Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YKL032C
Length:
597
Number of sequences:
5887
Description:
YKL032C IXR1 SGDID:S000001515, Chr XI from 381858-380065, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P30681    210   HMGB2_MOUSE High mobility group protein B2 OS...866.5     32.7     27     44GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0008301; F:DNA binding, bending; ISS:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:MGI.
GO:0006288; P:base-excision repair, DNA ligation; ISS:UniProtKB.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0043388; P:positive regulation of DNA binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0048545; P:response to steroid hormone stimulus; IMP:MGI.::GO:0007289; P:spermatid nucleus differentiation; IMP:MGI.
32Q28EW4    566   SOX13_XENTR Transcription factor Sox-13 OS=Xe...660.13     38.9     30     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33P35711    763   SOX5_HUMAN Transcription factor SOX-5 OS=Homo...660.87     36.2     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
34P35712    828   SOX6_HUMAN Transcription factor SOX-6 OS=Homo...672.2     35     31     51GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0007517; P:muscle organ development; NAS:UniProtKB.::GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
35Q91ZW1    244   TFAM_RAT Transcription factor A, mitochondria...620.15     38.1     32     53GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0070363; F:mitochondrial light strand promoter sense binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:RGD.
GO:0006264; P:mitochondrial DNA replication; TAS:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006391; P:transcription initiation from mitochondrial promoter; ISS:UniProtKB.
36P40645    827   SOX6_MOUSE Transcription factor SOX-6 OS=Mus ...672.5     35     31     51GO:0005667; C:transcription factor complex; IC:MGI.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0035051; P:cardiac cell differentiation; IDA:MGI.::GO:0051216; P:cartilage development; IGI:MGI.::GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0016458; P:gene silencing; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0042692; P:muscle cell differentiation; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021778; P:oligodendrocyte cell fate specification; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37P40647    757   SOX5_XENLA Transcription factor Sox-5 OS=Xeno...660.73     36.6     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38P35710    763   SOX5_MOUSE Transcription factor SOX-5 OS=Mus ...661     36.2     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0051216; P:cartilage development; IGI:MGI.::GO:0045165; P:cell fate commitment; IGI:MGI.::GO:0021953; P:central nervous system neuron differentiation; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0048709; P:oligodendrocyte differentiation; IMP:MGI.::GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060164; P:regulation of timing of neuron differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39Q5RCU4    787   SOX6_PONAB Transcription factor SOX-6 OS=Pong...673     34.7     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40P0C6E5    187   HMG3M_HUMAN Putative high mobility group prot...681     35     29     46GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
41B3DM43    753   SOX5_XENTR Transcription factor Sox-5 OS=Xeno...661.3     35.8     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42P26584    207   HMGB2_CHICK High mobility group protein B2 OS...1290.00005     48.1     28     43GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
GO:0006288; P:base-excision repair, DNA ligation; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
43B1H349    777   SOX6_XENTR Transcription factor Sox-6 OS=Xeno...849.8     33.1     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44P87057    108   NHP6_SCHPO Non-histone chromosomal protein 6 ...620.41     35     29     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; ISS:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; ISS:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; ISS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45Q69FB1    229   SRY_BUBBU Sex-determining region Y protein OS...650.24     37.4     34     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q62565    311   SRY_MUSSI Sex-determining region Y protein OS...494.4     33.5     33     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47Q9XS37    229   SRY_BOSMU Sex-determining region Y protein OS...512     34.3     35     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030238; P:male sex determination; IEA:InterPro.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q4PBZ9    99   NHP6_USTMA Non-histone chromosomal protein 6 ...520.019     38.9     35     62GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49P40630    243   TFAM_MOUSE Transcription factor A, mitochondr...630.037     40     33     54GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; TAS:MGI.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070363; F:mitochondrial light strand promoter sense binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:MGI.
GO:0033108; P:mitochondrial respiratory chain complex assembly; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006391; P:transcription initiation from mitochondrial promoter; ISS:UniProtKB.
50Q62563    355   SRY_MUSSP Sex-determining region Y protein OS...469.4     32.7     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51P47792    297   SX19A_DANRE Transcription factor Sox-19a OS=D...660.78     35.8     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52P40625    99   HMG_TETPY High mobility group protein OS=Tetr...600.0003     44.7     38     57GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
53Q05738    395   SRY_MOUSE Sex-determining region Y protein OS...520.0002     47.8     42     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0008584; P:male gonad development; IDA:MGI.::GO:0030238; P:male sex determination; IGI:MGI.::GO:0010629; P:negative regulation of gene expression; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54Q6EJB7    300   SOX3_DANRE Transcription factor Sox-3 OS=Dani...581.4     35     33     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0007417; P:central nervous system development; IMP:ZFIN.::GO:0030182; P:neuron differentiation; IMP:ZFIN.::GO:0043049; P:otic placode formation; IMP:ZFIN.::GO:0007422; P:peripheral nervous system development; IMP:ZFIN.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55P40622    114   HMG1A_CHITE Mobility group protein 1A OS=Chir...750.056     37.7     31     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
56B2RPK0    211   HGB1A_HUMAN Putative high mobility group prot...607.1     32.7     30     48GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
57P0CO24    116   NHP6_CRYNJ Non-histone chromosomal protein 6 ...550.31     35.4     31     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58P0CO25    116   NHP6_CRYNB Non-histone chromosomal protein 6 ...550.31     35.4     31     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59O49596    144   HMGB2_ARATH High mobility group B protein 2 O...730.006     41.2     34     52GO:0000785; C:chromatin; TAS:TAIR.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0003682; F:chromatin binding; TAS:TAIR.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0030527; F:structural constituent of chromatin; TAS:TAIR.
GO:0006333; P:chromatin assembly or disassembly; TAS:TAIR.
60Q90941    1633   PB1_CHICK Protein polybromo-1 OS=Gallus gallu...581.8     35.4     40     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61Q5FWM3    307   SOX3B_XENLA Transcription factor Sox-3-B OS=X...660.86     35.8     29     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0001704; P:formation of primary germ layer; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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