Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL092C
Length:
1104
Number of sequences:
5887
Description:
YKL092C BUD2 SGDID:S000001575, Chr XI from 269459-266145, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33314    1104   BUD2_YEAST Inhibitory regulator protein BUD2/...11040     2234     100     100GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0030447; P:filamentous growth; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
2Q8MLZ5    1207   GAP2_CAEEL Ras GTPase-activating protein gap-...4032e-27     124     28     47GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; NAS:UniProtKB.
GO:0046580; P:negative regulation of Ras protein signal transduction; IEP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007165; P:signal transduction; IEA:InterPro.
3Q54Y08    877   NGAP_DICDI Probable Ras GTPase-activating-lik...2113e-27     123     33     56GO:0005813; C:centrosome; TAS:dictyBase.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro.
4Q8T498    1580   GAP2_DROME Probable Ras GTPase-activating pro...2345e-27     123     31     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
5Q9UJF2    1139   NGAP_HUMAN Ras GTPase-activating protein nGAP...4725e-27     122     25     45GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; TAS:ProtInc.
6Q5VWQ8    1189   DAB2P_HUMAN Disabled homolog 2-interacting pr...4373e-26     120     23     47GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0071889; F:14-3-3 protein binding; IDA:BHF-UCL.::GO:0005123; F:death receptor binding; IPI:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0051721; F:protein phosphatase 2A binding; IDA:BHF-UCL.::GO:0005099; F:Ras GTPase activator activity; ISS:BHF-UCL.::GO:0035591; F:signaling adaptor activity; IDA:BHF-UCL.
GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:BHF-UCL.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; ISS:BHF-UCL.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0010633; P:negative regulation of epithelial cell migration; TAS:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0034261; P:negative regulation of Ras GTPase activity; IMP:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
7Q3UHC7    1189   DAB2P_MOUSE Disabled homolog 2-interacting pr...3731e-25     118     25     48GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IMP:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
8Q6P730    996   DAB2P_RAT Disabled homolog 2-interacting prot...4351e-25     118     23     47GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0047485; F:protein N-terminus binding; IPI:RGD.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD.
GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:RGD.
9P50904    1038   RASA1_RAT Ras GTPase-activating protein 1 OS=...4582e-25     117     23     47GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
10P20936    1047   RASA1_HUMAN Ras GTPase-activating protein 1 O...4544e-24     113     23     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0001948; F:glycoprotein binding; IPI:UniProtKB.::GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019870; F:potassium channel inhibitor activity; NAS:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.::GO:0005102; F:receptor binding; IPI:UniProtKB.
GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; NAS:UniProtKB.::GO:0051252; P:regulation of RNA metabolic process; NAS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
11P09851    1044   RASA1_BOVIN Ras GTPase-activating protein 1 O...4541e-23     112     23     46GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome.
GO:0051020; F:GTPase binding; ISS:AgBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome.::GO:0005102; F:receptor binding; ISS:AgBase.
GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:AgBase.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:AgBase.::GO:0030833; P:regulation of actin filament polymerization; ISS:AgBase.::GO:0007165; P:signal transduction; ISS:AgBase.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.
12Q9Z268    799   RASL1_MOUSE RasGAP-activating-like protein 1 ...4387e-23     108     22     43GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
13Q8C2K5    1041   RASL3_MOUSE RAS protein activator like-3 OS=M...4223e-21     104     21     41GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro.
14A6QQ91    1012   RASL3_BOVIN RAS protein activator like-3 OS=B...3944e-20     100     22     41GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome.
GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro.
15O95294    804   RASL1_HUMAN RasGAP-activating-like protein 1 ...4066e-20     99.8     23     43GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
16Q96PV0    1343   SYGP1_HUMAN Ras GTPase-activating protein Syn...2342e-19     98.6     27     52GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.
17Q9QUH6    1308   SYGP1_RAT Ras GTPase-activating protein SynGA...2342e-19     98.2     27     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB.
18F6SEU4    1340   SYGP1_MOUSE Ras GTPase-activating protein Syn...2342e-19     98.2     27     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0016358; P:dendrite development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0050771; P:negative regulation of axonogenesis; IDA:MGI.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0043408; P:regulation of MAPK cascade; IMP:MGI.::GO:0050803; P:regulation of synapse structure and activity; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
19P48423    1163   GAP1_DROME GTPase-activating protein OS=Droso...3554e-19     97.4     23     44GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IMP:FlyBase.
GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IMP:FlyBase.::GO:0007062; P:sister chromatid cohesion; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; NAS:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase.
20Q63713    847   RASA2_RAT Ras GTPase-activating protein 2 OS=...1496.6     34.7     27     44GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
21Q9QYJ2    834   RASA3_RAT Ras GTPase-activating protein 3 OS=...2327e-19     96.3     29     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
22Q60790    834   RASA3_MOUSE Ras GTPase-activating protein 3 O...2327e-19     96.3     29     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
23Q28013    834   RASA3_BOVIN Ras GTPase-activating protein 3 O...2001e-18     95.9     28     51GO:0005737; C:cytoplasm; ISS:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; ISS:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; ISS:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:RefGenome.
24Q86YV0    1011   RASL3_HUMAN RAS protein activator like-3 OS=H...4361e-18     95.9     21     41GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro.
25C9J798    803   RAS4B_HUMAN Putative Ras GTPase-activating pr...4403e-18     94     24     44GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
26O43374    803   RASL2_HUMAN Ras GTPase-activating protein 4 O...4406e-18     93.2     24     44GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
27P58069    848   RASA2_MOUSE Ras GTPase-activating protein 2 O...1497.6     34.3     27     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
28Q14644    834   RASA3_HUMAN Ras GTPase-activating protein 3 O...2001e-17     92     27     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:BHF-UCL.
GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
29Q15283    849   RASA2_HUMAN Ras GTPase-activating protein 2 O...1499.4     33.9     28     43GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
30Q6PFQ7    802   RASL2_MOUSE Ras GTPase-activating protein 4 O...4722e-16     88.6     22     44GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
31Q55AR6    920   NFAA_DICDI Neurofibromin-A OS=Dictyostelium d...2190.0000000000002     78.2     29     52GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005099; F:Ras GTPase activator activity; ISS:dictyBase.
GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0030833; P:regulation of actin filament polymerization; IMP:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
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