Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL129C
Length:
1272
Number of sequences:
5887
Description:
YKL129C MYO3 SGDID:S000001612, Chr XI from 200167-196349, Genome Release 64-1-1, reverse complement, Verified ORF, "One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241P00522    1620   ABL_DROME Tyrosine-protein kinase Abl OS=Dros...650.3     39.3     40     52GO:0045179; C:apical cortex; IDA:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0005911; C:cell-cell junction; IDA:FlyBase.::GO:0005829; C:cytosol; IDA:FlyBase.::GO:0019897; C:extrinsic to plasma membrane; IDA:FlyBase.::GO:0005927; C:muscle tendon junction; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; TAS:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0007370; P:ventral furrow formation; IMP:FlyBase.
242Q6DCZ7    543   FBP1L_XENLA Formin-binding protein 1-like OS=...660.3     38.9     33     61GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
243Q5U2U2    303   CRKL_RAT Crk-like protein OS=Rattus norvegicu...750.3     38.5     33     47
244P42686    505   SRK1_SPOLA Tyrosine-protein kinase isoform SR...620.31     38.9     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
245P03949    1224   ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=C...700.35     38.9     34     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IGI:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0030336; P:negative regulation of cell migration; IGI:WormBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:WormBase.::GO:0060101; P:negative regulation of phagocytosis, engulfment; IGI:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase.
246Q8K012    605   FBP1L_MOUSE Formin-binding protein 1-like OS=...660.37     38.9     35     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
247Q28E95    861   SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF...1000.4     38.9     29     44GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
248P42690    506   SRK4_SPOLA Tyrosine-protein kinase isoform SR...620.42     38.5     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
249Q2HWF0    605   FBP1L_RAT Formin-binding protein 1-like OS=Ra...660.51     38.1     35     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
250P29355    228   SEM5_CAEEL Sex muscle abnormal protein 5 OS=C...660.72     37     32     56
GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.
251Q15052    776   ARHG6_HUMAN Rho guanine nucleotide exchange f...680.76     37.7     32     51GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
252Q8IVI9    506   NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ...650.84     37.4     35     43GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
253A6NI72    391   NCF1B_HUMAN Putative neutrophil cytosol facto...440.89     37.4     34     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
254P14598    390   NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom...440.94     37.4     34     57GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
255P81271    65   MYH11_PIG Myosin-11 OS=Sus scrofa (Pig). GN=M...440.95     34.7     36     61GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
256A8MVU1    366   NCF1C_HUMAN Putative neutrophil cytosol facto...440.99     37     34     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
257Q6YKA8    211   DRK_DROSI Protein E(sev)2B OS=Drosophila simu...611     36.6     30     54GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
258Q08012    211   DRK_DROME Protein enhancer of sevenless 2B OS...611     36.6     30     54GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
259P47941    303   CRKL_MOUSE Crk-like protein OS=Mus musculus (...751.1     36.6     32     47
GO:0005515; F:protein binding; IPI:MGI.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI.
260Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...831.1     37.4     31     43GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
261O42945    735   DHX15_SCHPO Probable pre-mRNA-splicing factor...911.2     37     29     49GO:0030686; C:90S preribosome; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006364; P:rRNA processing; ISS:UniProtKB.::GO:0000390; P:spliceosomal complex disassembly; ISS:PomBase.
262Q14562    1220   DHX8_HUMAN ATP-dependent RNA helicase DHX8 OS...671.2     37.4     33     57GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
263Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...681.2     37     32     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
264A2A4P0    1244   DHX8_MOUSE ATP-dependent RNA helicase DHX8 OS...671.3     37     33     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
265Q09014    390   NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus...551.4     36.6     33     55GO:0005829; C:cytosol; TAS:MGI.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI.
266Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...681.6     36.6     32     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
267Q8JH64    657   BTK_CHICK Tyrosine-protein kinase BTK OS=Gall...1581.8     36.6     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
268O88737    3942   BSN_MOUSE Protein bassoon OS=Mus musculus (Mo...942.2     36.6     31     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0044306; C:neuron projection terminus; IDA:MGI.::GO:0048786; C:presynaptic active zone; IDA:MGI.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
269Q9TU19    565   NPHP1_CANFA Nephrocystin-1 OS=Canis familiari...1452.4     36.2     26     41GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
270Q73RJ6    492   SYC_TREDE Cysteine--tRNA ligase OS=Treponema ...1392.7     35.8     29     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004817; F:cysteine-tRNA ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006423; P:cysteinyl-tRNA aminoacylation; IEA:InterPro.
271Q9XYM0    271   CRK_DROME Adapter molecule Crk OS=Drosophila ...702.7     35.4     30     50
GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase.
GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
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