rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q566S6 | 309 | DRS7B_DANRE Dehydrogenase/reductase SDR famil... | 268 | 0.000000002 | 60.8 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 62 | Q5HLD8 | 230 | Y2049_STAEQ Uncharacterized oxidoreductase SE... | 255 | 0.000000002 | 60.1 | 24 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 63 | Q8CN40 | 230 | Y2036_STAES Uncharacterized oxidoreductase SE... | 255 | 0.000000002 | 60.1 | 24 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 64 | P23238 | 241 | PHBB_ZOORA Acetoacetyl-CoA reductase OS=Zoogl... | 250 | 0.000000002 | 60.1 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 65 | P37769 | 253 | KDUD_ECOLI 2-dehydro-3-deoxy-D-gluconate 5-de... | 254 | 0.000000002 | 60.1 | 26 | 43 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 66 | Q13268 | 258 | DHRS2_HUMAN Dehydrogenase/reductase SDR famil... | 233 | 0.000000002 | 60.1 | 28 | 44 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB. | 67 | P50205 | 241 | PHBB_RHIME Acetoacetyl-CoA reductase OS=melil... | 254 | 0.000000003 | 59.7 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018454; F:acetoacetyl-CoA reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:UniProtKB-KW. | 68 | Q49117 | 248 | Y182_METEA Uncharacterized oxidoreductase Mex... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 69 | P0A0I0 | 246 | FABG_STAAW 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 70 | Q6G9Y2 | 246 | FABG_STAAS 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 71 | Q6GHK4 | 246 | FABG_STAAR 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 72 | P99093 | 246 | FABG_STAAN 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 73 | P0A0H9 | 246 | FABG_STAAM 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 74 | Q5HGK2 | 246 | FABG_STAAC 3-oxoacyl-[acyl-carrier-protein] r... | 276 | 0.000000003 | 59.7 | 24 | 43 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 75 | P19337 | 249 | BAIA2_EUBSP Bile acid 7-dehydroxylase 2 OS=Eu... | 270 | 0.000000004 | 59.3 | 26 | 40 | | | | | | | | | | | GO:0033792; F:bile-acid 7alpha-dehydroxylase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 76 | Q4A054 | 234 | Y0419_STAS1 Uncharacterized oxidoreductase SS... | 226 | 0.000000004 | 59.3 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 77 | Q8CPI3 | 244 | FABG_STAES 3-oxoacyl-[acyl-carrier-protein] r... | 245 | 0.000000004 | 59.3 | 24 | 46 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 78 | Q5HPW0 | 244 | FABG_STAEQ 3-oxoacyl-[acyl-carrier-protein] r... | 245 | 0.000000004 | 59.3 | 24 | 46 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 79 | P07914 | 249 | BAIA1_EUBSP Bile acid 7-dehydroxylase 1/3 OS=... | 271 | 0.000000005 | 58.9 | 25 | 40 | | | | | | | | | | | GO:0033792; F:bile-acid 7alpha-dehydroxylase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 80 | P37694 | 287 | HETN_NOSS1 Ketoacyl reductase hetN OS=Nostoc ... | 260 | 0.000000006 | 59.3 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043158; P:heterocyst differentiation; IEA:UniProtKB-KW. | 81 | P55434 | 248 | Y4EK_RHISN Uncharacterized short-chain type d... | 233 | 0.000000008 | 58.5 | 25 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | O70503 | 312 | DHB12_MOUSE Estradiol 17-beta-dehydrogenase 1... | 229 | 0.000000008 | 58.9 | 24 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005518; F:collagen binding; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0001968; F:fibronectin binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030198; P:extracellular matrix organization; IDA:MGI.::GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:MGI.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 83 | Q5ZJG8 | 331 | HSDL1_CHICK Hydroxysteroid dehydrogenase-like... | 243 | 0.00000001 | 58.9 | 27 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 84 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 229 | 0.00000001 | 58.5 | 22 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 85 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 227 | 0.00000001 | 58.5 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 281 | 0.00000002 | 57.8 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 87 | Q99714 | 261 | HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase ty... | 243 | 0.00000002 | 57.4 | 25 | 41 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.::GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 88 | P45200 | 252 | Y1430_HAEIN Probable NADP-dependent dehydroge... | 234 | 0.00000002 | 57.4 | 28 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 89 | Q05528 | 253 | KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de... | 254 | 0.00000002 | 57.4 | 26 | 42 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 90 | Q83RE8 | 248 | YDFG_SHIFL NADP-dependent L-serine/L-allo-thr... | 265 | 0.00000002 | 57 | 23 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 91 | P57432 | 244 | FABG_BUCAI 3-oxoacyl-[acyl-carrier-protein] r... | 227 | 0.00000003 | 56.6 | 24 | 46 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] |