Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL073W
Length:
881
Number of sequences:
5887
Description:
YKL073W LHS1 SGDID:S000001556, Chr XI from 296430-299075, Genome Release 64-1-1, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q01233    646   HSP70_NEUCR Heat shock 70 kDa protein OS=1257...6023e-29     127     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
62P48720    649   HSP70_BLAEM Heat shock 70 kDa protein OS=Blas...5843e-29     127     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
63Q9TUG3    636   HSP72_CAPHI Heat shock-related 70 kDa protein...3614e-29     127     27     49GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
64P09189    651   HSP7C_PETHY Heat shock cognate 70 kDa protein...5864e-29     127     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
65Q90593    652   GRP78_CHICK 78 kDa glucose-regulated protein ...6876e-29     127     23     42GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
66P11143    645   HSP70_MAIZE Heat shock 70 kDa protein OS=Zea ...5848e-29     126     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
67P49118    666   BIP_SOLLC Luminal-binding protein OS=Solanum ...6778e-29     126     22     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
68P22954    653   HSP7B_ARATH Heat shock 70 kDa protein 2 OS=Ar...5829e-29     126     23     44GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.
69Q91883    658   GRP78_XENLA 78 kDa glucose-regulated protein ...6811e-28     126     23     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
70Q0VCX2    655   GRP78_BOVIN 78 kDa glucose-regulated protein ...6841e-28     126     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
71Q06248    639   HSP74_PARLI Heat shock 70 kDa protein IV OS=P...6041e-28     125     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
72Q03684    667   BIP4_TOBAC Luminal-binding protein 4 OS=Nicot...6752e-28     125     22     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
73P46587    645   HSP72_CANAL Heat shock protein SSA2 OS=Candid...5802e-28     125     24     45GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0030446; C:hyphal cell wall; IDA:CGD.::GO:0005624; C:membrane fraction; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IMP:CGD.
GO:0051701; P:interaction with host; ISS:CGD.::GO:0015833; P:peptide transport; IMP:CGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0009636; P:response to toxin; IMP:CGD.
74P27541    644   HSP70_BRUMA Heat shock 70 kDa protein OS=Brug...5812e-28     125     23     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
75P11147    651   HSP7D_DROME Heat shock 70 kDa protein cognate...6562e-28     125     23     43GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051087; F:chaperone binding; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007413; P:axonal fasciculation; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007269; P:neurotransmitter secretion; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0016246; P:RNA interference; IMP:FlyBase.::GO:0016192; P:vesicle-mediated transport; IMP:FlyBase.
76P07823    654   GRP78_MESAU 78 kDa glucose-regulated protein ...6842e-28     125     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
77Q3S4T7    654   GRP78_SPETR 78 kDa glucose-regulated protein ...6832e-28     125     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
78P11021    654   GRP78_HUMAN 78 kDa glucose-regulated protein ...6842e-28     125     23     42GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0034663; C:endoplasmic reticulum chaperone complex; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0051087; F:chaperone binding; TAS:BHF-UCL.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.::GO:0030674; F:protein binding, bridging; NAS:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; TAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0060904; P:regulation of protein folding in endoplasmic reticulum; TAS:BHF-UCL.
79P20029    655   GRP78_MOUSE 78 kDa glucose-regulated protein ...6612e-28     125     23     42GO:0009986; C:cell surface; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; IDA:BHF-UCL.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051787; F:misfolded protein binding; IDA:BHF-UCL.::GO:0043022; F:ribosome binding; IDA:MGI.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IMP:BHF-UCL.::GO:0021680; P:cerebellar Purkinje cell layer development; IMP:BHF-UCL.::GO:0021589; P:cerebellum structural organization; IMP:BHF-UCL.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IGI:MGI.::GO:0040019; P:positive regulation of embryonic development; TAS:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IMP:BHF-UCL.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
80Q5R4P0    654   GRP78_PONAB 78 kDa glucose-regulated protein ...6842e-28     125     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
81P24629    650   HSP71_SOLLC Heat shock cognate 70 kDa protein...5862e-28     125     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
82Q24789    665   HSP70_ECHGR Heat shock cognate 70 kDa protein...5833e-28     125     22     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
83Q5NVM9    646   HSP7C_PONAB Heat shock cognate 71 kDa protein...5783e-28     125     23     44GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
84P19208    661   HSP7C_CAEBR Heat shock 70 kDa protein C OS=Ca...6693e-28     125     23     42GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
85Q71U34    646   HSP7C_SAGOE Heat shock cognate 71 kDa protein...5783e-28     124     23     44GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
86P11142    646   HSP7C_HUMAN Heat shock cognate 71 kDa protein...5783e-28     124     23     44GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0006457; P:protein folding; NAS:UniProtKB.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87A2Q0Z1    646   HSP7C_HORSE Heat shock cognate 71 kDa protein...5783e-28     124     23     44GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
88P19120    650   HSP7C_BOVIN Heat shock cognate 71 kDa protein...5783e-28     124     23     44GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89P11145    661   HSP74_TRYBB Heat shock 70 kDa protein 4 OS=Tr...5863e-28     124     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
90Q4R888    641   HS71L_MACFA Heat shock 70 kDa protein 1-like ...5814e-28     124     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
91P08106    634   HSP70_CHICK Heat shock 70 kDa protein OS=Gall...3574e-28     124     27     50GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009408; P:response to heat; IDA:AgBase.
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