Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL073W
Length:
881
Number of sequences:
5887
Description:
YKL073W LHS1 SGDID:S000001556, Chr XI from 296430-299075, Genome Release 64-1-1, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P36016    881   LHS1_YEAST Heat shock protein 70 homolog LHS1...8810     1797     100     100GO:0005788; C:endoplasmic reticulum lumen; IDA:SGD.
GO:0000774; F:adenyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005524; F:ATP binding; IMP:SGD.::GO:0016887; F:ATPase activity; IEA:EC.::GO:0051082; F:unfolded protein binding; IGI:SGD.
GO:0031204; P:posttranslational protein targeting to membrane, translocation; IMP:SGD.::GO:0006986; P:response to unfolded protein; IGI:SGD.
2Q6FU50    889   LHS1_CANGA Heat shock protein 70 homolog LHS1...8380     565     39     61GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.
3Q10061    848   YAM6_SCHPO Heat shock protein 70 homolog OS=S...7304e-67     244     29     48GO:0005788; C:endoplasmic reticulum lumen; ISS:PomBase.
GO:0000774; F:adenyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0034620; P:cellular response to unfolded protein; ISS:PomBase.::GO:0061077; P:chaperone-mediated protein folding; NAS:PomBase.::GO:0031204; P:posttranslational protein targeting to membrane, translocation; ISS:PomBase.
4Q566I3    646   HYOU1_XENLA Hypoxia up-regulated protein 1 OS...5841e-57     214     29     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
5Q5ZLK7    1002   HYOU1_CHICK Hypoxia up-regulated protein 1 OS...5004e-57     216     29     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
6Q7ZUW2    980   HYOU1_DANRE Hypoxia up-regulated protein 1 OS...4775e-57     215     31     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
7Q9Y4L1    999   HYOU1_HUMAN Hypoxia up-regulated protein 1 OS...5511e-56     214     29     51GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
8Q63617    999   HYOU1_RAT Hypoxia up-regulated protein 1 OS=R...5552e-55     211     29     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0001666; P:response to hypoxia; IDA:RGD.
9Q9JKR6    999   HYOU1_MOUSE Hypoxia up-regulated protein 1 OS...5554e-55     210     29     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
10Q0VA61    643   HYOU1_XENTR Hypoxia up-regulated protein 1 OS...5714e-54     202     28     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
11Q60432    999   HYOU1_CRIGR Hypoxia up-regulated protein 1 OS...4775e-53     203     29     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
12F4JMJ1    867   HSP7R_ARATH Heat shock 70 kDa protein 17 OS=A...8252e-36     152     23     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
13P17066    643   HSP76_HUMAN Heat shock 70 kDa protein 6 OS=Ho...5831e-34     144     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; TAS:ProtInc.
14P25840    650   HSP70_CHLRE Heat shock 70 kDa protein OS=Chla...5873e-34     143     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
15Q9N1U2    643   HSP76_SAGOE Heat shock 70 kDa protein 6 OS=Sa...5808e-34     142     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
16Q96VB9    701   HSP7F_CANAL Heat shock protein homolog SSE1 O...4982e-33     141     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
17Q05944    654   HSP70_HYDVU Heat shock 70 kDa protein OS=Hydr...6203e-33     140     23     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
18P18694    645   HSP72_USTMA Heat shock 70 kDa protein 2 OS=Us...5813e-33     140     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
19P16019    646   HSP70_THEAN Heat shock 70 kDa protein OS=Thei...5897e-33     139     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
20P37899    649   HSP70_PYRSA Heat shock 70 kDa protein OS=Pyre...5911e-32     138     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
21Q27031    647   HSP70_THEPA Heat shock 70 kDa protein OS=Thei...5891e-32     138     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
22Q556U6    926   BIP1_DICDI Luminal-binding protein 1 OS=Dicty...4762e-32     139     26     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
23P10591    642   HSP71_YEAST Heat shock protein SSA1 OS=Saccha...5055e-32     136     26     46GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0051082; F:unfolded protein binding; IDA:SGD.
GO:0002181; P:cytoplasmic translation; IMP:SGD.::GO:0000060; P:protein import into nucleus, translocation; IDA:SGD.::GO:0042026; P:protein refolding; IDA:SGD.::GO:0006626; P:protein targeting to mitochondrion; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IDA:SGD.
24Q04967    643   HSP76_PIG Heat shock 70 kDa protein 6 OS=Sus ...5806e-32     136     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
25P36415    640   HS7C1_DICDI Heat shock cognate 70 kDa protein...5847e-32     136     24     46GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.
26Q9I8F9    639   HSP71_ORYLA Heat shock 70 kDa protein 1 OS=Or...6477e-32     136     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
27Q9U639    652   HSP7D_MANSE Heat shock 70 kDa protein cognate...5801e-31     135     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
28Q05746    686   HSP70_PLACB Heat shock 70 kDa protein OS=Plas...5872e-31     135     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
29Q557E0    632   HS7C2_DICDI Heat shock cognate 70 kDa protein...6022e-31     134     24     44GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
30P22202    642   HSP74_YEAST Heat shock protein SSA4 OS=Saccha...5982e-31     134     24     45GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006950; P:response to stress; IDA:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
31O59855    647   HSP72_SCHPO Probable heat shock protein ssa2 ...5882e-31     134     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0034605; P:cellular response to heat; IEP:PomBase.::GO:0061077; P:chaperone-mediated protein folding; NAS:PomBase.::GO:0042026; P:protein refolding; ISS:PomBase.
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