Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL132C
Length:
430
Number of sequences:
5887
Description:
YKL132C RMA1 SGDID:S000001615, Chr XI from 194866-193574, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36001    430   FOLC_YEAST Probable folylpolyglutamate syntha...4300     885     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
2Q12676    427   FOLD_YEAST Folylpolyglutamate synthase OS=Sac...4264e-116     353     43     63GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008841; F:dihydrofolate synthase activity; IMP:SGD.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
3Q9UTD0    417   FOLD_SCHPO Probable folylpolyglutamate syntha...4303e-41     156     30     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; ISS:PomBase.
GO:0006536; P:glutamate metabolic process; NAS:PomBase.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
4Q05865    430   FOLC_BACSU Folylpolyglutamate synthase OS=Bac...3550.000000000000001     82     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
5P15925    428   FOLC_LACCA Folylpolyglutamate synthase OS=Lac...4360.00000000000003     77.8     21     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
6E7QKX4    548   FOLE_YEASZ Folylpolyglutamate synthase OS=Sac...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
7Q08645    548   FOLE_YEAST Folylpolyglutamate synthase OS=Sac...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IDA:SGD.
GO:0006730; P:one-carbon metabolic process; IMP:SGD.
8E7KUJ4    548   FOLE_YEASL Folylpolyglutamate synthase OS=Sac...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
9C8ZGZ3    548   FOLE_YEAS8 Folylpolyglutamate synthase OS=(Ba...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
10A6ZP80    548   FOLE_YEAS7 Folylpolyglutamate synthase OS=Sac...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
11B3LJR0    548   FOLE_YEAS1 Folylpolyglutamate synthase OS=Sac...1870.000000006     61.6     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
12B5VSC3    548   FOLE_YEAS6 Folylpolyglutamate synthase OS=Sac...1870.000000007     61.2     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
13E7KIA3    548   FOLE_YEASA Folylpolyglutamate synthase OS=Sac...1870.000000007     61.2     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
14E7NMM0    548   FOLE_YEASO Folylpolyglutamate synthase OS=Sac...1870.000000008     61.2     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
15E7Q9C7    548   FOLE_YEASB Folylpolyglutamate synthase OS=Sac...1870.000000008     61.2     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
16O74742    505   FOLE_SCHPO Probable folylpolyglutamate syntha...1800.0000005     55.5     27     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; ISS:PomBase.
GO:0006536; P:glutamate metabolic process; NAS:PomBase.::GO:0006730; P:one-carbon metabolic process; ISS:PomBase.
17A6H751    585   FOLC_BOVIN Folylpolyglutamate synthase, mitoc...2000.0000006     55.1     26     42GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
18P48760    587   FOLC_MOUSE Folylpolyglutamate synthase, mitoc...1980.00002     50.4     22     43GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
19Q8K9X3    418   FOLC_BUCAP Bifunctional protein folC OS=Buchn...1580.00003     49.7     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008841; F:dihydrofolate synthase activity; IEA:EC.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
20Q09509    510   FOLC_CAEEL Putative folylpolyglutamate syntha...1730.00003     49.7     24     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
21Q05932    587   FOLC_HUMAN Folylpolyglutamate synthase, mitoc...1920.00005     49.3     24     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; TAS:ProtInc.
GO:0046655; P:folic acid metabolic process; TAS:Reactome.::GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
22Q924L9    587   FOLC_CRIGR Folylpolyglutamate synthase, mitoc...2760.00005     49.3     21     40GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
23Q9Y893    514   FOLE_CANAX Folylpolyglutamate synthase OS=Can...2870.00009     48.1     25     40GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
24F4J2K2    625   FPGS2_ARATH Folylpolyglutamate synthase OS=Ar...1530.0002     47.4     27     48GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
25O13492    528   FOLE_NEUCR Folylpolyglutamate synthase OS=125...1540.0002     47     28     49GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
26Q54CY5    626   FOLC_DICDI Putative folylpolyglutamate syntha...2030.0002     47     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
27Q89AT2    426   FOLC_BUCBP Bifunctional protein folC OS=Buchn...1630.0007     45.4     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008841; F:dihydrofolate synthase activity; IEA:EC.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
28P57265    411   FOLC_BUCAI Bifunctional protein folC OS=(Acyr...1640.001     44.3     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008841; F:dihydrofolate synthase activity; IEA:EC.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0046656; P:folic acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
29F4K2A1    571   FPGS1_ARATH Folylpolyglutamate synthase OS=Ar...1520.002     43.9     25     44GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:EC.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
30Q8W035    492   FPGS3_ARATH Folylpolyglutamate synthase OS=Ar...1520.006     42.4     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IMP:TAIR.
GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
31P08192    422   FOLC_ECOLI Bifunctional protein folC OS=Esche...1470.021     40.4     24     44GO:0005737; C:cytoplasm; IDA:EcoliWiki.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008841; F:dihydrofolate synthase activity; IDA:EcoliWiki.::GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IDA:EcoliWiki.
GO:0009257; P:10-formyltetrahydrofolate biosynthetic process; IDA:EcoliWiki.::GO:0046656; P:folic acid biosynthetic process; IDA:EcoliWiki.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
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