rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
721 | P18334 | 360 | CSK2A_CAEEL Casein kinase II subunit alpha OS... | 134 | 0.00000000004 | 68.9 | 31 | 51 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 722 | Q9Y6E0 | 443 | STK24_HUMAN Serine/threonine-protein kinase 2... | 115 | 0.00000000004 | 69.3 | 42 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0048679; P:regulation of axon regeneration; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 723 | O43930 | 277 | PRKY_HUMAN Serine/threonine-protein kinase PR... | 126 | 0.00000000004 | 67.8 | 34 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | | 724 | Q61410 | 762 | KGP2_MOUSE cGMP-dependent protein kinase 2 OS... | 224 | 0.00000000004 | 69.7 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 725 | Q9R0G8 | 1455 | NRK_MOUSE Nik-related protein kinase OS=Mus m... | 275 | 0.00000000004 | 70.1 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007256; P:activation of JNKK activity; IDA:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007567; P:parturition; IMP:MGI.::GO:0060721; P:regulation of spongiotrophoblast cell proliferation; IMP:MGI. | 726 | O88445 | 282 | AURKC_MOUSE Aurora kinase C OS=Mus musculus (... | 329 | 0.00000000004 | 67.8 | 23 | 41 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 727 | Q0IHQ8 | 951 | STK10_XENTR Serine/threonine-protein kinase 1... | 273 | 0.00000000004 | 70.1 | 27 | 42 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 728 | O54863 | 358 | TSSK2_MOUSE Testis-specific serine/threonine-... | 323 | 0.00000000004 | 68.6 | 25 | 40 | GO:0001669; C:acrosomal vesicle; IDA:UniProtKB.::GO:0005814; C:centriole; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007286; P:spermatid development; IMP:UniProtKB. | 729 | Q99JT2 | 416 | MST4_MOUSE Serine/threonine-protein kinase MS... | 115 | 0.00000000004 | 68.9 | 41 | 54 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB. | 730 | O70126 | 345 | AURKB_MOUSE Aurora kinase B OS=Mus musculus (... | 320 | 0.00000000004 | 68.6 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 731 | Q1LUA6 | 3028 | TRIO_DANRE Triple functional domain protein O... | 287 | 0.00000000004 | 70.1 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 732 | P54735 | 505 | SPKD_SYNY3 Serine/threonine-protein kinase D ... | 118 | 0.00000000004 | 69.3 | 34 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 733 | Q9FKW4 | 523 | CDPKS_ARATH Calcium-dependent protein kinase ... | 319 | 0.00000000004 | 69.3 | 26 | 39 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 734 | P70268 | 946 | PKN1_MOUSE Serine/threonine-protein kinase N1... | 317 | 0.00000000004 | 69.7 | 25 | 41 | GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0017049; F:GTP-Rho binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 735 | Q7ZVS3 | 940 | PLK4_DANRE Serine/threonine-protein kinase PL... | 356 | 0.00000000005 | 69.7 | 24 | 44 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 736 | Q99KH8 | 431 | STK24_MOUSE Serine/threonine-protein kinase 2... | 115 | 0.00000000005 | 68.9 | 42 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 737 | Q5R4F3 | 898 | TAOK3_PONAB Serine/threonine-protein kinase T... | 175 | 0.00000000005 | 69.7 | 33 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB. | 738 | Q9UBS0 | 482 | KS6B2_HUMAN Ribosomal protein S6 kinase beta-... | 159 | 0.00000000005 | 68.9 | 31 | 48 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0006412; P:translation; TAS:ProtInc. | 739 | Q9DG02 | 475 | KCC2D_XENLA Calcium/calmodulin-dependent prot... | 284 | 0.00000000005 | 68.9 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 740 | O76484 | 353 | CSK2A_SPOFR Casein kinase II subunit alpha OS... | 134 | 0.00000000005 | 68.6 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 741 | P07934 | 388 | PHKG1_MOUSE Phosphorylase b kinase gamma cata... | 135 | 0.00000000005 | 68.6 | 31 | 52 | GO:0005964; C:phosphorylase kinase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:InterPro. | 742 | A7KAL2 | 960 | ATG1_PENCW Serine/threonine-protein kinase AT... | 222 | 0.00000000005 | 69.7 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 743 | Q16644 | 382 | MAPK3_HUMAN MAP kinase-activated protein kina... | 122 | 0.00000000005 | 68.6 | 37 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 744 | P00540 | 346 | MOS_HUMAN Proto-oncogene serine/threonine-pro... | 172 | 0.00000000005 | 68.2 | 33 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 745 | P49071 | 359 | MAPK2_DROME MAP kinase-activated protein kina... | 268 | 0.00000000005 | 68.6 | 26 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 746 | Q54VV7 | 1126 | Y0111_DICDI Probable serine/threonine-protein... | 279 | 0.00000000005 | 69.7 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 747 | Q9UTH3 | 775 | PPK6_SCHPO Serine/threonine-protein kinase pp... | 173 | 0.00000000005 | 69.3 | 32 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0045719; P:negative regulation of glycogen biosynthetic process; ISS:PomBase. | 748 | Q9XUJ7 | 722 | DKF1_CAEEL Serine/threonine-protein kinase dk... | 322 | 0.00000000005 | 69.3 | 27 | 41 | GO:0030424; C:axon; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase. | 749 | Q0KHT7 | 784 | Y2666_DROME Probable serine/threonine-protein... | 169 | 0.00000000005 | 69.3 | 31 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0002009; P:morphogenesis of an epithelium; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 750 | P38691 | 1029 | KSP1_YEAST Serine/threonine-protein kinase KS... | 226 | 0.00000000005 | 69.7 | 24 | 48 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0030447; P:filamentous growth; IMP:SGD.::GO:2000220; P:regulation of pseudohyphal growth; IMP:SGD. | 751 | Q16816 | 387 | PHKG1_HUMAN Phosphorylase b kinase gamma cata... | 120 | 0.00000000005 | 68.6 | 34 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005964; C:phosphorylase kinase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:Reactome.::GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; TAS:Reactome. |