rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P34248 | 587 | YKK0_YEAST Probable intramembrane protease YK... | 587 | 0 | 1195 | 100 | 100 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | Q9UTA3 | 295 | YL8H_SCHPO Probable intramembrane protease C2... | 201 | 3e-32 | 130 | 36 | 58 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:PomBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | P49049 | 468 | IMP2_CAEEL Intramembrane protease 2 OS=Caenor... | 208 | 9e-32 | 131 | 35 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | Q8TCT9 | 377 | HM13_HUMAN Minor histocompatibility antigen H... | 244 | 3e-26 | 114 | 30 | 51 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB. | 5 | Q9D8V0 | 378 | HM13_MOUSE Minor histocompatibility antigen H... | 215 | 7e-26 | 113 | 33 | 53 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; ISS:UniProtKB. | 6 | Q5F383 | 596 | SPP2B_CHICK Signal peptide peptidase-like 2B ... | 219 | 4e-22 | 104 | 31 | 51 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 7 | Q3TD49 | 578 | SPP2B_MOUSE Signal peptide peptidase-like 2B ... | 231 | 2e-21 | 102 | 29 | 48 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 8 | Q5PQL3 | 577 | SPP2B_RAT Signal peptide peptidase-like 2B OS... | 228 | 3e-21 | 101 | 29 | 50 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 9 | Q8TCT6 | 385 | SPPL3_HUMAN Signal peptide peptidase-like 3 O... | 233 | 8e-20 | 95.1 | 29 | 50 | GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q9CUS9 | 384 | SPPL3_MOUSE Signal peptide peptidase-like 3 O... | 233 | 1e-19 | 94.7 | 29 | 50 | GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q8TCT7 | 592 | SPP2B_HUMAN Signal peptide peptidase-like 2B ... | 228 | 6e-19 | 94 | 30 | 51 | GO:0010008; C:endosome membrane; IDA:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.::GO:0050776; P:regulation of immune response; IMP:UniProtKB. | 12 | Q9JJF9 | 523 | SPP2A_MOUSE Signal peptide peptidase-like 2A ... | 192 | 9e-16 | 84 | 28 | 47 | GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IDA:MGI.::GO:0005765; C:lysosomal membrane; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 13 | Q8TCT8 | 520 | SPP2A_HUMAN Signal peptide peptidase-like 2A ... | 192 | 0.000000000000002 | 82.8 | 31 | 49 | GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.::GO:0050776; P:regulation of immune response; IMP:UniProtKB. | 14 | A2A6C4 | 690 | SPP2C_MOUSE Signal peptide peptidase-like 2C ... | 274 | 0.000000000000003 | 82.8 | 26 | 45 | GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | Q8IUH8 | 684 | SPP2C_HUMAN Signal peptide peptidase-like 2C ... | 269 | 0.00000000000008 | 78.2 | 26 | 44 | GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | P38925 | 575 | SMF1_YEAST Manganese transporter SMF1 OS=Sacc... | 70 | 3.4 | 34.3 | 36 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0022890; F:inorganic cation transmembrane transporter activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015295; F:solute:hydrogen symporter activity; IDA:SGD. | | | | | | | | | | GO:0015691; P:cadmium ion transport; IGI:SGD.::GO:0006876; P:cellular cadmium ion homeostasis; IGI:SGD.::GO:0006878; P:cellular copper ion homeostasis; IGI:SGD.::GO:0030026; P:cellular manganese ion homeostasis; IMP:SGD.::GO:0006825; P:copper ion transport; IGI:SGD.::GO:0006828; P:manganese ion transport; IMP:SGD. | 17 | P25847 | 964 | MSH2_YEAST DNA mismatch repair protein MSH2 O... | 115 | 5.7 | 33.9 | 30 | 44 | GO:0032301; C:MutSalpha complex; IPI:SGD.::GO:0032302; C:MutSbeta complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:SGD.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IDA:SGD.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IMP:SGD.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IMP:SGD. | 18 | O46107 | 439 | LIP1_DROME Lipase 1 OS=Drosophila melanogaste... | 132 | 9 | 32.7 | 23 | 42 | GO:0005576; C:extracellular region; NAS:UniProtKB. | | | | | | | | | | GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro. | | | | | | | | | | GO:0007586; P:digestion; IEP:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 19 | Q0UDH1 | 382 | CTU2_PHANO Cytoplasmic tRNA 2-thiolation prot... | 79 | 9 | 32.7 | 27 | 44 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0000049; F:tRNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0034227; P:tRNA thio-modification; ISS:UniProtKB.::GO:0002098; P:tRNA wobble uridine modification; ISS:UniProtKB. |