Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL101W
Length:
1518
Number of sequences:
5887
Description:
YKL101W HSL1 SGDID:S000001584, Chr XI from 248920-253476, Genome Release 64-1-1, Verified ORF, "Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841P41892    1062   CDC7_SCHPO Cell division control protein 7 OS...2941e-26     122     30     48GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
842Q61036    559   PAK3_MOUSE Serine/threonine-protein kinase PA...2931e-26     120     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.
843P35465    544   PAK1_RAT Serine/threonine-protein kinase PAK ...2931e-26     119     27     50GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0030018; C:Z disc; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0033554; P:cellular response to stress; IDA:RGD.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:RGD.::GO:0042060; P:wound healing; ISS:UniProtKB.
844O60229    2985   KALRN_HUMAN Kalirin OS=Homo sapiens (Human). ...2642e-26     122     29     52GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; ISS:HGNC.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
845O75116    1388   ROCK2_HUMAN Rho-associated protein kinase 2 O...2982e-26     122     29     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005198; F:structural molecule activity; NAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051298; P:centrosome duplication; IMP:UniProtKB.::GO:0000910; P:cytokinesis; NAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.::GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
846O19111    591   KPCZ_RABIT Protein kinase C zeta type OS=Oryc...2892e-26     120     29     49GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:2001181; P:positive regulation of interleukin-10 secretion; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.::GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:UniProtKB.
847Q3SYZ2    384   MAPK3_BOVIN MAP kinase-activated protein kina...2182e-26     118     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
848Q8K4K4    372   TRIB1_MOUSE Tribbles homolog 1 OS=Mus musculu...2032e-26     118     34     56
GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IDA:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; IDA:BHF-UCL.
GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IC:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IMP:BHF-UCL.
849Q9Y7J6    550   PPK21_SCHPO Serine/threonine-protein kinase p...2982e-26     119     29     45GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0033205; P:cell cycle cytokinesis; TAS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
850Q16975    743   KPC2_APLCA Calcium-independent protein kinase...2932e-26     120     30     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
851Q96RU8    372   TRIB1_HUMAN Tribbles homolog 1 OS=Homo sapien...2032e-26     117     34     56GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0031434; F:mitogen-activated protein kinase kinase binding; IDA:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; IMP:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.::GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL.
GO:0007254; P:JNK cascade; IMP:BHF-UCL.::GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:BHF-UCL.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0043405; P:regulation of MAP kinase activity; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IMP:BHF-UCL.
852P97924    2959   KALRN_RAT Kalirin OS=Rattus norvegicus (Rat)....2642e-26     122     29     52GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007409; P:axonogenesis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:HGNC.::GO:0050773; P:regulation of dendrite development; IDA:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
853Q8RXG3    348   M2K5_ARATH Mitogen-activated protein kinase k...2322e-26     117     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009814; P:defense response, incompatible interaction; IMP:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR.
854Q751E8    303   PHO85_ASHGO Negative regulator of the PHO sys...2512e-26     116     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
855Q13153    545   PAK1_HUMAN Serine/threonine-protein kinase PA...2932e-26     119     27     50GO:0030424; C:axon; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0014704; C:intercalated disc; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048754; P:branching morphogenesis of a tube; IMP:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0042060; P:wound healing; IMP:UniProtKB.
856P38623    610   RCK2_YEAST Serine/threonine-protein kinase RC...2532e-26     120     29     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0007231; P:osmosensory signaling pathway; IMP:SGD.::GO:0040020; P:regulation of meiosis; IMP:SGD.
857Q7YQL3    559   PAK3_PONPY Serine/threonine-protein kinase PA...2932e-26     119     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.
858Q7YQL4    559   PAK3_PANTR Serine/threonine-protein kinase PA...2932e-26     119     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.
859O75914    559   PAK3_HUMAN Serine/threonine-protein kinase PA...2932e-26     119     27     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; TAS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0050808; P:synapse organization; TAS:UniProtKB.
860Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...3582e-26     121     28     46GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
861A2CG49    2964   KALRN_MOUSE Kalirin OS=Mus musculus (Mouse). ...2642e-26     122     29     52GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
862Q08E52    544   PAK1_BOVIN Serine/threonine-protein kinase PA...2932e-26     119     27     50GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB.
863Q8WZ42    34350   TITIN_HUMAN Titin OS=Homo sapiens (Human). GN...2472e-26     122     28     54GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031430; C:M band; IDA:BHF-UCL.::GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.::GO:0031433; F:telethonin binding; ISS:BHF-UCL.
GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.::GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL.::GO:0045214; P:sarcomere organization; IMP:BHF-UCL.::GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.::GO:0006941; P:striated muscle contraction; TAS:UniProtKB.
864Q04770    291   CDK2_ENTHI Cell division protein kinase 2 hom...2463e-26     116     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
865Q55CA6    635   Y0146_DICDI Probable serine/threonine-protein...3123e-26     119     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
866Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...2124e-26     119     29     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
867Q7Z8E9    914   STE20_MAGO7 Serine/threonine-protein kinase M...2404e-26     120     31     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
868Q05513    592   KPCZ_HUMAN Protein kinase C zeta type OS=Homo...2894e-26     119     29     49GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IC:BHF-UCL.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.::GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:2001181; P:positive regulation of interleukin-10 secretion; ISS:UniProtKB.::GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.::GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:UniProtKB.
869A2AAJ9    8891   OBSCN_MOUSE Obscurin OS=Mus musculus (Mouse)....1730.0000006     58.5     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
870Q19266    597   KPC3_CAEEL Protein kinase C-like 3 OS=Caenorh...3245e-26     119     27     48GO:0016324; C:apical plasma membrane; IDA:WormBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
871Q90XF2    588   KPCI_DANRE Protein kinase C iota type OS=Dani...3095e-26     118     27     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031226; C:intrinsic to plasma membrane; IDA:ZFIN.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005915; C:zonula adherens; IDA:ZFIN.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034334; P:adherens junction maintenance; IMP:ZFIN.::GO:0045217; P:cell-cell junction maintenance; IMP:ZFIN.::GO:0007502; P:digestive tract mesoderm development; IMP:ZFIN.::GO:0048546; P:digestive tract morphogenesis; IMP:ZFIN.::GO:0021744; P:dorsal motor nucleus of vagus nerve development; IMP:ZFIN.::GO:0035050; P:embryonic heart tube development; IMP:ZFIN.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; IMP:ZFIN.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IMP:ZFIN.::GO:0008078; P:mesodermal cell migration; IMP:ZFIN.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:ZFIN.::GO:0001841; P:neural tube formation; IGI:ZFIN.::GO:0007405; P:neuroblast proliferation; IMP:ZFIN.::GO:0007097; P:nuclear migration; IMP:ZFIN.::GO:0042476; P:odontogenesis; IMP:ZFIN.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN.
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