Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL126W
Length:
680
Number of sequences:
5887
Description:
YKL126W YPK1 SGDID:S000001609, Chr XI from 205707-207749, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q9JLM8    756   DCLK1_MOUSE Serine/threonine-protein kinase D...2722e-30     131     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0048675; P:axon extension; IGI:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001764; P:neuron migration; IGI:MGI.
632Q9M9E9    343   SRK2C_ARATH Serine/threonine-protein kinase S...2682e-30     127     31     50GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0080167; P:response to karrikin; IEP:TAIR.
633Q91821    651   MELK_XENLA Maternal embryonic leucine zipper ...3312e-30     130     28     47GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
634P43291    363   SRK2A_ARATH Serine/threonine-protein kinase S...2682e-30     127     30     51GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
635Q54TW2    686   PDPKA_DICDI Probable serine/threonine-protein...1140.0000000000006     75.9     33     54
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
636A7SNN5    978   PLK4_NEMVE Serine/threonine-protein kinase PL...2622e-30     131     31     49GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
637Q5KQF5    451   CIPKM_ORYSJ CBL-interacting protein kinase 22...2813e-30     128     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
638Q28GW8    652   MELK_XENTR Maternal embryonic leucine zipper ...2893e-30     130     29     49GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
639Q9P0L2    795   MARK1_HUMAN Serine/threonine-protein kinase M...2233e-30     130     34     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
640Q7XIW5    443   CIPKT_ORYSJ CBL-interacting protein kinase 29...2683e-30     127     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
641Q9H0K1    926   SIK2_HUMAN Serine/threonine-protein kinase SI...2493e-30     130     31     52GO:0005794; C:Golgi apparatus; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
642Q7Y0B9    371   SAPK8_ORYSJ Serine/threonine-protein kinase S...2673e-30     126     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
643D3ZHP7    472   ULK3_RAT Serine/threonine-protein kinase ULK3...2544e-30     128     32     52GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
644Q02066    332   AAIP_WHEAT Abscisic acid-inducible protein ki...2624e-30     125     34     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
645A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2594e-30     128     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
646Q8N568    766   DCLK2_HUMAN Serine/threonine-protein kinase D...2704e-30     130     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
647Q00771    414   KCC1_EMENI Calcium/calmodulin-dependent prote...3255e-30     127     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
648P51956    506   NEK3_HUMAN Serine/threonine-protein kinase Ne...2495e-30     128     30     55GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB.
649Q0WPH8    956   NEK5_ARATH Serine/threonine-protein kinase Ne...3095e-30     130     31     50GO:0055028; C:cortical microtubule; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009913; P:epidermal cell differentiation; IMP:TAIR.::GO:0007017; P:microtubule-based process; IMP:TAIR.
650Q5Z6X0    514   CIPKP_ORYSJ CBL-interacting protein kinase 25...2555e-30     128     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
651O00444    970   PLK4_HUMAN Serine/threonine-protein kinase PL...2645e-30     130     30     48GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
652Q02723    502   RKIN1_SECCE Carbon catabolite-derepressing pr...2658e-30     127     30     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
653Q6PGN3    756   DCLK2_MOUSE Serine/threonine-protein kinase D...2708e-30     129     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
654P15735    406   PHKG2_HUMAN Phosphorylase b kinase gamma cata...3589e-30     125     30     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome.::GO:0045819; P:positive regulation of glycogen catabolic process; TAS:UniProtKB.
655Q2KJ16    406   PHKG2_BOVIN Phosphorylase b kinase gamma cata...3581e-29     125     29     45GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
656P28582    532   CDPK_DAUCA Calcium-dependent protein kinase O...2661e-29     127     30     53GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
657Q6ZEZ5    585   NEK3_ORYSJ Serine/threonine-protein kinase Ne...3031e-29     127     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
658O88866    714   HUNK_MOUSE Hormonally up-regulated neu tumor-...2431e-29     128     34     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
659O14408    382   KCC1_METAN Calcium/calmodulin-dependent prote...2471e-29     125     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
660P00518    387   PHKG1_RABIT Phosphorylase b kinase gamma cata...2781e-29     125     34     50GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
661Q12263    1142   GIN4_YEAST Serine/threonine-protein kinase GI...2812e-29     129     30     51GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.::GO:0000135; P:septin checkpoint; IMP:SGD.::GO:0000921; P:septin ring assembly; IGI:SGD.
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