Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL121W
Length:
852
Number of sequences:
5887
Description:
YKL121W DGR2 SGDID:S000001604, Chr XI from 214142-216700, Genome Release 64-1-1, Uncharacterized ORF, "Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...794.1     34.3     28     48GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
152Q12788    808   TBL3_HUMAN Transducin beta-like protein 3 OS=...1910.071     40.4     23     42GO:0005730; C:nucleolus; IDA:HPA.::GO:0032040; C:small-subunit processome; IEA:InterPro.
GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
GO:0007199; P:G-protein signaling, coupled to cGMP nucleotide second messenger; TAS:ProtInc.::GO:0006364; P:rRNA processing; IEA:InterPro.
153Q9NDC9    404   LIS1_CAEEL Lissencephaly-1 homolog OS=Caenorh...590.071     40     29     51GO:0005818; C:aster; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IDA:WormBase.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:WormBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051026; P:chiasma assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0043652; P:engulfment of apoptotic cell; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007018; P:microtubule-based movement; IMP:WormBase.::GO:0007100; P:mitotic centrosome separation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0051225; P:spindle assembly; IMP:WormBase.::GO:0051932; P:synaptic transmission, GABAergic; IMP:WormBase.::GO:0048489; P:synaptic vesicle transport; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
154Q6CXX3    861   HIR1_KLULA Protein HIR1 OS=1267 / NRRL Y-1140...1800.074     40.4     20     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
155O16519    620   GAD1_CAEEL Gastrulation defective protein 1 O...240.078     40.4     58     71
GO:0005515; F:protein binding; IPI:IntAct.
GO:0042074; P:cell migration involved in gastrulation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:WormBase.
156Q9UTC7    462   YIDC_SCHPO Uncharacterized WD repeat-containi...820.079     40     35     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
157Q9XF57    317   PEX7_ARATH Peroxisome biogenesis protein 7 OS...840.08     39.7     31     50GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005053; F:peroxisome matrix targeting signal-2 binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
158Q01369    316   GBLP_NEUCR Guanine nucleotide-binding protein...790.08     39.7     34     51
159Q5ZIU8    657   KTNB1_CHICK Katanin p80 WD40-containing subun...1780.082     40     21     38GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
160Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...2110.092     39.7     23     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
161Q8BX17    1502   GEMI5_MOUSE Gem-associated protein 5 OS=Mus m...1770.53     37.7     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0017069; F:snRNA binding; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
162P83774    317   GBLP_CANAL Guanine nucleotide-binding protein...1064.2     34.3     22     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:CGD.
GO:0007155; P:cell adhesion; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.
163Q7ZVF0    416   POC1A_DANRE POC1 centriolar protein homolog A...1790.098     39.7     21     39
164Q5M786    334   WDR5_XENTR WD repeat-containing protein 5 OS=...2510.93     36.6     20     37GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
165Q6NLV4    647   FY_ARATH Flowering time control protein FY OS...1960.098     40     24     39GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IGI:TAIR.::GO:0009909; P:regulation of flower development; IMP:TAIR.
166Q759L2    346   EIF3I_ASHGO Eukaryotic translation initiation...1010.099     39.7     21     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
167A0JPH4    1311   SCAP_XENLA Sterol regulatory element-binding ...2220.1     40     24     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
168A1DP19    441   LIS1_NEOFI Nuclear distribution protein nudF ...940.1     39.7     28     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
169O43071    558   PRP17_SCHPO Pre-mRNA-processing factor 17 OS=...1050.11     39.7     28     47GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
170Q95RJ9    700   EBI_DROME F-box-like/WD repeat-containing pro...950.11     40     26     42GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0017053; C:transcriptional repressor complex; IGI:FlyBase.
GO:0003682; F:chromatin binding; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IPI:GOC.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0042461; P:photoreceptor cell development; IMP:FlyBase.::GO:0031065; P:positive regulation of histone deacetylation; IDA:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
171Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...2600.11     40     20     40GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
172Q5ZME8    513   SMU1_CHICK WD40 repeat-containing protein SMU...1930.56     37.4     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
173Q8BG40    658   KTNB1_MOUSE Katanin p80 WD40-containing subun...1760.11     39.7     22     37GO:0030424; C:axon; IDA:MGI.::GO:0005813; C:centrosome; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0045502; F:dynein binding; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
174P41318    303   LST8_YEAST Target of rapamycin complex subuni...2132.3     35     20     40GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD.
175Q9BVA0    655   KTNB1_HUMAN Katanin p80 WD40-containing subun...1760.12     39.7     22     37GO:0008352; C:katanin complex; TAS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0008017; F:microtubule binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0031117; P:positive regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0006605; P:protein targeting; NAS:UniProtKB.
176C3XVT5    406   LIS1_BRAFL Lissencephaly-1 homolog OS=Branchi...822.9     35     30     48GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
177Q4P9P9    453   LIS1_USTMA Nuclear distribution protein PAC1 ...1693.2     35     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
178Q6NRT3    513   SMU1_XENLA WD40 repeat-containing protein SMU...1930.41     37.7     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
179Q498M4    334   WDR5_RAT WD repeat-containing protein 5 OS=Ra...2511.8     35.4     20     37GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
180P61965    334   WDR5_MOUSE WD repeat-containing protein 5 OS=...2511.8     35.4     20     37GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
181P61964    334   WDR5_HUMAN WD repeat-containing protein 5 OS=...2511.8     35.4     20     37GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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