Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL126W
Length:
680
Number of sequences:
5887
Description:
YKL126W YPK1 SGDID:S000001609, Chr XI from 205707-207749, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361O22932    435   CIPKB_ARATH CBL-interacting serine/threonine-...2685e-42     162     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009268; P:response to pH; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
362Q12236    1081   PKH2_YEAST Serine/threonine-protein kinase PK...3325e-42     167     31     51GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
363Q9QYK9    343   KCC1B_MOUSE Calcium/calmodulin-dependent prot...2497e-42     159     37     55GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
364Q8W1D5    488   CIPKP_ARATH CBL-interacting serine/threonine-...2458e-42     162     36     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
365Q7YRC6    344   AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo...3031e-41     159     34     50GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
366Q03407    766   PKH1_YEAST Serine/threonine-protein kinase PK...2811e-41     165     32     54GO:0005829; C:cytosol; IDA:SGD.::GO:0032126; C:eisosome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
367Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...2541e-41     162     36     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
368Q5JLS2    540   CIPKC_ORYSJ CBL-interacting protein kinase 12...2481e-41     162     38     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
369Q93VD3    482   CIPKN_ARATH CBL-interacting serine/threonine-...2612e-41     161     34     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0010107; P:potassium ion import; IMP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR.
370Q6BVA0    412   IPL1_DEBHA Spindle assembly checkpoint kinase...2752e-41     159     35     54GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
371Q05999    578   KPK7_ARATH Serine/threonine-protein kinase At...3932e-41     162     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
372Q6ERS0    404   CIPKR_ORYSJ Putative CBL-interacting protein ...2633e-41     159     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
373P97477    395   AURKA_MOUSE Aurora kinase A OS=Mus musculus (...2733e-41     159     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
374Q10LQ2    451   CIPKA_ORYSJ CBL-interacting protein kinase 10...2593e-41     160     37     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
375Q7TNJ7    476   KCC1G_RAT Calcium/calmodulin-dependent protei...2653e-41     160     36     56GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0019722; P:calcium-mediated signaling; NAS:RGD.
376Q91VB2    477   KCC1G_MOUSE Calcium/calmodulin-dependent prot...2653e-41     160     36     56GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; IDA:MGI.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI.
377Q6P2M8    343   KCC1B_HUMAN Calcium/calmodulin-dependent prot...2493e-41     157     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
378Q14012    370   KCC1A_HUMAN Calcium/calmodulin-dependent prot...2674e-41     157     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; IMP:UniProtKB.::GO:0051149; P:positive regulation of muscle cell differentiation; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.::GO:0043393; P:regulation of protein binding; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
379Q91YS8    374   KCC1A_MOUSE Calcium/calmodulin-dependent prot...2674e-41     158     36     55GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:MGI.
380Q63450    374   KCC1A_RAT Calcium/calmodulin-dependent protei...2674e-41     158     36     55GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
381O14965    403   AURKA_HUMAN Aurora kinase A OS=Homo sapiens (...2736e-41     158     34     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB.
382A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...2687e-41     158     34     54GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
383Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...2677e-41     157     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
384Q9N0X0    344   AURKB_PIG Aurora kinase B OS=Sus scrofa (Pig)...3037e-41     156     34     50GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
385Q5JLD8    446   CIPK8_ORYSJ CBL-interacting protein kinase 8 ...2629e-41     158     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
386O65554    441   CIPK6_ARATH CBL-interacting serine/threonine-...2611e-40     158     36     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IDA:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
387Q9UQB9    309   AURKC_HUMAN Aurora kinase C OS=Homo sapiens (...2701e-40     155     35     52GO:0032133; C:chromosome passenger complex; TAS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:ProtInc.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; TAS:UniProtKB.
388Q683C9    282   AUR2_ARATH Serine/threonine-protein kinase Au...2691e-40     154     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR.
389Q0JI49    502   CIPKB_ORYSJ CBL-interacting protein kinase 11...2451e-40     159     36     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
390Q6ZLP5    450   CIPKN_ORYSJ CBL-interacting protein kinase 23...2911e-40     158     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
391P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...2672e-40     156     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
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