Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL126W
Length:
680
Number of sequences:
5887
Description:
YKL126W YPK1 SGDID:S000001609, Chr XI from 205707-207749, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541P39009    513   DUN1_YEAST DNA damage response protein kinase...3032e-32     135     34     49GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0048478; P:replication fork protection; IGI:SGD.
542Q93VK0    278   PPCK2_ARATH Phosphoenolpyruvate carboxylase k...2622e-32     131     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0016036; P:cellular response to phosphate starvation; IEP:TAIR.::GO:0046898; P:response to cycloheximide; IDA:UniProtKB.::GO:0009416; P:response to light stimulus; IDA:UniProtKB.
543Q9SMQ4    350   SRK2F_ARATH Serine/threonine-protein kinase S...2702e-32     133     32     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
544B1WAR9    890   GWL_XENTR Serine/threonine-protein kinase gre...1302e-17     90.5     37     57GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.
545B3M6I4    770   PLK4_DROAN Serine/threonine-protein kinase PL...2632e-32     137     28     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
546Q6PHZ2    499   KCC2D_MOUSE Calcium/calmodulin-dependent prot...2712e-32     135     33     50GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0030315; C:T-tubule; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0060048; P:cardiac muscle contraction; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
547Q13557    499   KCC2D_HUMAN Calcium/calmodulin-dependent prot...2712e-32     135     33     50GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
548Q3MHJ9    542   KCC2B_BOVIN Calcium/calmodulin-dependent prot...2742e-32     135     35     50GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
549O77708    533   KCC2D_RABIT Calcium/calmodulin-dependent prot...2692e-32     135     33     50GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
550Q9BYT3    514   STK33_HUMAN Serine/threonine-protein kinase 3...2522e-32     135     32     52GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
551Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...2423e-32     136     33     57
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
552Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...2423e-32     136     33     57
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
553Q8CIP4    752   MARK4_MOUSE MAP/microtubule affinity-regulati...2463e-32     137     32     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0043005; C:neuron projection; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007399; P:nervous system development; ISS:UniProtKB.
554Q8ICR0    509   CDPK2_PLAF7 Calcium-dependent protein kinase ...2613e-32     134     31     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum.
555O64812    339   SRK2J_ARATH Serine/threonine-protein kinase S...2683e-32     132     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
556Q54QI2    941   Y9877_DICDI Serine/threonine-protein kinase D...2654e-32     137     33     52GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
557Q8VDU5    748   SNRK_MOUSE SNF-related serine/threonine-prote...2594e-32     136     34     52GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
558Q96L34    752   MARK4_HUMAN MAP/microtubule affinity-regulati...2464e-32     136     32     54GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; NAS:UniProtKB.
GO:0001578; P:microtubule bundle formation; IEP:UniProtKB.::GO:0007399; P:nervous system development; IDA:UniProtKB.::GO:0043068; P:positive regulation of programmed cell death; NAS:UniProtKB.
559B4KYX8    778   PLK4_DROMO Serine/threonine-protein kinase PL...2694e-32     136     27     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
560Q6DGS3    554   KC2D2_DANRE Calcium/calmodulin-dependent prot...2715e-32     134     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
561Q63553    746   SNRK_RAT SNF-related serine/threonine-protein...2595e-32     136     34     52GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043523; P:regulation of neuron apoptotic process; TAS:UniProtKB.
562Q2LYK3    777   PLK4_DROPS Serine/threonine-protein kinase PL...2645e-32     136     28     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
563Q5ZKI0    479   KCC2D_CHICK Calcium/calmodulin-dependent prot...2715e-32     133     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
564Q9DG02    475   KCC2D_XENLA Calcium/calmodulin-dependent prot...2715e-32     133     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
565O97143    769   PLK4_DROME Serine/threonine-protein kinase PL...2655e-32     136     28     49GO:0005814; C:centriole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase.
566Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...2805e-32     135     34     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
567B4HBU3    777   PLK4_DROPE Serine/threonine-protein kinase PL...2645e-32     136     28     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
568B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...2656e-32     136     28     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
569O15865    513   CDPK2_PLAFK Calcium-dependent protein kinase ...2616e-32     134     31     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
570P32562    705   CDC5_YEAST Cell cycle serine/threonine-protei...2936e-32     135     30     49GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000922; C:spindle pole; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:SGD.::GO:0090306; P:spindle assembly involved in meiosis; IMP:SGD.::GO:0070194; P:synaptonemal complex disassembly; IGI:SGD.
571Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...2556e-32     133     31     51GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
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