Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL073W
Length:
881
Number of sequences:
5887
Description:
YKL073W LHS1 SGDID:S000001556, Chr XI from 296430-299075, Genome Release 64-1-1, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q6S4N2    641   HS71B_PIG Heat shock 70 kDa protein 1B OS=Sus...5804e-26     118     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006281; P:DNA repair; ISS:AgBase.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0009408; P:response to heat; ISS:AgBase.::GO:0000723; P:telomere maintenance; ISS:AgBase.
152Q6CQ83    613   HSP75_KLULA Heat shock protein SSB OS=1267 / ...4094e-26     118     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
153Q07439    641   HSP71_RAT Heat shock 70 kDa protein 1A/1B OS=...5805e-26     117     23     44GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051059; F:NF-kappaB binding; IPI:RGD.::GO:0002020; F:protease binding; IPI:RGD.
GO:0006952; P:defense response; IDA:RGD.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:RGD.::GO:0045906; P:negative regulation of vasoconstriction; IMP:RGD.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
154P41826    640   HSP72_ANOAL Heat shock protein 70 A2 OS=Anoph...4265e-26     117     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
155P41825    640   HSP71_ANOAL Heat shock protein 70 A1 OS=Anoph...4265e-26     117     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
156Q24798    651   GRP78_ECHGR 78 kDa glucose-regulated protein ...5835e-26     117     24     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
157Q27975    641   HS71A_BOVIN Heat shock 70 kDa protein 1A OS=B...5866e-26     117     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
158Q27965    641   HS71B_BOVIN Heat shock 70 kDa protein 1B OS=B...5866e-26     117     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006281; P:DNA repair; ISS:AgBase.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0009408; P:response to heat; ISS:AgBase.::GO:0000723; P:telomere maintenance; ISS:AgBase.
159Q7YQC6    641   HSP71_CANFA Heat shock 70 kDa protein 1 OS=Ca...4747e-26     117     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
160Q8DKR6    651   DNAK1_THEEB Chaperone protein dnaK1 OS=Thermo...6137e-26     117     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
161Q5B2V1    644   HSP70_EMENI Heat shock 70 kDa protein OS=194 ...5858e-26     117     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
162Q707W3    613   HSP75_KLUDE Heat shock protein SSB OS=Kluyver...4711e-25     116     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
163O24581    663   BIP3_MAIZE Luminal-binding protein 3 OS=Zea m...6601e-25     116     23     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
164Q24895    649   GRP78_ECHMU 78 kDa glucose-regulated protein ...5831e-25     116     25     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
165P34930    641   HS71A_PIG Heat shock 70 kDa protein 1A OS=Sus...5801e-25     116     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
166P24067    663   BIP2_MAIZE Luminal-binding protein 2 OS=Zea m...6602e-25     116     23     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
167P17879    642   HS71B_MOUSE Heat shock 70 kDa protein 1B OS=M...5982e-25     116     23     44GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006281; P:DNA repair; IMP:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0009408; P:response to heat; IDA:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI.
168Q61696    641   HS71A_MOUSE Heat shock 70 kDa protein 1A OS=M...5982e-25     116     22     44GO:0005739; C:mitochondrion; ISS:MGI.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006281; P:DNA repair; IMP:MGI.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0009408; P:response to heat; IDA:MGI.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:MGI.
169P94695    631   DNAK_DEIPM Chaperone protein DnaK OS=NBRC 101...5322e-25     115     23     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
170Q5UQ49    634   HSP70_MIMIV Heat shock 70 kDa protein homolog...6332e-25     115     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
171Q16956    667   GRP78_APLCA 78 kDa glucose-regulated protein ...5823e-25     115     24     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
172A4XKA4    606   DNAK_CALS8 Chaperone protein DnaK OS=Caldicel...6593e-25     115     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
173P87222    613   HSP75_CANAW Heat shock protein SSB1 OS=Candid...3613e-25     115     26     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
174Q61699    858   HS105_MOUSE Heat shock protein 105 kDa OS=Mus...4663e-25     116     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; TAS:BHF-UCL.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; TAS:BHF-UCL.::GO:0045345; P:positive regulation of MHC class I biosynthetic process; TAS:BHF-UCL.::GO:0051135; P:positive regulation of NK T cell activation; TAS:BHF-UCL.::GO:0070507; P:regulation of microtubule cytoskeleton organization; NAS:BHF-UCL.::GO:0006986; P:response to unfolded protein; TAS:BHF-UCL.
175Q9C7X7    617   HSP7N_ARATH Heat shock 70 kDa protein 18 OS=A...5933e-25     115     22     44GO:0009941; C:chloroplast envelope; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.
176Q876N3    613   HSP75_CANGA Heat shock protein SSB OS=NRRL Y-...4764e-25     115     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
177Q875V0    685   HSP7F_NAUCC Heat shock protein homolog SSE1 O...4734e-25     115     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
178Q0IIM3    859   HS105_BOVIN Heat shock protein 105 kDa OS=Bos...4646e-25     115     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
179P26791    655   HSP70_DAUCA Heat shock 70 kDa protein OS=Dauc...5887e-25     114     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
180Q8YUA6    653   DNAK3_NOSS1 Chaperone protein dnaK3 OS=Nostoc...4737e-25     114     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
181B3ERN8    632   DNAK_AMOA5 Chaperone protein DnaK OS=Amoeboph...6377e-25     114     23     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
records
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