Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL048C
Length:
640
Number of sequences:
5887
Description:
YKL048C ELM1 SGDID:S000001531, Chr XI from 349136-347214, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
781Q5REX1    925   SIK2_PONAB Serine/threonine-protein kinase SI...3120.00000000009     68.9     22     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
782Q8SRK8    322   KAPC_ENCCU Probable cAMP-dependent protein ki...1730.00000000009     67     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.
783Q12469    655   SKM1_YEAST Serine/threonine-protein kinase SK...1300.00000000009     68.6     32     55GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000920; P:cytokinetic cell separation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.
784P24723    683   KPCL_HUMAN Protein kinase C eta type OS=Homo ...3300.00000000009     68.6     24     40GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
785Q61083    619   M3K2_MOUSE Mitogen-activated protein kinase k...3010.00000000009     68.6     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
786P13286    388   PHKG1_RAT Phosphorylase b kinase gamma cataly...1350.0000000001     67.8     31     51GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
787Q6PHZ2    499   KCC2D_MOUSE Calcium/calmodulin-dependent prot...2840.0000000001     68.2     26     42GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0030315; C:T-tubule; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0060048; P:cardiac muscle contraction; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
788Q13557    499   KCC2D_HUMAN Calcium/calmodulin-dependent prot...2840.0000000001     68.2     26     42GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
789Q8BYR2    1129   LATS1_MOUSE Serine/threonine-protein kinase L...1940.0000000001     68.9     30     45GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0000819; P:sister chromatid segregation; ISS:UniProtKB.
790Q8ICR0    509   CDPK2_PLAF7 Calcium-dependent protein kinase ...2790.0000000001     68.2     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum.
791O75011    652   NAK1_SCHPO Serine/threonine-protein kinase na...2320.0000000001     68.6     27     43GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.
792Q95266    499   KCC2D_PIG Calcium/calmodulin-dependent protei...2840.0000000001     68.2     26     42GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
793P27636    974   CDC15_YEAST Cell division control protein 15 ...2820.0000000001     68.6     26     42GO:0005935; C:cellular bud neck; TAS:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000910; P:cytokinesis; IMP:SGD.::GO:0007138; P:meiotic anaphase II; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.
794P12688    680   YPK1_YEAST Serine/threonine-protein kinase YP...3340.0000000001     68.6     27     42GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0061093; P:negative regulation of phospholipid translocation; IMP:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
795Q0VD22    486   STK33_BOVIN Serine/threonine-protein kinase 3...3280.0000000001     67.8     23     43GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
796B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...3230.0000000001     68.6     24     41GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
797Q8G6P9    690   PKNB_BIFLO Probable serine/threonine-protein ...2550.0000000001     68.2     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
798B4QK53    769   PLK4_DROSI Serine/threonine-protein kinase PL...3210.0000000001     68.6     24     40GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
799O95835    1130   LATS1_HUMAN Serine/threonine-protein kinase L...1950.0000000001     68.6     30     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051220; P:cytoplasmic sequestering of protein; IMP:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0035329; P:hippo signaling cascade; IDA:BHF-UCL.::GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0000819; P:sister chromatid segregation; IDA:UniProtKB.
800P40231    332   CSK2A_SCHPO Casein kinase II subunit alpha OS...1290.0000000001     67     30     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005956; C:protein kinase CK2 complex; TAS:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
801D2I3C6    784   DCLK2_AILME Serine/threonine-protein kinase D...2800.0000000001     68.2     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
802Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...3110.0000000001     68.6     21     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
803Q5UQ78    450   YR517_MIMIV Putative serine/threonine-protein...2180.0000000001     67.8     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
804Q3SYZ2    384   MAPK3_BOVIN MAP kinase-activated protein kina...1220.0000000001     67.4     36     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
805Q5R667    435   STK40_PONAB Serine/threonine-protein kinase 4...1710.0000000001     67.4     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
806Q38872    544   CDPK6_ARATH Calcium-dependent protein kinase ...2230.0000000001     67.8     27     42GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0010359; P:regulation of anion channel activity; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.
807Q39008    608   M3K1_ARATH Mitogen-activated protein kinase k...1370.0000000001     68.2     33     53GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0019900; F:kinase binding; IPI:TAIR.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IDA:TAIR.
808P10102    672   KPCA_RABIT Protein kinase C alpha type OS=Ory...1310.0000000001     68.2     33     53GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
809O14427    971   CLA4_CANAX Serine/threonine-protein kinase CL...1640.0000000001     68.2     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
810P34103    992   PK4_DICDI Protein kinase 4 OS=Dictyostelium d...2270.0000000001     68.2     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
811Q9VA38    1105   WARTS_DROME Serine/threonine-protein kinase W...1640.0000000001     68.6     29     43GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IGI:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; TAS:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.
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