Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL116C
Length:
518
Number of sequences:
5887
Description:
YKL116C PRR1 SGDID:S000001599, Chr XI from 222900-221344, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751O94804    968   STK10_HUMAN Serine/threonine-protein kinase 1...2670.000000000008     71.6     24     42GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
752P38691    1029   KSP1_YEAST Serine/threonine-protein kinase KS...1720.000000000008     71.6     31     45GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0030447; P:filamentous growth; IMP:SGD.::GO:2000220; P:regulation of pseudohyphal growth; IMP:SGD.
753Q62673    603   PLK1_RAT Serine/threonine-protein kinase PLK1...1110.000000000008     71.2     32     53GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; IDA:RGD.::GO:0000922; C:spindle pole; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0000236; P:mitotic prometaphase; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:RGD.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; IEP:RGD.
754Q9Y2U5    619   M3K2_HUMAN Mitogen-activated protein kinase k...2640.000000000008     71.2     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
755O54988    1233   SLK_MOUSE STE20-like serine/threonine-protein...3470.000000000008     71.6     24     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
756Q6BVA0    412   IPL1_DEBHA Spindle assembly checkpoint kinase...2200.000000000008     70.5     28     43GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
757Q13237    762   KGP2_HUMAN cGMP-dependent protein kinase 2 OS...1410.000000000009     71.2     30     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
758Q6DFJ6    725   TBK1_XENLA Serine/threonine-protein kinase TB...2020.000000000009     71.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
759P38070    525   YPK3_YEAST AGC kinase YPK3 OS=Saccharomyces c...2820.000000000009     70.9     25     42GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
760P24719    497   MEK1_YEAST Meiosis-specific serine/threonine-...3530.000000000009     70.9     25     42GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0051598; P:meiotic recombination checkpoint; IMP:SGD.
761O94806    890   KPCD3_HUMAN Serine/threonine-protein kinase D...3030.000000000009     71.6     22     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
762O94647    461   PPK24_SCHPO Serine/threonine-protein kinase p...1940.000000000009     70.9     28     42GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase.
763Q91447    388   MP2K1_SERCA Dual specificity mitogen-activate...2070.000000000009     70.5     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
764P54737    380   PKN5_MYXXA Serine/threonine-protein kinase pk...1280.000000000009     70.5     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
765Q6PFQ0    740   KS6A6_DANRE Ribosomal protein S6 kinase alpha...1730.00000000001     71.2     31     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
766Q5U2X5    1040   ACK1_RAT Activated CDC42 kinase 1 OS=Rattus n...2460.00000000001     71.2     26     39GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
767Q9ERE3    496   SGK3_MOUSE Serine/threonine-protein kinase Sg...2610.00000000001     70.9     28     43GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0007154; P:cell communication; IEA:InterPro.
768Q38SD2    2015   LRRK1_HUMAN Leucine-rich repeat serine/threon...2580.00000000001     71.6     29     46GO:0005739; C:mitochondrion; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
769P53351    682   PLK2_MOUSE Serine/threonine-protein kinase PL...1430.00000000001     70.9     30     50GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; IMP:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
770Q683C9    282   AUR2_ARATH Serine/threonine-protein kinase Au...3220.00000000001     68.9     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR.
771Q8N5S9    505   KKCC1_HUMAN Calcium/calmodulin-dependent prot...1910.00000000001     70.5     28     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0007268; P:synaptic transmission; TAS:Reactome.
772Q556S2    513   PAKH_DICDI Serine/threonine-protein kinase pa...2750.00000000001     70.5     24     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
773P62205    598   PLK1_XENTR Serine/threonine-protein kinase PL...1980.00000000001     70.9     26     44GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
774Q622Z7    640   GRK1_CAEBR G protein-coupled receptor kinase ...3320.00000000001     70.9     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
775Q9S2C0    556   PKSC_STRCO Serine/threonine-protein kinase pk...2580.00000000001     70.5     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
776Q9ST27    907   PHOT2_ORYSJ Phototropin-2 OS=Oryza sativa sub...2780.00000000001     70.9     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
777P50530    696   SCK1_SCHPO Serine/threonine-protein kinase sc...2130.00000000001     70.9     28     42GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0019933; P:cAMP-mediated signaling; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IGI:PomBase.::GO:0090062; P:regulation of trehalose metabolic process; IMP:PomBase.
778Q9R012    682   PLK2_RAT Serine/threonine-protein kinase PLK2...1430.00000000001     70.9     30     50GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; IDA:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; IDA:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
779P16911    376   KDC1_DROME Protein kinase DC1 OS=Drosophila m...1100.00000000001     69.7     32     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
780Q10KY3    600   CAMK1_ORYSJ Calcium/calmodulin-dependent seri...1410.00000000001     70.5     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
781D2I3C6    784   DCLK2_AILME Serine/threonine-protein kinase D...2540.00000000001     70.9     28     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
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