Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL073W
Length:
881
Number of sequences:
5887
Description:
YKL073W LHS1 SGDID:S000001556, Chr XI from 296430-299075, Genome Release 64-1-1, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P08106    634   HSP70_CHICK Heat shock 70 kDa protein OS=Gall...3574e-28     124     27     50GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009408; P:response to heat; IDA:AgBase.
92P08108    651   HSP70_ONCMY Heat shock cognate 70 kDa protein...5874e-28     124     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
93P06761    654   GRP78_RAT 78 kDa glucose-regulated protein OS...6624e-28     124     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IPI:RGD.
94P05456    680   HSP70_TRYCR Heat shock 70 kDa protein OS=Tryp...5844e-28     124     22     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
95Q9GSU4    643   HSP72_DROSI Major heat shock 70 kDa protein B...5704e-28     124     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
96P27420    661   HSP7C_CAEEL Heat shock 70 kDa protein C OS=Ca...6695e-28     124     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0009306; P:protein secretion; ISS:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
97A5A8V7    641   HS71L_PIG Heat shock 70 kDa protein 1-like OS...4255e-28     124     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
98P78695    661   GRP78_NEUCR 78 kDa glucose-regulated protein ...6735e-28     124     24     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
99P63018    646   HSP7C_RAT Heat shock cognate 71 kDa protein O...5025e-28     124     25     45GO:0070062; C:extracellular vesicular exosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0042623; F:ATPase activity, coupled; IDA:RGD.::GO:0005102; F:receptor binding; IPI:RGD.::GO:0051082; F:unfolded protein binding; IMP:RGD.
GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100P63017    646   HSP7C_MOUSE Heat shock cognate 71 kDa protein...5025e-28     124     25     45GO:0005829; C:cytosol; IDA:MGI.::GO:0070062; C:extracellular vesicular exosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IDA:MGI.::GO:0051082; F:unfolded protein binding; IPI:MGI.
GO:0051085; P:chaperone mediated protein folding requiring cofactor; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
101Q6BZH1    683   GRP78_DEBHA 78 kDa glucose-regulated protein ...6496e-28     124     24     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
102P0CB32    641   HS71L_BOVIN Heat shock 70 kDa protein 1-like ...4256e-28     124     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
103Q03685    668   BIP5_TOBAC Luminal-binding protein 5 OS=Nicot...6577e-28     124     22     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
104P29357    653   HSP7E_SPIOL Chloroplast envelope membrane 70 ...5937e-28     123     22     43GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
105P19378    646   HSP7C_CRIGR Heat shock cognate 71 kDa protein...5021e-27     123     25     45GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106P34931    641   HS71L_HUMAN Heat shock 70 kDa protein 1-like ...5831e-27     122     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; TAS:ProtInc.
107Q9LKR3    669   HSP7K_ARATH Heat shock 70 kDa protein 11 OS=A...6781e-27     122     22     42GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030433; P:ER-associated protein catabolic process; IMP:TAIR.::GO:0010197; P:polar nucleus fusion; IGI:TAIR.
108Q9VG58    641   HSP74_DROME Major heat shock 70 kDa protein B...5512e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.
109P02825    642   HSP71_DROME Major heat shock 70 kDa protein A...5702e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IEP:FlyBase.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
110P82910    642   HSP70_DROME Major heat shock 70 kDa protein A...5702e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
111P17804    653   HSP70_LEIDO Heat shock 70 kDa protein OS=Leis...5812e-27     122     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
112Q96W30    654   HSP72_PARBA Heat shock 70 kDa protein 2 OS=Pa...5823e-27     122     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
113Q9BIR7    641   HSP75_DROME Major heat shock 70 kDa protein B...5513e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.::GO:0031427; P:response to methotrexate; IEP:FlyBase.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
114Q9BIS2    641   HSP73_DROME Major heat shock 70 kDa protein B...5513e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IEP:FlyBase.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
115Q8INI8    641   HSP72_DROME Major heat shock 70 kDa protein B...5513e-27     122     24     45GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0035080; P:heat shock-mediated polytene chromosome puffing; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
116Q10284    613   HSP75_SCHPO Heat shock protein sks2 OS=Schizo...3633e-27     121     26     48GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0051083; P:'de novo' cotranslational protein folding; ISS:PomBase.::GO:0033554; P:cellular response to stress; NAS:PomBase.::GO:0061077; P:chaperone-mediated protein folding; NAS:PomBase.::GO:0002181; P:cytoplasmic translation; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
117P27322    644   HSP72_SOLLC Heat shock cognate 70 kDa protein...5853e-27     122     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
118Q91291    645   HSP70_PLEWA Heat shock 70 kDa protein OS=Pleu...5853e-27     122     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
119P36604    663   GRP78_SCHPO 78 kDa glucose-regulated protein ...6433e-27     121     25     44GO:0005788; C:endoplasmic reticulum lumen; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0051084; P:'de novo' posttranslational protein folding; IDA:PomBase.::GO:0034620; P:cellular response to unfolded protein; ISS:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.
120P40918    643   HSP70_DAVTA Heat shock 70 kDa protein OS=Davi...5883e-27     121     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
121Q07437    652   HSP70_LEIAM Heat shock 70 kDa protein OS=Leis...5813e-27     121     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
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