Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL116C
Length:
518
Number of sequences:
5887
Description:
YKL116C PRR1 SGDID:S000001599, Chr XI from 222900-221344, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721Q5R7A7    496   SGK3_PONAB Serine/threonine-protein kinase Sg...2610.000000000004     72     27     43GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007154; P:cell communication; IEA:InterPro.
722Q96BR1    496   SGK3_HUMAN Serine/threonine-protein kinase Sg...2610.000000000004     72     27     43GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.::GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0030334; P:regulation of cell migration; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0006950; P:response to stress; TAS:ProtInc.
723Q02750    393   MP2K1_HUMAN Dual specificity mitogen-activate...2100.000000000004     71.6     29     45GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.::GO:0090398; P:cellular senescence; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
724P29678    393   MP2K1_RABIT Dual specificity mitogen-activate...2100.000000000004     71.6     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
725P31938    393   MP2K1_MOUSE Dual specificity mitogen-activate...2100.000000000004     71.2     29     45GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IMP:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; IMP:MGI.
GO:0048870; P:cell motility; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060711; P:labyrinthine layer development; IMP:MGI.::GO:0060674; P:placenta blood vessel development; IMP:MGI.::GO:0045597; P:positive regulation of cell differentiation; IDA:MGI.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.
726Q54WX4    384   AURK_DICDI Aurora kinase OS=Dictyostelium dis...1940.000000000004     71.2     24     43GO:0005813; C:centrosome; IDA:dictyBase.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IDA:dictyBase.::GO:0051233; C:spindle midzone; IDA:dictyBase.::GO:0000922; C:spindle pole; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000278; P:mitotic cell cycle; ISS:dictyBase.
727Q6PHR2    472   ULK3_HUMAN Serine/threonine-protein kinase UL...2050.000000000005     71.6     30     47GO:0000407; C:pre-autophagosomal structure; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; TAS:UniProtKB.::GO:0090398; P:cellular senescence; TAS:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
728Q63092    504   CAMKV_RAT CaM kinase-like vesicle-associated ...1950.000000000005     71.6     29     47GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0004672; F:protein kinase activity; IEA:InterPro.
729P50528    683   PLO1_SCHPO Serine/threonine-protein kinase pl...1610.000000000005     72     28     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; IMP:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:PomBase.
730P08413    542   KCC2B_RAT Calcium/calmodulin-dependent protei...3030.000000000005     71.6     26     44GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060291; P:long-term synaptic potentiation; IMP:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
731Q9Z2A0    559   PDPK1_MOUSE 3-phosphoinositide-dependent prot...2620.000000000005     71.6     31     44GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB.
732Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...2820.000000000005     71.6     28     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
733Q9Y6R4    1608   M3K4_HUMAN Mitogen-activated protein kinase k...3330.000000000005     72.4     21     40GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.
734P28652    542   KCC2B_MOUSE Calcium/calmodulin-dependent prot...3030.000000000005     71.6     26     44GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI.
GO:0060466; P:activation of meiosis involved in egg activation; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0031558; P:induction of apoptosis in response to chemical stimulus; IDA:MGI.::GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IDA:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0032222; P:regulation of synaptic transmission, cholinergic; IMP:MGI.::GO:0046686; P:response to cadmium ion; IDA:MGI.
735Q5VT25    1732   MRCKA_HUMAN Serine/threonine-protein kinase M...1470.000000000006     72.4     32     48GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
736Q8TFN2    804   ATG1_PICAN Serine/threonine-protein kinase AT...2830.000000000006     72     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
737Q07832    603   PLK1_MOUSE Serine/threonine-protein kinase PL...1110.000000000006     71.6     32     53GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
738Q9S9V0    484   CDPKV_ARATH Calcium-dependent protein kinase ...2760.000000000006     71.2     26     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.
739Q5B4Z3    1346   SEPH_EMENI Cytokinesis protein sepH OS=194 / ...1880.000000000007     72     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
740O55173    559   PDPK1_RAT 3-phosphoinositide-dependent protei...2610.000000000007     71.2     30     43GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.
GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
741Q07912    1038   ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo s...2460.000000000007     72     26     39GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0070436; C:Grb2-EGFR complex; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.::GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.::GO:0050699; F:WW domain binding; ISS:BHF-UCL.
GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
742Q55FJ6    507   Y8078_DICDI Probable serine/threonine-protein...2480.000000000007     71.2     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
743Q54RZ7    1634   Y1199_DICDI Probable serine/threonine-protein...1950.000000000007     72     30     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
744P53350    603   PLK1_HUMAN Serine/threonine-protein kinase PL...1110.000000000007     71.2     32     54GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000942; C:condensed nuclear chromosome outer kinetochore; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0051233; C:spindle midzone; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:BHF-UCL.
GO:0010997; F:anaphase-promoting complex binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0051297; P:centrosome organization; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.::GO:0007091; P:mitotic metaphase/anaphase transition; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0000088; P:mitotic prophase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.::GO:0031648; P:protein destabilization; IDA:UniProtKB.::GO:0071168; P:protein localization to chromatin; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0090007; P:regulation of mitotic anaphase; IMP:BHF-UCL.::GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.
745O08648    1597   M3K4_MOUSE Mitogen-activated protein kinase k...2640.000000000007     72     23     42GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
746Q90ZY4    385   SBK1_DANRE Serine/threonine-protein kinase SB...2010.000000000007     70.5     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
747Q61083    619   M3K2_MOUSE Mitogen-activated protein kinase k...2630.000000000007     71.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
748Q6XHB2    1726   ROCO4_DICDI Probable serine/threonine-protein...2560.000000000008     72     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
749Q2TA25    602   PLK1_BOVIN Serine/threonine-protein kinase PL...1110.000000000008     71.2     32     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
750P51953    344   CDK7_CARAU Cyclin-dependent kinase 7 OS=Caras...2680.000000000008     70.1     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
751O94804    968   STK10_HUMAN Serine/threonine-protein kinase 1...2670.000000000008     71.6     24     42GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
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