Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL085W
Length:
334
Number of sequences:
5887
Description:
YKL085W MDH1 SGDID:S000001568, Chr XI from 279123-280127, Genome Release 64-1-1, Verified ORF, "Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P17505    334   MDHM_YEAST Malate dehydrogenase, mitochondria...3340     674     100     100GO:0005759; C:mitochondrial matrix; IDA:SGD.
GO:0030060; F:L-malate dehydrogenase activity; IDA:SGD.::GO:0003729; F:mRNA binding; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0001300; P:chronological cell aging; IMP:SGD.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0006099; P:tricarboxylic acid cycle; IMP:SGD.
2Q9Y7R8    341   MDHM_SCHPO Malate dehydrogenase, mitochondria...3311e-132     389     60     75GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0030060; F:L-malate dehydrogenase activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006108; P:malate metabolic process; ISS:PomBase.::GO:0006099; P:tricarboxylic acid cycle; ISS:PomBase.
3P83373    339   MDHM_FRAAN Malate dehydrogenase, mitochondria...3302e-110     332     56     69GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
4P83778    337   MDHC_CANAL Malate dehydrogenase, cytoplasmic ...3325e-108     325     52     72GO:0005739; C:mitochondrion; NAS:CGD.::GO:0005625; C:soluble fraction; IDA:CGD.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; NAS:CGD.
5Q5NVR2    338   MDHM_PONAB Malate dehydrogenase, mitochondria...3302e-107     324     54     68GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
6Q4R568    338   MDHM_MACFA Malate dehydrogenase, mitochondria...3303e-107     323     54     68GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
7P40926    338   MDHM_HUMAN Malate dehydrogenase, mitochondria...3305e-107     323     54     68GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0030060; F:L-malate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.::GO:0006108; P:malate metabolic process; IDA:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
8P00346    338   MDHM_PIG Malate dehydrogenase, mitochondrial ...3261e-106     322     54     68GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
9Q32LG3    338   MDHM_BOVIN Malate dehydrogenase, mitochondria...3262e-106     322     54     68GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
10P04636    338   MDHM_RAT Malate dehydrogenase, mitochondrial ...3265e-106     320     54     68GO:0005759; C:mitochondrial matrix; IDA:RGD.
GO:0030060; F:L-malate dehydrogenase activity; IDA:RGD.::GO:0046554; F:malate dehydrogenase (NADP+) activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043621; F:protein self-association; IDA:RGD.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006108; P:malate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD.
11O02640    341   MDHM_CAEEL Probable malate dehydrogenase, mit...3142e-105     318     54     72GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; ISS:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006108; P:malate metabolic process; ISS:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
12P08249    338   MDHM_MOUSE Malate dehydrogenase, mitochondria...3263e-105     318     53     68GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006475; P:internal protein amino acid acetylation; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
13Q42972    356   MDHG_ORYSJ Malate dehydrogenase, glyoxysomal ...3153e-104     316     54     70GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
14P17783    347   MDHM_CITLA Malate dehydrogenase, mitochondria...3133e-104     316     56     68GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
15Q9SN86    403   MDHP_ARATH Malate dehydrogenase, chloroplasti...3256e-103     315     54     69GO:0048046; C:apoplast; IDA:TAIR.::GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0010319; C:stromule; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0030060; F:L-malate dehydrogenase activity; IDA:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
16Q9ZP06    341   MDHM1_ARATH Malate dehydrogenase 1, mitochond...3271e-102     312     54     67GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0030060; F:L-malate dehydrogenase activity; IMP:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0042742; P:defense response to bacterium; IEP:TAIR.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
17Q9LKA3    341   MDHM2_ARATH Malate dehydrogenase 2, mitochond...3253e-102     310     52     67GO:0048046; C:apoplast; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005507; F:copper ion binding; IDA:TAIR.::GO:0030060; F:L-malate dehydrogenase activity; IGI:TAIR.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0042742; P:defense response to bacterium; IEP:TAIR.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
18P37228    353   MDHG_SOYBN Malate dehydrogenase, glyoxysomal ...3151e-101     310     52     69GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
19P19446    356   MDHG_CITLA Malate dehydrogenase, glyoxysomal ...3174e-101     308     51     69GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
20O82399    354   MDHG2_ARATH Probable malate dehydrogenase, gl...3306e-101     308     51     68GO:0009507; C:chloroplast; IDA:TAIR.::GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0031998; P:regulation of fatty acid beta-oxidation; IGI:TAIR.::GO:0080093; P:regulation of photorespiration; IMP:TAIR.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
21P46488    356   MDHG_CUCSA Malate dehydrogenase, glyoxysomal ...3152e-100     306     51     69GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
22P46487    347   MDHM_EUCGU Malate dehydrogenase, mitochondria...3252e-99     304     52     66GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
23Q42686    373   MDHM_CHLRE Malate dehydrogenase, mitochondria...3143e-99     304     53     67GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
24Q43744    341   MDHM_BRANA Malate dehydrogenase, mitochondria...3251e-95     294     50     66GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
25Q8DEC2    310   MDH_VIBVU Malate dehydrogenase OS=Vibrio vuln...3157e-95     291     52     66
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
26A0L113    311   MDH_SHESA Malate dehydrogenase OS=Shewanella ...3151e-94     290     51     66
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
27Q43743    358   MDHG1_BRANA Malate dehydrogenase 1, glyoxysom...3182e-94     291     53     69GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
28A1S3C4    311   MDH_SHEAM Malate dehydrogenase OS=Shewanella ...3152e-94     289     51     65
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
29B4F2A1    312   MDH_PROMH Malate dehydrogenase OS=Proteus mir...3152e-94     290     51     66
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
30Q0HZ38    311   MDH_SHESR Malate dehydrogenase OS=Shewanella ...3153e-94     289     51     65
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
31Q0HEW2    311   MDH_SHESM Malate dehydrogenase OS=Shewanella ...3153e-94     289     51     65
GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
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