UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YKL121W

Length:

852

Number of sequences:

5887

Description:

YKL121W DGR2 SGDID:S000001604, Chr XI from 214142-216700, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q86VZ2	330	WDR5B_HUMAN WD repeat-containing protein 5B O...	71	0.67	37	30	54
32	Q54KL5	335	WDR5_DICDI WD repeat-containing protein 5 hom...	202	0.026	41.2	21	40	GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
									GO:0042393; F:histone binding; ISS:dictyBase.
									GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
33	P38262	535	SIF2_YEAST SIR4-interacting protein SIF2 OS=S...	215	0.0001	49.3	26	43	GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0034967; C:Set3 complex; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IMP:SGD.::GO:0045835; P:negative regulation of meiosis; IPI:SGD.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:SGD.
34	P49846	704	TAF5_DROME Transcription initiation factor TF...	229	0.0001	49.3	22	41	GO:0000124; C:SAGA complex; IPI:FlyBase.::GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
									GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:GOC.
35	Q5F3D7	520	UTP15_CHICK U3 small nucleolar RNA-associated...	295	0.0002	48.5	22	35	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
36	Q8YV57	1683	Y2124_NOSS1 Uncharacterized WD repeat-contain...	222	0.18	39.3	21	41
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:InterPro.
37	Q6GPP0	622	WDR70_XENLA WD repeat-containing protein 70 O...	56	0.0003	48.1	34	57
38	Q9VZF4	1326	FBXW7_DROME F-box/WD repeat-containing protei...	191	0.0004	48.1	23	39	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase.
									GO:0030332; F:cyclin binding; TAS:FlyBase.
									GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.
39	O75529	589	TAF5L_HUMAN TAF5-like RNA polymerase II p300/...	103	0.006	43.9	31	47	GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
									GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
40	Q8C092	801	TAF5_MOUSE Transcription initiation factor TF...	180	0.0004	47.8	24	38	GO:0005634; C:nucleus; IDA:MGI.
									GO:0003677; F:DNA binding; IDA:MGI.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41	Q8YRI1	1526	YY46_NOSS1 Uncharacterized WD repeat-containi...	223	0.61	37.7	20	33
42	Q7ZXZ2	515	UTP15_XENLA U3 small nucleolar RNA-associated...	259	0.0005	47	23	40	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
43	Q74ZN0	825	HIR1_ASHGO Protein HIR1 OS=Y-1056) (Yeast) (E...	196	0.0006	47.4	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44	Q15542	800	TAF5_HUMAN Transcription initiation factor TF...	180	0.0006	47.4	24	38	GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
									GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0016573; P:histone acetylation; IDA:GOC.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
45	Q8N136	415	WDR69_HUMAN Outer row dynein assembly protein...	71	3.1	35	27	49	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
46	A7MB12	519	UTP15_BOVIN U3 small nucleolar RNA-associated...	241	0.0007	46.6	22	35	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
47	C4YFX2	511	TUP1_CANAW Transcriptional repressor TUP1 OS=...	219	0.005	44.3	26	39
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48	P0CY34	512	TUP1_CANAL Transcriptional repressor TUP1 OS=...	219	0.005	44.3	26	39	GO:0005625; C:soluble fraction; IDA:CGD.
									GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49	Q0P593	415	WDR69_BOVIN Outer row dynein assembly protein...	271	4.3	34.3	22	35	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
50	Q229Z6	634	POC1_TETTS POC1 centriolar protein homolog OS...	231	0.001	46.6	24	40	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.
									GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0051297; P:centrosome organization; IMP:UniProtKB.
51	Q8TED0	518	UTP15_HUMAN U3 small nucleolar RNA-associated...	241	0.001	46.2	23	35	GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
52	O43017	380	SWD3_SCHPO Set1 complex component swd3 OS=Sch...	209	0.001	45.4	22	41	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase.
									GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0051568; P:histone H3-K4 methylation; IMP:PomBase.
53	Q6FVD3	840	HIR1_CANGA Protein HIR1 OS=NRRL Y-65) (Yeast)...	194	0.001	46.2	25	39	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54	P16649	713	TUP1_YEAST General transcriptional corepresso...	223	0.001	45.8	20	38	GO:0017053; C:transcriptional repressor complex; IDA:SGD.
									GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
									GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
55	Q1LV15	415	WDR69_DANRE Outer row dynein assembly protein...	127	0.15	39.3	28	46	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
									GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
56	Q6BYU4	985	HIR1_DEBHA Protein HIR1 OS=0083 / IGC 2968) (...	197	0.002	45.8	22	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003682; F:chromatin binding; IEA:InterPro.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57	Q91WQ5	589	TAF5L_MOUSE TAF5-like RNA polymerase II p300/...	103	0.003	44.7	31	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58	Q5XGE2	515	UTP15_XENTR U3 small nucleolar RNA-associated...	256	0.002	45.1	23	41	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
59	Q4R8E7	415	WDR69_MACFA Outer row dynein assembly protein...	71	3	35	27	48	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
60	Q0VA16	622	WDR70_XENTR WD repeat-containing protein 70 O...	56	0.003	45.1	34	55
61	P78972	488	SLP1_SCHPO WD repeat-containing protein slp1 ...	203	0.003	44.7	20	38	GO:0032153; C:cell division site; IDA:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IGI:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IGI:PomBase.

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