Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL088W
Length:
571
Number of sequences:
5887
Description:
YKL088W CAB3 SGDID:S000001571, Chr XI from 275283-276998, Genome Release 64-1-1, Verified ORF, "Subunit of a phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaBC"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36076    571   CAB3_YEAST Coenzyme A biosynthesis protein 3 ...5710     1176     100     100GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015937; P:coenzyme A biosynthetic process; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
2Q9UTI7    625   TYSY_SCHPO Probable thymidylate synthase OS=S...2397e-52     192     43     61GO:0005829; C:cytosol; IDA:PomBase.
GO:0004799; F:thymidylate synthase activity; ISS:PomBase.
GO:0006231; P:dTMP biosynthetic process; ISS:PomBase.
3Q12600    531   SIS2_CANTR Protein SIS2 OS=Candida tropicalis...2076e-51     188     46     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0003824; F:catalytic activity; IEA:InterPro.
4P36024    562   SIS2_YEAST Phosphopantothenoylcysteine decarb...2417e-45     171     37     59GO:0005634; C:nucleus; IDA:SGD.::GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IDA:SGD.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
5Q9SWE5    209   HAL3A_ARATH Phosphopantothenoylcysteine decar...1915e-38     143     42     60GO:0005829; C:cytosol; IDA:TAIR.
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:TAIR.
GO:0015937; P:coenzyme A biosynthetic process; TAS:TAIR.::GO:0042538; P:hyperosmotic salinity response; IEP:TAIR.
6Q96CD2    204   COAC_HUMAN Phosphopantothenoylcysteine decarb...1929e-38     142     41     64GO:0005829; C:cytosol; TAS:Reactome.
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; TAS:Reactome.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
7Q8BZB2    204   COAC_MOUSE Phosphopantothenoylcysteine decarb...2104e-36     138     37     60
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.
8P94063    201   HAL3B_ARATH Probable phosphopantothenoylcyste...2031e-34     134     40     60
GO:0010181; F:FMN binding; ISS:TAIR.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IGI:TAIR.
GO:0015937; P:coenzyme A biosynthetic process; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IEP:TAIR.
9Q54Y51    197   COAC_DICDI Putative phosphopantothenoylcystei...2071e-34     133     39     60
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; ISS:dictyBase.
GO:0015937; P:coenzyme A biosynthetic process; ISS:dictyBase.
10Q08438    674   VHS3_YEAST Phosphopantothenoylcysteine decarb...620.0000002     57.4     45     63GO:0071513; C:phosphopantothenoylcysteine decarboxylase complex; IDA:SGD.
GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004864; F:protein phosphatase inhibitor activity; IDA:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030004; P:cellular monovalent inorganic cation homeostasis; IPI:SGD.::GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.
11Q54433    179   COAC_STRMU Probable phosphopantothenoylcystei...1909e-20     91.7     33     54
GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
12P73881    402   COABC_SYNY3 Coenzyme A biosynthesis bifunctio...1786e-18     89.7     34     56
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
13Q5E8M6    409   COABC_VIBF1 Coenzyme A biosynthesis bifunctio...1893e-16     84.7     31     54
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
14O35033    406   COABC_BACSU Probable coenzyme A biosynthesis ...1945e-16     84     32     54
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
15O51752    390   COABC_BORBU Coenzyme A biosynthesis bifunctio...1980.000000000000002     82     29     51
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
16P44953    400   COABC_HAEIN Coenzyme A biosynthesis bifunctio...1850.000000000000004     81.3     31     51
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
17Q9KVD1    399   COABC_VIBCH Coenzyme A biosynthesis bifunctio...1830.00000000000001     79.3     32     52
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
18Q7MPS9    401   COABC_VIBVY Coenzyme A biosynthesis bifunctio...1860.00000000000001     79.3     31     53
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
19Q8DDX8    401   COABC_VIBVU Coenzyme A biosynthesis bifunctio...1860.00000000000002     79.3     31     53
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
20Q87T89    399   COABC_VIBPA Coenzyme A biosynthesis bifunctio...1860.00000000000008     77     29     52
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
21P0ABQ0    406   COABC_ECOLI Coenzyme A biosynthesis bifunctio...1850.0000000002     66.2     28     50
GO:0010181; F:FMN binding; IDA:EcoCyc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IDA:EcoCyc.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:EcoCyc.
GO:0015937; P:coenzyme A biosynthetic process; IDA:EcoCyc.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
22P0ABQ1    406   COABC_ECOL6 Coenzyme A biosynthesis bifunctio...1850.0000000002     66.2     28     50
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
23P30197    181   EPID_STAEP Epidermin decarboxylase OS=Staphyl...740.00002     48.5     39     59
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
24Q9RC23    194   MRSD_BACSY Mersacidin decarboxylase OS=Bacill...840.002     43.1     35     56
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
GO:0017000; P:antibiotic biosynthetic process; IDA:UniProtKB.
25P67733    418   COABC_MYCTU Coenzyme A biosynthesis bifunctio...1890.002     44.3     25     48GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:MTBBASE.
GO:0015937; P:coenzyme A biosynthetic process; IDA:MTBBASE.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
26P67734    418   COABC_MYCBO Coenzyme A biosynthesis bifunctio...1890.002     44.3     25     48
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
27Q58323    403   COABC_METJA Coenzyme A biosynthesis bifunctio...1510.013     42     25     50
GO:0010181; F:FMN binding; IEA:InterPro.::GO:0004632; F:phosphopantothenate--cysteine ligase activity; IEA:EC.::GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IEA:EC.
GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.::GO:0015941; P:pantothenate catabolic process; IEA:InterPro.
28Q58140    186   Y730_METJA Uncharacterized protein MJ0730 OS=...1470.04     39.3     31     50
GO:0003824; F:catalytic activity; IEA:InterPro.
29Q26768    243   AGI6_TRYBB I/6 autoantigen OS=Trypanosoma bru...670.078     38.9     39     66GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.
30Q6UVJ0    657   SAS6_HUMAN Spindle assembly abnormal protein ...2020.99     36.2     28     47GO:0005814; C:centriole; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007099; P:centriole replication; IMP:UniProtKB.
31Q751Y8    694   LCD1_ASHGO DNA damage checkpoint protein LCD1...1206.2     33.5     23     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
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