Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL073W
Length:
881
Number of sequences:
5887
Description:
YKL073W LHS1 SGDID:S000001556, Chr XI from 296430-299075, Genome Release 64-1-1, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O59855    647   HSP72_SCHPO Probable heat shock protein ssa2 ...5882e-31     134     24     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0034605; P:cellular response to heat; IEP:PomBase.::GO:0061077; P:chaperone-mediated protein folding; NAS:PomBase.::GO:0042026; P:protein refolding; ISS:PomBase.
32P10592    639   HSP72_YEAST Heat shock protein SSA2 OS=Saccha...5052e-31     134     26     46GO:0005829; C:cytosol; IDA:SGD.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006457; P:protein folding; IDA:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
33Q9LHA8    650   HSP7D_ARATH Heat shock 70 kDa protein 4 OS=Ar...5844e-31     134     24     45GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0016567; P:protein ubiquitination; IMP:UniProtKB.::GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:UniProtKB.::GO:0009644; P:response to high light intensity; IEP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IEP:TAIR.::GO:0009615; P:response to virus; IEP:TAIR.
34P22010    679   GRP78_KLULA 78 kDa glucose-regulated protein ...6495e-31     134     25     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
35P29843    641   HSP7A_DROME Heat shock 70 kDa protein cognate...5807e-31     132     24     44GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
36P09446    640   HSP7A_CAEEL Heat shock 70 kDa protein A OS=Ca...5818e-31     132     24     45GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:WormBase.::GO:0005515; F:protein binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0009408; P:response to heat; IDA:WormBase.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:WormBase.
37O65719    649   HSP7C_ARATH Heat shock 70 kDa protein 3 OS=Ar...5881e-30     132     24     45GO:0048046; C:apoplast; IDA:TAIR.::GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002020; F:protease binding; IPI:UniProtKB.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:UniProtKB.::GO:0080167; P:response to karrikin; IEP:TAIR.::GO:0009615; P:response to virus; IEP:UniProtKB.
38P11144    681   HSP70_PLAFA Heat shock 70 kDa protein OS=Plas...5842e-30     132     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
39P09435    649   HSP73_YEAST Heat shock protein SSA3 OS=Saccha...6012e-30     131     25     45GO:0005829; C:cytosol; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IGI:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
40Q01877    648   HSP71_PUCGR Heat shock protein HSS1 OS=Puccin...5873e-30     131     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
41P16394    676   HSP70_BRELC Heat shock 70 kDa protein OS=Brem...6044e-30     131     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
42P26413    645   HSP70_SOYBN Heat shock 70 kDa protein OS=Glyc...5814e-30     130     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
43P22953    651   HSP7A_ARATH Heat shock 70 kDa protein 1 OS=Ar...5804e-30     130     22     44GO:0048046; C:apoplast; IDA:TAIR.::GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002020; F:protease binding; IPI:UniProtKB.
GO:0042742; P:defense response to bacterium; IMP:UniProtKB.::GO:0050832; P:defense response to fungus; IMP:UniProtKB.::GO:0010187; P:negative regulation of seed germination; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:TAIR.::GO:0090332; P:stomatal closure; IMP:TAIR.
44Q10265    644   HSP71_SCHPO Probable heat shock protein ssa1 ...5884e-30     130     24     44GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0002181; P:cytoplasmic translation; NAS:PomBase.::GO:0042026; P:protein refolding; ISS:PomBase.
45P54652    639   HSP72_HUMAN Heat shock-related 70 kDa protein...3615e-30     130     27     50GO:0036128; C:CatSper complex; ISS:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.
GO:0006986; P:response to unfolded protein; TAS:ProtInc.::GO:0007286; P:spermatid development; TAS:ProtInc.
46P02827    647   HSP70_XENLA Heat shock 70 kDa protein OS=Xeno...5816e-30     130     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
47Q54BE0    630   HS7C3_DICDI Heat shock cognate 70 kDa protein...5867e-30     130     23     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
48Q707X3    613   HSP75_ZYGRC Heat shock protein SSB OS=NCYC 56...4817e-30     129     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
49O74225    707   HSP88_NEUCR Heat shock protein Hsp88 OS=1257 ...4717e-30     130     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
50Q42434    668   BIP_SPIOL Luminal-binding protein OS=Spinacia...6698e-30     130     22     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
51Q91233    644   HSP70_ONCTS Heat shock 70 kDa protein OS=Onco...5811e-29     129     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
52Q9S9N1    646   HSP7E_ARATH Heat shock 70 kDa protein 5 OS=Ar...5821e-29     129     23     46GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009408; P:response to heat; IEP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.
53P41753    652   HSP70_ACHKL Heat shock 70 kDa protein OS=Achl...5941e-29     129     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
54O97125    635   HSP68_DROME Heat shock protein 68 OS=Drosophi...6311e-29     129     24     44GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0031427; P:response to methotrexate; IEP:FlyBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
55P14659    633   HSP72_RAT Heat shock-related 70 kDa protein 2...3612e-29     129     27     49GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
56P17156    633   HSP72_MOUSE Heat shock-related 70 kDa protein...3612e-29     129     27     49GO:0036128; C:CatSper complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051861; F:glycolipid binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007141; P:male meiosis I; IMP:MGI.::GO:0031662; P:positive regulation of cyclin-dependent protein kinase activity involved in G2/M; IMP:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0070194; P:synaptonemal complex disassembly; IMP:MGI.
57P34933    636   HSP72_BOVIN Heat shock-related 70 kDa protein...3612e-29     129     27     49GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
58P16627    641   HS71L_MOUSE Heat shock 70 kDa protein 1-like ...5872e-29     128     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
59Q9HG01    665   GRP78_PICAN 78 kDa glucose-regulated protein ...5972e-29     128     25     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
60P55063    641   HS71L_RAT Heat shock 70 kDa protein 1-like OS...5913e-29     127     26     45GO:0005759; C:mitochondrial matrix; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
61Q01233    646   HSP70_NEUCR Heat shock 70 kDa protein OS=1257...6023e-29     127     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
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