Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL116C
Length:
518
Number of sequences:
5887
Description:
YKL116C PRR1 SGDID:S000001599, Chr XI from 222900-221344, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q6P3R8    708   NEK5_HUMAN Serine/threonine-protein kinase Ne...1460.00000000000008     77.8     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
542Q03963    515   E2AK2_MOUSE Interferon-induced, double-strand...2510.00000000000008     77.4     27     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IDA:MGI.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:MGI.::GO:0033689; P:negative regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006412; P:translation; IDA:MGI.::GO:0006926; P:virus-infected cell apoptotic process; IDA:MGI.
543P53104    897   ATG1_YEAST Serine/threonine-protein kinase AT...2780.00000000000009     77.8     26     43GO:0034273; C:Atg1p signaling complex; IPI:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.
GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0032258; P:CVT pathway; IMP:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.
544A6ZU07    897   ATG1_YEAS7 Serine/threonine-protein kinase AT...2780.00000000000009     77.8     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
545Q6P0Q8    1798   MAST2_HUMAN Microtubule-associated serine/thr...1570.00000000000009     78.2     31     47GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045075; P:regulation of interleukin-12 biosynthetic process; ISS:UniProtKB.::GO:0048515; P:spermatid differentiation; ISS:UniProtKB.
546P10829    697   KPCG_RABIT Protein kinase C gamma type OS=Ory...1430.00000000000009     77.4     30     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
547O62305    720   KCC2D_CAEEL Calcium/calmodulin-dependent prot...2010.00000000000009     77.4     29     43GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009931; F:calcium-dependent protein serine/threonine kinase activity; IDA:WormBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:WormBase.::GO:0044325; F:ion channel binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
548B4LDJ6    781   PLK4_DROVI Serine/threonine-protein kinase PL...2190.00000000000009     77.8     27     50GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
549O14920    756   IKKB_HUMAN Inhibitor of nuclear factor kappa-...2630.0000000000001     77.8     25     42GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0008385; C:IkappaB kinase complex; TAS:UniProtKB.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0008384; F:IkappaB kinase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
550Q2LYK3    777   PLK4_DROPS Serine/threonine-protein kinase PL...2170.0000000000001     77.8     25     47GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
551B4HBU3    777   PLK4_DROPE Serine/threonine-protein kinase PL...2170.0000000000001     77.8     25     47GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
552A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...3170.0000000000001     76.6     24     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
553Q9XBQ0    547   PKN3_MYXXA Serine/threonine-protein kinase pk...2170.0000000000001     77     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
554A3B529    435   CIPKS_ORYSJ CBL-interacting protein kinase 28...2330.0000000000001     76.6     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
555Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...3170.0000000000001     76.3     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
556Q08217    1101   PSK2_YEAST Serine/threonine-protein kinase PS...1770.0000000000001     77.4     29     51GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
557Q91ZN7    476   CHK1_RAT Serine/threonine-protein kinase Chk1...2630.0000000000001     76.6     25     42GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD.
GO:0071313; P:cellular response to caffeine; IEP:RGD.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:RGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:RGD.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:RGD.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.
558P12688    680   YPK1_YEAST Serine/threonine-protein kinase YP...1420.0000000000001     77     30     53GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0061093; P:negative regulation of phospholipid translocation; IMP:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
559Q09170    460   CDS1_SCHPO Serine/threonine-protein kinase cd...2670.0000000000001     76.3     26     43GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
560Q5KQF5    451   CIPKM_ORYSJ CBL-interacting protein kinase 22...2220.0000000000001     76.3     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
561A8WXF6    533   KCC2D_CAEBR Calcium/calmodulin-dependent prot...2080.0000000000002     76.3     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
562P32023    934   KGP25_DROME cGMP-dependent protein kinase, is...1590.0000000000002     77     29     48GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.
GO:0046959; P:habituation; IMP:FlyBase.::GO:0030536; P:larval feeding behavior; IMP:UniProtKB.::GO:0008345; P:larval locomotory behavior; IMP:FlyBase.::GO:0007616; P:long-term memory; IMP:FlyBase.::GO:0008016; P:regulation of heart contraction; IMP:FlyBase.::GO:0032095; P:regulation of response to food; IMP:FlyBase.::GO:0009744; P:response to sucrose stimulus; IDA:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.
563Q7RJG2    528   CDPK4_PLAYO Calcium-dependent protein kinase ...2650.0000000000002     76.3     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
564P31374    1356   PSK1_YEAST Serine/threonine-protein kinase PS...1120.0000000000002     77     34     56GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
565P62345    528   CDPK4_PLABA Calcium-dependent protein kinase ...2650.0000000000002     76.3     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
566P50527    658   STE20_SCHPO Serine/threonine-protein kinase s...1420.0000000000002     76.6     32     48GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.
567P12370    353   KAPC_DROME cAMP-dependent protein kinase cata...2570.0000000000002     75.1     23     47GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007615; P:anesthesia-resistant memory; IMP:FlyBase.::GO:0007448; P:anterior/posterior pattern specification, imaginal disc; IMP:FlyBase.::GO:0048149; P:behavioral response to ethanol; NAS:FlyBase.::GO:0019933; P:cAMP-mediated signaling; NAS:FlyBase.::GO:0048749; P:compound eye development; NAS:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; NAS:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IGI:FlyBase.::GO:0008355; P:olfactory learning; NAS:FlyBase.::GO:0007314; P:oocyte anterior/posterior axis specification; IMP:FlyBase.::GO:0008103; P:oocyte microtubule cytoskeleton polarization; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0008359; P:regulation of bicoid mRNA localization; IMP:FlyBase.::GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IMP:FlyBase.::GO:0007317; P:regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0050804; P:regulation of synaptic transmission; IMP:FlyBase.
568P41719    267   PK1_NPVHZ Serine/threonine-protein kinase 1 O...1740.0000000000002     73.9     32     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
569A8X6H1    749   EGL4_CAEBR cGMP-dependent protein kinase egl-...1530.0000000000002     76.6     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
570P93025    915   PHOT2_ARATH Phototropin-2 OS=Arabidopsis thal...3570.0000000000002     76.6     25     39GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IMP:TAIR.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009902; P:chloroplast relocation; TAS:TAIR.::GO:0010362; P:negative regulation of anion channel activity by blue light; IMP:TAIR.::GO:0009638; P:phototropism; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; TAS:TAIR.::GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR.
571Q54WW7    695   Y0010_DICDI Probable serine/threonine-protein...2000.0000000000002     76.3     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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