; P:JAK-STAT cascade; IPI:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.

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